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The map label for this gene is ybeX [C]

Identifier: 46446689

GI number: 46446689

Start: 1254970

End: 1256343

Strand: Direct

Name: ybeX [C]

Synonym: pc1055

Alternate gene names: 46446689

Gene position: 1254970-1256343 (Clockwise)

Preceding gene: 46446688

Following gene: 46446690

Centisome position: 51.98

GC content: 33.41

Gene sequence:

>1374_bases
TTGCCTCTCAATCTCACCCTTTTCTTACTTATTATATTAATCATCGGACTGTTTTGTCTTACAGCGATTAATACAGCTCT
TCGTAGACTCCATAAAAAGAACTCAAAAAAACAACTGAATTTAAGTGGTAAACTTTTCTTCTATCGACATTTTCACGCTA
TTTTCTTCCGTAATCAAGAAGCAGAAGAATTATTTTTTATAACCACCCTTGCGCAAAATATTTTGCGCTTTATTTACGTC
ATATTTTCATTAACAATTTTAATCCAATTAAATTTGATTTCTTGGTTAGTCAATCCTATAACACACAGCTCATCTTTGAT
CATTAACTGGCCTGCCGGCTTGTTGTGCTTAATAAGTTTATTTTTCCTTTTTTTTATTGTAGGAGACTATCTCGCACGTA
TTCTTGGTGGACGTTATCCTGAAATAGCTATTCAGGTCTGTGCTCTAGTGTCCTCTCTATTTATGACTCTTATTTTTCCA
CTAACTTTTTTGTTTTTGAAATTTTCTCAAGCATTTGCACGAACTATTTATTTTAATCCTTTATCTGAAACTGCTTCTAA
GGCCAAACAAGAAATTATAGAAATCATTGAAGAATCCAATTTTACAGCAAGCCTGGACCCCCATGACAAAAAATTAATTG
AAGGGGTCATGGATTTTAAAGATCGCATTGCTCGAGAAGTGATGGTTCCTCGCGTGGATATTTTTAGCTTAGCCCACGAC
ACAACAATAGAACAGGCCGCAGTTCTAATATATAATGAAGGCTATAGCCGCATACCAGTTTTTAAACATACTCTTGATAA
CATCATCGGTGTCCTAATGTACAAAGATGTTTTAGCTAAGTATATGGAATTTTCTCGCACGCAAGATACTAAAATCTTAC
AAGCACCTATTTCAGGTTTAGTTAAAAATGTTTTATATACGCCTGAAACAAAGAAAATTTCCCATCTTTTACAAGAATTT
CGCAAAAAACAAGTTCACCTTGCAATCATTGTTGATGAATATGGAGGGACAGAAGGAATTGTCACTATTGAGGATATTTT
AGAAGAAATTGTTGGAGATATCGCTGATGAATATGATGAAAGTGAAGAATCTCTTTTTGTTGCTTTACCTGAAGGAGGAT
GGTTAATTGATGCCAGAATGACTATTTTTGATATCGAAGAGCAATTTGATATTGAAATTGCTCAAGATGGCGACTACGAT
ACAATTGGAGGATATATTTTTCATGAAACAGGAAATATTCCTTCTAAAGGATTTGTTTTAACAAAACCAAATTTCGAATT
AAAAGTAATTCGCTCAAATGATAGGCGTGTAGAAAAACTTAAAATCAGATCAATTCGATTAGATTCGGAAGAAAAGGATG
AATTTTCATCATAG

Upstream 100 bases:

>100_bases
AATCTACTGTATCTCATTCTTTTACATAAATGAACTTTTAAAAAACTTTTAGATTTTTATTAAACTTTATAACAAGGTTC
CTTTTAACAGGAGAATCGAT

Downstream 100 bases:

>100_bases
CTATTGGTTTTCCCTCTTCCAAAATAAAATTTTTTTGCTTAGCAAAATCTCAAAAAGTTCAGATTAATCCCTTTAGGTTT
AAACTAGATTTGGAAATCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MPLNLTLFLLIILIIGLFCLTAINTALRRLHKKNSKKQLNLSGKLFFYRHFHAIFFRNQEAEELFFITTLAQNILRFIYV
IFSLTILIQLNLISWLVNPITHSSSLIINWPAGLLCLISLFFLFFIVGDYLARILGGRYPEIAIQVCALVSSLFMTLIFP
LTFLFLKFSQAFARTIYFNPLSETASKAKQEIIEIIEESNFTASLDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHD
TTIEQAAVLIYNEGYSRIPVFKHTLDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEF
RKKQVHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFDIEEQFDIEIAQDGDYD
TIGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIRSIRLDSEEKDEFSS

Sequences:

>Translated_457_residues
MPLNLTLFLLIILIIGLFCLTAINTALRRLHKKNSKKQLNLSGKLFFYRHFHAIFFRNQEAEELFFITTLAQNILRFIYV
IFSLTILIQLNLISWLVNPITHSSSLIINWPAGLLCLISLFFLFFIVGDYLARILGGRYPEIAIQVCALVSSLFMTLIFP
LTFLFLKFSQAFARTIYFNPLSETASKAKQEIIEIIEESNFTASLDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHD
TTIEQAAVLIYNEGYSRIPVFKHTLDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEF
RKKQVHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFDIEEQFDIEIAQDGDYD
TIGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIRSIRLDSEEKDEFSS
>Mature_456_residues
PLNLTLFLLIILIIGLFCLTAINTALRRLHKKNSKKQLNLSGKLFFYRHFHAIFFRNQEAEELFFITTLAQNILRFIYVI
FSLTILIQLNLISWLVNPITHSSSLIINWPAGLLCLISLFFLFFIVGDYLARILGGRYPEIAIQVCALVSSLFMTLIFPL
TFLFLKFSQAFARTIYFNPLSETASKAKQEIIEIIEESNFTASLDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHDT
TIEQAAVLIYNEGYSRIPVFKHTLDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEFR
KKQVHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFDIEEQFDIEIAQDGDYDT
IGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIRSIRLDSEEKDEFSS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=352, Percent_Identity=28.9772727272727, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI94681046, Length=262, Percent_Identity=26.3358778625954, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI40068053, Length=263, Percent_Identity=23.574144486692, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40068055, Length=263, Percent_Identity=23.574144486692, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=257, Percent_Identity=33.4630350194552, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI145693175, Length=400, Percent_Identity=22, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790664, Length=333, Percent_Identity=24.9249249249249, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082033, Length=247, Percent_Identity=25.1012145748988, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788119, Length=235, Percent_Identity=25.531914893617, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324512, Length=154, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 52451; Mature: 52320

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNLTLFLLIILIIGLFCLTAINTALRRLHKKNSKKQLNLSGKLFFYRHFHAIFFRNQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEHHHHHHHHHCCCCC
AEELFFITTLAQNILRFIYVIFSLTILIQLNLISWLVNPITHSSSLIINWPAGLLCLISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
FFLFFIVGDYLARILGGRYPEIAIQVCALVSSLFMTLIFPLTFLFLKFSQAFARTIYFNP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSETASKAKQEIIEIIEESNFTASLDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHD
HHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
TTIEQAAVLIYNEGYSRIPVFKHTLDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGL
CCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VKNVLYTPETKKISHLLQEFRKKQVHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDE
HHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCC
SEESLFVALPEGGWLIDARMTIFDIEEQFDIEIAQDGDYDTIGGYIFHETGNIPSKGFVL
CCCCEEEEECCCCEEEECCEEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEE
TKPNFELKVIRSNDRRVEKLKIRSIRLDSEEKDEFSS
ECCCCEEEEEECCCCHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure 
PLNLTLFLLIILIIGLFCLTAINTALRRLHKKNSKKQLNLSGKLFFYRHFHAIFFRNQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEHHHHHHHHHCCCCC
AEELFFITTLAQNILRFIYVIFSLTILIQLNLISWLVNPITHSSSLIINWPAGLLCLISL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
FFLFFIVGDYLARILGGRYPEIAIQVCALVSSLFMTLIFPLTFLFLKFSQAFARTIYFNP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSETASKAKQEIIEIIEESNFTASLDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHD
HHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
TTIEQAAVLIYNEGYSRIPVFKHTLDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGL
CCHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VKNVLYTPETKKISHLLQEFRKKQVHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDE
HHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCC
SEESLFVALPEGGWLIDARMTIFDIEEQFDIEIAQDGDYDTIGGYIFHETGNIPSKGFVL
CCCCEEEEECCCCEEEECCEEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEE
TKPNFELKVIRSNDRRVEKLKIRSIRLDSEEKDEFSS
ECCCCEEEEEECCCCHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]