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The map label for this gene is rfaE [H]

Identifier: 46446095

GI number: 46446095

Start: 590214

End: 590726

Strand: Reverse

Name: rfaE [H]

Synonym: pc0461

Alternate gene names: 46446095

Gene position: 590726-590214 (Counterclockwise)

Preceding gene: 46446096

Following gene: 46446094

Centisome position: 24.47

GC content: 36.65

Gene sequence:

>513_bases
ATGAGCAAAACAATTGAGCTAGTTCCGTGGTCAATTGCCTATAAACAAAAAGTCATTGTTCCTGAGGAATTGAATCAGAA
AATTACCTCGCTTCGTTCAAATGAGGCAGTAATTGTCACATTGAACGGCTCTTTCGATCTCCTACATGCGGGACATTTGC
AAATTATTTATGAAGCATCTCAATTAGGTGATGTATTAATTGTCGCACTAAATAGTGATGAATCCATTAAGCGCTATAAA
AACCCAAATCGCCCTTTGATTTCTTTAGAGTATCGACTCCAAATGATGGCTGCATTAGAGTTTGTAAATTTCGTGACTTG
GTTTGAAGAAATGGATCCTTGCCACCTACTTTCTAAAATTAAACCTAATATCCATGTCAACGGTTCTGAATATGGCCATC
AATGTATCGAAGCTGAAACTGTTTGTCAAAATGGAGGAAAAATTCATATTGTTCCCCTCATGCCAGGCCTATCTACTTCT
TCTATTATAAAAAAAATTCAGGGGCTAATTTGA

Upstream 100 bases:

>100_bases
AAGGAATTACCGTGCATTTTGTTGACCATTATGATCAAGTCTTTAAAATTTCTTTTCCTAATAAACACCAAATGAAGCTT
TGTTAAGTGAAGGGTAAGTG

Downstream 100 bases:

>100_bases
ATCATGCGTATAATCGGCATCTTAGAAGATGAAAAAAAAGGACTAACTTTCTCATCTTTTCTTCATCAAAAAGAAATAGC
ACATCAACTAGAAATGGAAC

Product: ADP-heptose synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSKTIELVPWSIAYKQKVIVPEELNQKITSLRSNEAVIVTLNGSFDLLHAGHLQIIYEASQLGDVLIVALNSDESIKRYK
NPNRPLISLEYRLQMMAALEFVNFVTWFEEMDPCHLLSKIKPNIHVNGSEYGHQCIEAETVCQNGGKIHIVPLMPGLSTS
SIIKKIQGLI

Sequences:

>Translated_170_residues
MSKTIELVPWSIAYKQKVIVPEELNQKITSLRSNEAVIVTLNGSFDLLHAGHLQIIYEASQLGDVLIVALNSDESIKRYK
NPNRPLISLEYRLQMMAALEFVNFVTWFEEMDPCHLLSKIKPNIHVNGSEYGHQCIEAETVCQNGGKIHIVPLMPGLSTS
SIIKKIQGLI
>Mature_169_residues
SKTIELVPWSIAYKQKVIVPEELNQKITSLRSNEAVIVTLNGSFDLLHAGHLQIIYEASQLGDVLIVALNSDESIKRYKN
PNRPLISLEYRLQMMAALEFVNFVTWFEEMDPCHLLSKIKPNIHVNGSEYGHQCIEAETVCQNGGKIHIVPLMPGLSTSS
IIKKIQGLI

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=151, Percent_Identity=42.3841059602649, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 19098; Mature: 18966

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTIELVPWSIAYKQKVIVPEELNQKITSLRSNEAVIVTLNGSFDLLHAGHLQIIYEAS
CCCEEEEEEEEEECCEEEECHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEECC
QLGDVLIVALNSDESIKRYKNPNRPLISLEYRLQMMAALEFVNFVTWFEEMDPCHLLSKI
CCCCEEEEEECCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
KPNIHVNGSEYGHQCIEAETVCQNGGKIHIVPLMPGLSTSSIIKKIQGLI
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SKTIELVPWSIAYKQKVIVPEELNQKITSLRSNEAVIVTLNGSFDLLHAGHLQIIYEAS
CCEEEEEEEEEECCEEEECHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEECC
QLGDVLIVALNSDESIKRYKNPNRPLISLEYRLQMMAALEFVNFVTWFEEMDPCHLLSKI
CCCCEEEEEECCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
KPNIHVNGSEYGHQCIEAETVCQNGGKIHIVPLMPGLSTSSIIKKIQGLI
CCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA