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The map label for this gene is potC [H]

Identifier: 46446507

GI number: 46446507

Start: 1055627

End: 1056394

Strand: Direct

Name: potC [H]

Synonym: pc0873

Alternate gene names: 46446507

Gene position: 1055627-1056394 (Clockwise)

Preceding gene: 46446506

Following gene: 46446508

Centisome position: 43.72

GC content: 33.72

Gene sequence:

>768_bases
ATGAAAAAAAGTCCATTAAGTTTTTGGATCACAGTTTTTGTTCTCATTTTTTTATACGTTCCCATTCTCGTCTTAATCAT
TAATTCTTTTAATGATTCACGATTTGGTGGACAATGGGTTGGTTTTACTTATAAATGGTATGATCGGCTTTGGAATGAGC
ATAAAATGTGGTATGCTTTGCGTAATTCTTTAATCGTAGGTGTGTCTGCGACAATTGTGTCGACTTTTTTAGGAACGTGT
GCAGCTTTTGCTTTACACCTTTATAAATCCAAATTACAAAATTTTCATTACGGACTCATTTATACCCCGCTACTTATTCC
TGATATTCTAACAGGAATTAGTCTTCTTCTATTTTTTGTCACTGTAAATGTAAAATTGGGCCTTTTTACGGTCTTTATTG
CACACACCACATTTTGCATGAGTTATGTTACAATGGTTATGCTTTCAAAACTGCAGAATTTTGATTTTACTTTGATAGAA
GCCGCACAAGATTTAGGAGCAAATACCTGGACCTTAATCAAAAAGATTTTACTTCCTTTATTAGCACCAGGATTAATGAC
TGGAGCTCTTTTAGCTTTTATTCTTTCTATTGACGATTTTGTCATTACTTTTTTTGTTGCGGGGCAAGGGGTTTTGACGT
TGCCTGTTTATGTTTACAATATGATTAAGTTTGGATCGACACCTATAGTGAATGCGCTTTCTGTTCTGATTTTGGGCGTG
ACATTTGTATTTATATTTTTTACACAACGTTTATCTAAAGAGGATTGA

Upstream 100 bases:

>100_bases
TTTCTGCTCTTTTGTCTTTAGTTATCTTTTTACCACTTTTAGCCTATGTTTTTATTTCTACTCGGCAAAAAAAAATTGAA
GTAGAAGTGAGGAACAGAGA

Downstream 100 bases:

>100_bases
GCATGAAAAAATACTTTCTCTTATTACTTTCCCTGTTCGCTAGCCTTAGTATTTTTACGGCATGCCAAAATACGCTTGTT
CCAGAGCTGCACATCATGAT

Product: spermidine/putrescine ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKKSPLSFWITVFVLIFLYVPILVLIINSFNDSRFGGQWVGFTYKWYDRLWNEHKMWYALRNSLIVGVSATIVSTFLGTC
AAFALHLYKSKLQNFHYGLIYTPLLIPDILTGISLLLFFVTVNVKLGLFTVFIAHTTFCMSYVTMVMLSKLQNFDFTLIE
AAQDLGANTWTLIKKILLPLLAPGLMTGALLAFILSIDDFVITFFVAGQGVLTLPVYVYNMIKFGSTPIVNALSVLILGV
TFVFIFFTQRLSKED

Sequences:

>Translated_255_residues
MKKSPLSFWITVFVLIFLYVPILVLIINSFNDSRFGGQWVGFTYKWYDRLWNEHKMWYALRNSLIVGVSATIVSTFLGTC
AAFALHLYKSKLQNFHYGLIYTPLLIPDILTGISLLLFFVTVNVKLGLFTVFIAHTTFCMSYVTMVMLSKLQNFDFTLIE
AAQDLGANTWTLIKKILLPLLAPGLMTGALLAFILSIDDFVITFFVAGQGVLTLPVYVYNMIKFGSTPIVNALSVLILGV
TFVFIFFTQRLSKED
>Mature_255_residues
MKKSPLSFWITVFVLIFLYVPILVLIINSFNDSRFGGQWVGFTYKWYDRLWNEHKMWYALRNSLIVGVSATIVSTFLGTC
AAFALHLYKSKLQNFHYGLIYTPLLIPDILTGISLLLFFVTVNVKLGLFTVFIAHTTFCMSYVTMVMLSKLQNFDFTLIE
AAQDLGANTWTLIKKILLPLLAPGLMTGALLAFILSIDDFVITFFVAGQGVLTLPVYVYNMIKFGSTPIVNALSVLILGV
TFVFIFFTQRLSKED

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=229, Percent_Identity=37.9912663755458, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1787081, Length=263, Percent_Identity=38.0228136882129, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787714, Length=243, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28854; Mature: 28854

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]