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The map label for this gene is lpxB [H]

Identifier: 46446945

GI number: 46446945

Start: 1567795

End: 1568478

Strand: Direct

Name: lpxB [H]

Synonym: pc1311

Alternate gene names: 46446945

Gene position: 1567795-1568478 (Clockwise)

Preceding gene: 46446944

Following gene: 161611305

Centisome position: 64.93

GC content: 36.7

Gene sequence:

>684_bases
GTGGAAGATTGGAGAACATTTTTATATCCTCTTGGGTTTTTATCTTCGATAGCTTTTGGAGCACGTTTTATTGTCCAATG
GCTCCAGAGTGAAAAGCAACATAGAAGTGTTGTGACGCCATTCTTTTGGTATTTATCTTTAACAGGAAATACTTTATTAG
CTATCCACAGTTTTATTCAAATTCAATACCACATTTGTCTCGTTCAAGTCTGTAATGGTGTGATTTCTTGGCGCAACCTC
AATTTAATGCACCCTTATCGTCGACAATTTACCTTTCAATCTGTTATAAAATATCTAGGAATTGCATTTGTTTTAACAAC
ACTCGCTTTTTTTGCTCAGGATTATTTTCTAACGCAAGATGGAAGCTGGTTTCGCGTTCCAAAAGCTCCCTGGCAATCTC
ATTCTCAAGTGGAGTATTCGTTGTGGTGGCATGGTTTGGGAACTATTTCTTATTTATTGTTTTCAAGTCGGTTTTGGGTT
CAATGGTGGCTAGCTGAAAAATCTCATTCTAGCGAACTTTCCACTTCTTTTTGGTGGCTAAGTTTGAGTGGAGCTATCCT
TTCTATTGTCTACTTTTCACATATTCAAGATAGCGTCAATTTAATTGGCCCTTTAATCGGAATGGTTCCTTATATTCGAA
ATTTAATGCTATTGAAAAACGCTAAAATAGCGGCTGCAAAATGA

Upstream 100 bases:

>100_bases
ATACTGTTTCTGATTTGTTAGCTGTCTGTTGGATGAGAAAAAGACACCTTCATTACCAAATTGAAGATGATTTCTCACCA
AAAAATTAAAAAGGGATTTT

Downstream 100 bases:

>100_bases
AAAATTGTTTTATTTTTGCCGGGGAAGCAAGCGGTGATTTGCATGGTAGTCGCTTGATGCGTGCCTTGAAAGAGCAATTC
GTTTTTTCCTCTTTAAATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MEDWRTFLYPLGFLSSIAFGARFIVQWLQSEKQHRSVVTPFFWYLSLTGNTLLAIHSFIQIQYHICLVQVCNGVISWRNL
NLMHPYRRQFTFQSVIKYLGIAFVLTTLAFFAQDYFLTQDGSWFRVPKAPWQSHSQVEYSLWWHGLGTISYLLFSSRFWV
QWWLAEKSHSSELSTSFWWLSLSGAILSIVYFSHIQDSVNLIGPLIGMVPYIRNLMLLKNAKIAAAK

Sequences:

>Translated_227_residues
MEDWRTFLYPLGFLSSIAFGARFIVQWLQSEKQHRSVVTPFFWYLSLTGNTLLAIHSFIQIQYHICLVQVCNGVISWRNL
NLMHPYRRQFTFQSVIKYLGIAFVLTTLAFFAQDYFLTQDGSWFRVPKAPWQSHSQVEYSLWWHGLGTISYLLFSSRFWV
QWWLAEKSHSSELSTSFWWLSLSGAILSIVYFSHIQDSVNLIGPLIGMVPYIRNLMLLKNAKIAAAK
>Mature_227_residues
MEDWRTFLYPLGFLSSIAFGARFIVQWLQSEKQHRSVVTPFFWYLSLTGNTLLAIHSFIQIQYHICLVQVCNGVISWRNL
NLMHPYRRQFTFQSVIKYLGIAFVLTTLAFFAQDYFLTQDGSWFRVPKAPWQSHSQVEYSLWWHGLGTISYLLFSSRFWV
QWWLAEKSHSSELSTSFWWLSLSGAILSIVYFSHIQDSVNLIGPLIGMVPYIRNLMLLKNAKIAAAK

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG3952

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lpxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835
- InterPro:   IPR011499
- ProDom:   PD339292 [H]

Pfam domain/function: PF07578 LAB_N; PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 26562; Mature: 26562

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDWRTFLYPLGFLSSIAFGARFIVQWLQSEKQHRSVVTPFFWYLSLTGNTLLAIHSFIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IQYHICLVQVCNGVISWRNLNLMHPYRRQFTFQSVIKYLGIAFVLTTLAFFAQDYFLTQD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GSWFRVPKAPWQSHSQVEYSLWWHGLGTISYLLFSSRFWVQWWLAEKSHSSELSTSFWWL
CCEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHH
SLSGAILSIVYFSHIQDSVNLIGPLIGMVPYIRNLMLLKNAKIAAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEDWRTFLYPLGFLSSIAFGARFIVQWLQSEKQHRSVVTPFFWYLSLTGNTLLAIHSFIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IQYHICLVQVCNGVISWRNLNLMHPYRRQFTFQSVIKYLGIAFVLTTLAFFAQDYFLTQD
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GSWFRVPKAPWQSHSQVEYSLWWHGLGTISYLLFSSRFWVQWWLAEKSHSSELSTSFWWL
CCEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHH
SLSGAILSIVYFSHIQDSVNLIGPLIGMVPYIRNLMLLKNAKIAAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]