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The map label for this gene is nhaA2 [H]

Identifier: 46446969

GI number: 46446969

Start: 1592839

End: 1593366

Strand: Direct

Name: nhaA2 [H]

Synonym: pc1335

Alternate gene names: 46446969

Gene position: 1592839-1593366 (Clockwise)

Preceding gene: 46446968

Following gene: 46446970

Centisome position: 65.97

GC content: 34.85

Gene sequence:

>528_bases
TTGATGCCTCAATTATCTACACCCATTTCTGAAAAAGATCATATTTTAGGCAATCTAAATGCTCCTGTAGTCTTGGTAGA
ATATGGAGACTATCAGTGCAAAACATGCGCCTTAACTCATCCCATTGTCAAGCAACTCTTAAAAGAGATGCGCGGACAAT
TATGTTTTGCATTTCGTCATTTCCCACTTAAAAACTCTCATCCATTAGCATTTATTGCTTCTCAAGCTGCAGAAGCGGCA
GCATTACAAAATAAATTTTGGCAAATGCATGAATGTCTTTATCATCATCACCATGCTCTAAGTTTAGAAGCTTTTCCAAG
TTATGCCGAAGAAATTCAATTGAATATCAAATTGTTTAATGAAAACTTACAAAATCCTTCTCTCATTTCTTGTATTGAAG
AAAATTTTTGTAGCGGTTTAGATAGTGGTGTTAATGGAACACCCTGTTTTTTTATCAATAAAGAACGTTATGATGGGGAT
CGATCTTATGATACTTTATTGTCCGCTCTAAAAAATGCTGTCAGCTGA

Upstream 100 bases:

>100_bases
AAAGGAATTATTCTCTGAAGCGATGTTTCTCCGATCGATATTAAACCAGGAACTGAGGAAATCTTAAAATCTTAAAAAAA
TTGTCTATCAAAGGAGATCA

Downstream 100 bases:

>100_bases
TATAAATCGATGAGGATTTACTTTCAATTTTTAGAAAATCAACATGTGCCATTAATTTATGCTTGGTTTCAAACCCCGCA
TATTAAAAAATGGTACGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MMPQLSTPISEKDHILGNLNAPVVLVEYGDYQCKTCALTHPIVKQLLKEMRGQLCFAFRHFPLKNSHPLAFIASQAAEAA
ALQNKFWQMHECLYHHHHALSLEAFPSYAEEIQLNIKLFNENLQNPSLISCIEENFCSGLDSGVNGTPCFFINKERYDGD
RSYDTLLSALKNAVS

Sequences:

>Translated_175_residues
MMPQLSTPISEKDHILGNLNAPVVLVEYGDYQCKTCALTHPIVKQLLKEMRGQLCFAFRHFPLKNSHPLAFIASQAAEAA
ALQNKFWQMHECLYHHHHALSLEAFPSYAEEIQLNIKLFNENLQNPSLISCIEENFCSGLDSGVNGTPCFFINKERYDGD
RSYDTLLSALKNAVS
>Mature_175_residues
MMPQLSTPISEKDHILGNLNAPVVLVEYGDYQCKTCALTHPIVKQLLKEMRGQLCFAFRHFPLKNSHPLAFIASQAAEAA
ALQNKFWQMHECLYHHHHALSLEAFPSYAEEIQLNIKLFNENLQNPSLISCIEENFCSGLDSGVNGTPCFFINKERYDGD
RSYDTLLSALKNAVS

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 19757; Mature: 19757

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPQLSTPISEKDHILGNLNAPVVLVEYGDYQCKTCALTHPIVKQLLKEMRGQLCFAFRH
CCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC
FPLKNSHPLAFIASQAAEAAALQNKFWQMHECLYHHHHALSLEAFPSYAEEIQLNIKLFN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEC
ENLQNPSLISCIEENFCSGLDSGVNGTPCFFINKERYDGDRSYDTLLSALKNAVS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MMPQLSTPISEKDHILGNLNAPVVLVEYGDYQCKTCALTHPIVKQLLKEMRGQLCFAFRH
CCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC
FPLKNSHPLAFIASQAAEAAALQNKFWQMHECLYHHHHALSLEAFPSYAEEIQLNIKLFN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEC
ENLQNPSLISCIEENFCSGLDSGVNGTPCFFINKERYDGDRSYDTLLSALKNAVS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA