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The map label for this gene is glpG [H]

Identifier: 46446094

GI number: 46446094

Start: 589035

End: 590210

Strand: Reverse

Name: glpG [H]

Synonym: pc0460

Alternate gene names: 46446094

Gene position: 590210-589035 (Counterclockwise)

Preceding gene: 46446095

Following gene: 46446093

Centisome position: 24.44

GC content: 35.12

Gene sequence:

>1176_bases
ATGCGTATAATCGGCATCTTAGAAGATGAAAAAAAAGGACTAACTTTCTCATCTTTTCTTCATCAAAAAGAAATAGCACA
TCAACTAGAAATGGAACCTAATTATGATTGGGGTAGTGCAGATTACGGCTCGAGTCAATGTAAGATATGGATTCATGACG
AAGATCAAGTAGAGCAAGCCATTCAGTGGTTGACTCATTTCAAAGAAAACCCCTCCGACCCTATTTTTCATTTTGTTCAG
CCTATCTCATCTTCTTCATTCTCCCCATCTCCAATATCTAATCCAGAAATTGAACCATCTTCAACACGAAAAACACATGG
CTGGGAAACAGCAACAATGGGATGGATAACCCGTAGCTTTCTCATTCTTTGTTCAATTCTTTTTGCTACTACTCAATTGA
TTAAACCCTCTGTTCCTATTCCAGCCAATACATCAGTTGTAAGTTTAGTTTCTTCTCCTATTGATCAAACCCTTCTTTAC
GACTATCCTCTCTTTTATGAACTCATTAATCGTTTTATTGATATGTATGGTTATGAAGGATTAAAAGACCCCACAAATTT
AACTTTGGAAGCACAAATTTTACTTCAAAAAATTCATCATACTCCCTTTTGGAAAGGTTTTTACGAAGAAATATTTGTAA
AAAATAGAGTTGAAAACGCATTAAAAGGGGATTTAGCTCCCCCCTTGTTCGAAAAGATTCGTGAAGGTCAAATTTGGCGC
CTTTTTTCACCTGCTTTACTTCACGGAGATATTTTTCATTTATTTTTCAATATGCTTTGGTTAATGGTCCTTGGAAAACA
ACTTGAACTGCGATTAAAAGCTTCACGGTATTTGTTATTCATTTTAATCACGGGAATTTTTTCAAATACATCCCAATATT
TGATGAGTGGCTCAAATTTTGTGGGTTTTTCAGGAATTCTATGTGCCATGTTAACATTTATCTGGATCAGACAGAATCAA
ACTCCTTGGGAAGGGTATCAATTAGATCGCTTATCTTTTTCTTTTATGATGTTCTTCATTATAGGAATGGCCCTTTTACA
ATTAGTTTCTTTGTTTTTAGAAAAATTCTTTCAAATTGAAATCGCTCCTCATATTGCTAATACAGCCCATCTCAGTGGGG
CTTTAATCGGCATCATTTTGGGACGATTGGATTTTTTCAGTTGGAGCCATTCTTAA

Upstream 100 bases:

>100_bases
AACTGTTTGTCAAAATGGAGGAAAAATTCATATTGTTCCCCTCATGCCAGGCCTATCTACTTCTTCTATTATAAAAAAAA
TTCAGGGGCTAATTTGAATC

Downstream 100 bases:

>100_bases
TATGTCTGTAAGAGATCTAACCATTCTTGGTTGCTCAAGTCAGCAACCTACACGCTTTCGTAATCATGGAGCCTATTTAT
TAAGATGGAATGGGGAGGGG

Product: putative glpG protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRIIGILEDEKKGLTFSSFLHQKEIAHQLEMEPNYDWGSADYGSSQCKIWIHDEDQVEQAIQWLTHFKENPSDPIFHFVQ
PISSSSFSPSPISNPEIEPSSTRKTHGWETATMGWITRSFLILCSILFATTQLIKPSVPIPANTSVVSLVSSPIDQTLLY
DYPLFYELINRFIDMYGYEGLKDPTNLTLEAQILLQKIHHTPFWKGFYEEIFVKNRVENALKGDLAPPLFEKIREGQIWR
LFSPALLHGDIFHLFFNMLWLMVLGKQLELRLKASRYLLFILITGIFSNTSQYLMSGSNFVGFSGILCAMLTFIWIRQNQ
TPWEGYQLDRLSFSFMMFFIIGMALLQLVSLFLEKFFQIEIAPHIANTAHLSGALIGIILGRLDFFSWSHS

Sequences:

>Translated_391_residues
MRIIGILEDEKKGLTFSSFLHQKEIAHQLEMEPNYDWGSADYGSSQCKIWIHDEDQVEQAIQWLTHFKENPSDPIFHFVQ
PISSSSFSPSPISNPEIEPSSTRKTHGWETATMGWITRSFLILCSILFATTQLIKPSVPIPANTSVVSLVSSPIDQTLLY
DYPLFYELINRFIDMYGYEGLKDPTNLTLEAQILLQKIHHTPFWKGFYEEIFVKNRVENALKGDLAPPLFEKIREGQIWR
LFSPALLHGDIFHLFFNMLWLMVLGKQLELRLKASRYLLFILITGIFSNTSQYLMSGSNFVGFSGILCAMLTFIWIRQNQ
TPWEGYQLDRLSFSFMMFFIIGMALLQLVSLFLEKFFQIEIAPHIANTAHLSGALIGIILGRLDFFSWSHS
>Mature_391_residues
MRIIGILEDEKKGLTFSSFLHQKEIAHQLEMEPNYDWGSADYGSSQCKIWIHDEDQVEQAIQWLTHFKENPSDPIFHFVQ
PISSSSFSPSPISNPEIEPSSTRKTHGWETATMGWITRSFLILCSILFATTQLIKPSVPIPANTSVVSLVSSPIDQTLLY
DYPLFYELINRFIDMYGYEGLKDPTNLTLEAQILLQKIHHTPFWKGFYEEIFVKNRVENALKGDLAPPLFEKIREGQIWR
LFSPALLHGDIFHLFFNMLWLMVLGKQLELRLKASRYLLFILITGIFSNTSQYLMSGSNFVGFSGILCAMLTFIWIRQNQ
TPWEGYQLDRLSFSFMMFFIIGMALLQLVSLFLEKFFQIEIAPHIANTAHLSGALIGIILGRLDFFSWSHS

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=160, Percent_Identity=30.625, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 45041; Mature: 45041

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGILEDEKKGLTFSSFLHQKEIAHQLEMEPNYDWGSADYGSSQCKIWIHDEDQVEQA
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
IQWLTHFKENPSDPIFHFVQPISSSSFSPSPISNPEIEPSSTRKTHGWETATMGWITRSF
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LILCSILFATTQLIKPSVPIPANTSVVSLVSSPIDQTLLYDYPLFYELINRFIDMYGYEG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCC
LKDPTNLTLEAQILLQKIHHTPFWKGFYEEIFVKNRVENALKGDLAPPLFEKIREGQIWR
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEE
LFSPALLHGDIFHLFFNMLWLMVLGKQLELRLKASRYLLFILITGIFSNTSQYLMSGSNF
ECCHHHHHHHHHHHHHHHHHHHHHCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
VGFSGILCAMLTFIWIRQNQTPWEGYQLDRLSFSFMMFFIIGMALLQLVSLFLEKFFQIE
CCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IAPHIANTAHLSGALIGIILGRLDFFSWSHS
ECCHHCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIIGILEDEKKGLTFSSFLHQKEIAHQLEMEPNYDWGSADYGSSQCKIWIHDEDQVEQA
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
IQWLTHFKENPSDPIFHFVQPISSSSFSPSPISNPEIEPSSTRKTHGWETATMGWITRSF
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LILCSILFATTQLIKPSVPIPANTSVVSLVSSPIDQTLLYDYPLFYELINRFIDMYGYEG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCC
LKDPTNLTLEAQILLQKIHHTPFWKGFYEEIFVKNRVENALKGDLAPPLFEKIREGQIWR
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEE
LFSPALLHGDIFHLFFNMLWLMVLGKQLELRLKASRYLLFILITGIFSNTSQYLMSGSNF
ECCHHHHHHHHHHHHHHHHHHHHHCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
VGFSGILCAMLTFIWIRQNQTPWEGYQLDRLSFSFMMFFIIGMALLQLVSLFLEKFFQIE
CCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IAPHIANTAHLSGALIGIILGRLDFFSWSHS
ECCHHCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA