Click here to switch to the map view.

The map label for this gene is lcrH [H]

Identifier: 46447018

GI number: 46447018

Start: 1661342

End: 1661914

Strand: Direct

Name: lcrH [H]

Synonym: pc1384

Alternate gene names: 46447018

Gene position: 1661342-1661914 (Clockwise)

Preceding gene: 46447017

Following gene: 46447019

Centisome position: 68.81

GC content: 34.21

Gene sequence:

>573_bases
ATGAAAGGTTCTCGTGGAGTAAAAAGTCAGATGAAAAAAGACGCCTTAAATGCTTCGATGGTTGAAGATGAGAAGTTCAA
AAAATCTTATGGGGATATCATGGGACGTATGTTCAGTGAAGGAATGACACCCAAAGATGCCATGGGGGTAAACAGCAACA
TTTTAGAAAGTGTATATGCACAAGCTTACCGTCTATATAATACAGGAAAATATATTGAAGCCGTTCATTTGTTTCGTGTT
TTAATTATGATGAACTATGCAGAATCGAAGTATGTATTAGGACTAGCCGCTTGTTTTCATATGATGAAAGAATATAAAAA
TGCCATACAAACTTATACAATGTGTAGTGCGATCGATCCTAATACACCTATCCCCTATTATCACTCTTCTGATTGCTTTA
TTCAAATGAAAGACTATTTATCAGCGATGCTTTGTCTACAATTGGCTATTGATAAATCTCAAAATAAGCCCGAATTTGCA
AAAATTAAAGAACGTGCGATTTTAAGTTTAGAAAGTTTAAAACAACAAAATCTCCCATCACAACCCATAAAAATGGAAGA
AGACGAACTTTAA

Upstream 100 bases:

>100_bases
AACGCAAAATTCACTAGATTAATGATATGAAGCATTCTGAGTGTAAAAAAGAACTTTCTCATTAAATTAAAGACATAAGA
ATAAGAAATAGGAGGAGACC

Downstream 100 bases:

>100_bases
ATAAACTGCTTAAAACATTAGACAGATGAATTAAAGGTGAAATTTAAGTCATCACAATCATCATTAATTTATCTGGTTAG
ACAATCATAAATTTACTTAA

Product: putative low calcium response protein H

Products: NA

Alternate protein names: Salmonella invasin chaperone [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKGSRGVKSQMKKDALNASMVEDEKFKKSYGDIMGRMFSEGMTPKDAMGVNSNILESVYAQAYRLYNTGKYIEAVHLFRV
LIMMNYAESKYVLGLAACFHMMKEYKNAIQTYTMCSAIDPNTPIPYYHSSDCFIQMKDYLSAMLCLQLAIDKSQNKPEFA
KIKERAILSLESLKQQNLPSQPIKMEEDEL

Sequences:

>Translated_190_residues
MKGSRGVKSQMKKDALNASMVEDEKFKKSYGDIMGRMFSEGMTPKDAMGVNSNILESVYAQAYRLYNTGKYIEAVHLFRV
LIMMNYAESKYVLGLAACFHMMKEYKNAIQTYTMCSAIDPNTPIPYYHSSDCFIQMKDYLSAMLCLQLAIDKSQNKPEFA
KIKERAILSLESLKQQNLPSQPIKMEEDEL
>Mature_190_residues
MKGSRGVKSQMKKDALNASMVEDEKFKKSYGDIMGRMFSEGMTPKDAMGVNSNILESVYAQAYRLYNTGKYIEAVHLFRV
LIMMNYAESKYVLGLAACFHMMKEYKNAIQTYTMCSAIDPNTPIPYYHSSDCFIQMKDYLSAMLCLQLAIDKSQNKPEFA
KIKERAILSLESLKQQNLPSQPIKMEEDEL

Specific function: Type III secretion-associated chaperone required for sipB and sipC stabilization. Prevents premature association of sipB with sipC, which may lead to their targeting for degradation. Along with invF, required for transcription activation of sigDE (sopB pi

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lcrH/sycD chaperone family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005415
- InterPro:   IPR016379
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 21726; Mature: 21726

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
7.9 %Met     (Translated Protein)
10.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
7.9 %Met     (Mature Protein)
10.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSRGVKSQMKKDALNASMVEDEKFKKSYGDIMGRMFSEGMTPKDAMGVNSNILESVYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHH
QAYRLYNTGKYIEAVHLFRVLIMMNYAESKYVLGLAACFHMMKEYKNAIQTYTMCSAIDP
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTPIPYYHSSDCFIQMKDYLSAMLCLQLAIDKSQNKPEFAKIKERAILSLESLKQQNLPS
CCCCCCEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
QPIKMEEDEL
CCCCCCCCCC
>Mature Secondary Structure
MKGSRGVKSQMKKDALNASMVEDEKFKKSYGDIMGRMFSEGMTPKDAMGVNSNILESVYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHH
QAYRLYNTGKYIEAVHLFRVLIMMNYAESKYVLGLAACFHMMKEYKNAIQTYTMCSAIDP
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTPIPYYHSSDCFIQMKDYLSAMLCLQLAIDKSQNKPEFAKIKERAILSLESLKQQNLPS
CCCCCCEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
QPIKMEEDEL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA