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The map label for this gene is elaC

Identifier: 46446093

GI number: 46446093

Start: 588113

End: 589033

Strand: Reverse

Name: elaC

Synonym: pc0459

Alternate gene names: 46446093

Gene position: 589033-588113 (Counterclockwise)

Preceding gene: 46446094

Following gene: 46446092

Centisome position: 24.4

GC content: 36.7

Gene sequence:

>921_bases
ATGTCTGTAAGAGATCTAACCATTCTTGGTTGCTCAAGTCAGCAACCTACACGCTTTCGTAATCATGGAGCCTATTTATT
AAGATGGAATGGGGAGGGGTTTTTATTCGACCCTGGCGAAGGAACTCAGCGACAGTTTATCTTTGCTAATATTGCTCCTA
GTGTTATCAATCGAATTTTCATTTCTCACTTTCATGGAGACCATTGTTTAGGATTAGGGTCCATTTTAATGCGTCTCAAT
TTAGACAAAGTGCGCCATCCGATTCATTGTTATTACCCTGCAAGCGGCAAAAAATACTTTGATCGTTTGCGCTATGGAAC
AATTTATCATGAAATGATTCATGTGGTAGAGCACCCAGTTTCTAAAGCAGGTTTAGTCGAAGATGATGGAAGATTCAAAA
TTGAAGCGGCTTTTTTACAACACGGTATAGAAAATATCGGTTGGCGTATTACAGAAGCAGATACGAGAAAATTCGATAAT
CAAAAACTTATTGATCGGGGCATCAGAGGCTCTTTAGTCAAGGAATTGCAAGAAAAAGGACAATTAAACTTAGATGGGCA
AACCATTTATTTAGATGATGTTAGCTGGATTAGAAAAGGAGATCAATTTTCTGTAGTGATAGATACACTTCCTTGCCAAA
ATGCTATTGACATCGCTCGTAATGCAACTTTACTTTTATGCGAAAGTACTTATTTAGAAGAACACAAAGAATTGGCCCGG
TTGCATAGCCATTTAACAGCAAAGCAAGCAGCTTTGATTGCAAAAGAAGCCAATGCCAAGCAGTTAATTTTAACTCATTT
TTCTGCTCGCTATCAAAATTTAAAATTATTTGAACAAGAAGCTCGAACTATTTTTGCTAATACTTTTGTGGCAAACGATT
TGATCACATTTCCTTTTACGAAAGTTAATTTGAAATCGTAA

Upstream 100 bases:

>100_bases
GAAATCGCTCCTCATATTGCTAATACAGCCCATCTCAGTGGGGCTTTAATCGGCATCATTTTGGGACGATTGGATTTTTT
CAGTTGGAGCCATTCTTAAT

Downstream 100 bases:

>100_bases
TAAAATTTTATAGTCTTATATGAGCAAGGTAAATTCATGTATATTGCGGCTTGTTATCAATTTCTTGAACATTTAAAAGT
TGTTAAAAATGCTTCTGAGC

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSVRDLTILGCSSQQPTRFRNHGAYLLRWNGEGFLFDPGEGTQRQFIFANIAPSVINRIFISHFHGDHCLGLGSILMRLN
LDKVRHPIHCYYPASGKKYFDRLRYGTIYHEMIHVVEHPVSKAGLVEDDGRFKIEAAFLQHGIENIGWRITEADTRKFDN
QKLIDRGIRGSLVKELQEKGQLNLDGQTIYLDDVSWIRKGDQFSVVIDTLPCQNAIDIARNATLLLCESTYLEEHKELAR
LHSHLTAKQAALIAKEANAKQLILTHFSARYQNLKLFEQEARTIFANTFVANDLITFPFTKVNLKS

Sequences:

>Translated_306_residues
MSVRDLTILGCSSQQPTRFRNHGAYLLRWNGEGFLFDPGEGTQRQFIFANIAPSVINRIFISHFHGDHCLGLGSILMRLN
LDKVRHPIHCYYPASGKKYFDRLRYGTIYHEMIHVVEHPVSKAGLVEDDGRFKIEAAFLQHGIENIGWRITEADTRKFDN
QKLIDRGIRGSLVKELQEKGQLNLDGQTIYLDDVSWIRKGDQFSVVIDTLPCQNAIDIARNATLLLCESTYLEEHKELAR
LHSHLTAKQAALIAKEANAKQLILTHFSARYQNLKLFEQEARTIFANTFVANDLITFPFTKVNLKS
>Mature_305_residues
SVRDLTILGCSSQQPTRFRNHGAYLLRWNGEGFLFDPGEGTQRQFIFANIAPSVINRIFISHFHGDHCLGLGSILMRLNL
DKVRHPIHCYYPASGKKYFDRLRYGTIYHEMIHVVEHPVSKAGLVEDDGRFKIEAAFLQHGIENIGWRITEADTRKFDNQ
KLIDRGIRGSLVKELQEKGQLNLDGQTIYLDDVSWIRKGDQFSVVIDTLPCQNAIDIARNATLLLCESTYLEEHKELARL
HSHLTAKQAALIAKEANAKQLILTHFSARYQNLKLFEQEARTIFANTFVANDLITFPFTKVNLKS

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family

Homologues:

Organism=Homo sapiens, GI8922122, Length=327, Percent_Identity=29.6636085626911, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI87082078, Length=305, Percent_Identity=33.7704918032787, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNZ_PARUW (Q6ME16)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007458.1
- ProteinModelPortal:   Q6ME16
- SMR:   Q6ME16
- STRING:   Q6ME16
- GeneID:   2781179
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0459
- NMPDR:   fig|264201.1.peg.459
- eggNOG:   COG1234
- HOGENOM:   HBG648406
- OMA:   HSTSTMA
- PhylomeDB:   Q6ME16
- ProtClustDB:   PRK00055
- BioCyc:   CPRO264201:PC0459-MONOMER
- HAMAP:   MF_01818
- InterPro:   IPR001279
- InterPro:   IPR013471
- TIGRFAMs:   TIGR02651

Pfam domain/function: PF00753 Lactamase_B

EC number: =3.1.26.11

Molecular weight: Translated: 34983; Mature: 34851

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRDLTILGCSSQQPTRFRNHGAYLLRWNGEGFLFDPGEGTQRQFIFANIAPSVINRIF
CCCCEEEEEECCCCCCCHHHCCCEEEEEECCCEEEECCCCCCCEEEEEECCCHHHHHHHH
ISHFHGDHCLGLGSILMRLNLDKVRHPIHCYYPASGKKYFDRLRYGTIYHEMIHVVEHPV
HHHCCCCHHHHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
SKAGLVEDDGRFKIEAAFLQHGIENIGWRITEADTRKFDNQKLIDRGIRGSLVKELQEKG
HHCCCEECCCCEEEEHHHHHCCHHHHCEEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHCC
QLNLDGQTIYLDDVSWIRKGDQFSVVIDTLPCQNAIDIARNATLLLCESTYLEEHKELAR
CEECCCCEEEECCHHHHHCCCCEEEEEECCCCCCHHHHHCCCEEEEEEHHHHHHHHHHHH
LHSHLTAKQAALIAKEANAKQLILTHFSARYQNLKLFEQEARTIFANTFVANDLITFPFT
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEE
KVNLKS
EEEECC
>Mature Secondary Structure 
SVRDLTILGCSSQQPTRFRNHGAYLLRWNGEGFLFDPGEGTQRQFIFANIAPSVINRIF
CCCEEEEEECCCCCCCHHHCCCEEEEEECCCEEEECCCCCCCEEEEEECCCHHHHHHHH
ISHFHGDHCLGLGSILMRLNLDKVRHPIHCYYPASGKKYFDRLRYGTIYHEMIHVVEHPV
HHHCCCCHHHHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
SKAGLVEDDGRFKIEAAFLQHGIENIGWRITEADTRKFDNQKLIDRGIRGSLVKELQEKG
HHCCCEECCCCEEEEHHHHHCCHHHHCEEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHCC
QLNLDGQTIYLDDVSWIRKGDQFSVVIDTLPCQNAIDIARNATLLLCESTYLEEHKELAR
CEECCCCEEEECCHHHHHCCCCEEEEEECCCCCCHHHHHCCCEEEEEEHHHHHHHHHHHH
LHSHLTAKQAALIAKEANAKQLILTHFSARYQNLKLFEQEARTIFANTFVANDLITFPFT
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEE
KVNLKS
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA