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The map label for this gene is xerC [H]

Identifier: 46446092

GI number: 46446092

Start: 587087

End: 588076

Strand: Reverse

Name: xerC [H]

Synonym: pc0458

Alternate gene names: 46446092

Gene position: 588076-587087 (Counterclockwise)

Preceding gene: 46446093

Following gene: 46446091

Centisome position: 24.36

GC content: 34.95

Gene sequence:

>990_bases
ATGTATATTGCGGCTTGTTATCAATTTCTTGAACATTTAAAAGTTGTTAAAAATGCTTCTGAGCATACAATTCGAAATTA
TGCGATTGATCTAAATTTGTTCAAAAATTATCAGGAAAAGCAAATATTTGCTGAAAGTAAATTAGAACATATTAGCCCTA
AAATTTGTGCTCGCGAAAGTTATCAACAACGTCAATCTTGTCATGATGGTATTTTAAAATTGGAAGACATCGATCGTAAA
ACTATTCGAGGGTTTTTAGCATGGCTAAGTGCCAATCAACAAAATAAAAGAACGATTGCAAGACGTCTTTCTTCTTTAAG
AAGTTTTTTTAGATATCTTCAAACGCAAAATTTGATTCAAATAAATCCTACAGAAGAATTAGAAAGCCCCAAGCTGAATA
AAAAACTCCCTGTTTCCTTGAGTTATGAACAAGTCAGTCTGTTATTCGAACAACCAGACACTACATCCTATCTAGGATTT
CGTGACCGAACAATCATGGAACTTTTTTATAGTTCAGGTCTGCGAGTGAGCGAACTTGTTTCCTTAGATCGGCAAGATTT
TGATTATTCTAATTTGACTATTAAGCTTAAAGGAAAAGGAAAAAAACAACGCCTTATTCCTATCACTAAAAATGCTGCAA
AATGGATCCAGTCTTATCTATTACACATAGAGCGTTATCAAAATTTAGAGACTCACTCAGCTGAATCTGATTCAAATGCA
ATTTTTTTAAATAAATGGGGTACCCGTTTGACCACCCGATCCGTCGATCGAAAGTTTGACTTGTATCTGACGAAAAGTGG
GTTGGCTGGTAAAGTCACTCCTCACACAATCCGTCATACAATTGCTACACATTGGCTTGAAAATGGAATGGATCTCAAAA
CGATTCAATTACTTCTAGGACACCGTTCATTATCAACTACCACTATCTATACTCAGGTTTCAACAAAACTCAAACAGAAA
GTTTATGCCGATGCTCACCCTAGAGCTTAA

Upstream 100 bases:

>100_bases
TAATACTTTTGTGGCAAACGATTTGATCACATTTCCTTTTACGAAAGTTAATTTGAAATCGTAATAAAATTTTATAGTCT
TATATGAGCAAGGTAAATTC

Downstream 100 bases:

>100_bases
ATTCCCAATTGTTTGTCAGAAATTCTACATTTTTTACCAAAGAATTTTCTATTAGTTCATCAAATTTTTTTTATTTAAAT
TATTTTCAATTTTAATTAAT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MYIAACYQFLEHLKVVKNASEHTIRNYAIDLNLFKNYQEKQIFAESKLEHISPKICARESYQQRQSCHDGILKLEDIDRK
TIRGFLAWLSANQQNKRTIARRLSSLRSFFRYLQTQNLIQINPTEELESPKLNKKLPVSLSYEQVSLLFEQPDTTSYLGF
RDRTIMELFYSSGLRVSELVSLDRQDFDYSNLTIKLKGKGKKQRLIPITKNAAKWIQSYLLHIERYQNLETHSAESDSNA
IFLNKWGTRLTTRSVDRKFDLYLTKSGLAGKVTPHTIRHTIATHWLENGMDLKTIQLLLGHRSLSTTTIYTQVSTKLKQK
VYADAHPRA

Sequences:

>Translated_329_residues
MYIAACYQFLEHLKVVKNASEHTIRNYAIDLNLFKNYQEKQIFAESKLEHISPKICARESYQQRQSCHDGILKLEDIDRK
TIRGFLAWLSANQQNKRTIARRLSSLRSFFRYLQTQNLIQINPTEELESPKLNKKLPVSLSYEQVSLLFEQPDTTSYLGF
RDRTIMELFYSSGLRVSELVSLDRQDFDYSNLTIKLKGKGKKQRLIPITKNAAKWIQSYLLHIERYQNLETHSAESDSNA
IFLNKWGTRLTTRSVDRKFDLYLTKSGLAGKVTPHTIRHTIATHWLENGMDLKTIQLLLGHRSLSTTTIYTQVSTKLKQK
VYADAHPRA
>Mature_329_residues
MYIAACYQFLEHLKVVKNASEHTIRNYAIDLNLFKNYQEKQIFAESKLEHISPKICARESYQQRQSCHDGILKLEDIDRK
TIRGFLAWLSANQQNKRTIARRLSSLRSFFRYLQTQNLIQINPTEELESPKLNKKLPVSLSYEQVSLLFEQPDTTSYLGF
RDRTIMELFYSSGLRVSELVSLDRQDFDYSNLTIKLKGKGKKQRLIPITKNAAKWIQSYLLHIERYQNLETHSAESDSNA
IFLNKWGTRLTTRSVDRKFDLYLTKSGLAGKVTPHTIRHTIATHWLENGMDLKTIQLLLGHRSLSTTTIYTQVSTKLKQK
VYADAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=264, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789261, Length=328, Percent_Identity=31.4024390243902, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38291; Mature: 38291

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIAACYQFLEHLKVVKNASEHTIRNYAIDLNLFKNYQEKQIFAESKLEHISPKICARES
CHHHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHHCHHHHHHHHHHHHHHCCHHHHHHHH
YQQRQSCHDGILKLEDIDRKTIRGFLAWLSANQQNKRTIARRLSSLRSFFRYLQTQNLIQ
HHHHHHHHHCCEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
INPTEELESPKLNKKLPVSLSYEQVSLLFEQPDTTSYLGFRDRTIMELFYSSGLRVSELV
ECCHHHHCCCCCCCCCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
SLDRQDFDYSNLTIKLKGKGKKQRLIPITKNAAKWIQSYLLHIERYQNLETHSAESDSNA
HCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IFLNKWGTRLTTRSVDRKFDLYLTKSGLAGKVTPHTIRHTIATHWLENGMDLKTIQLLLG
EEEECCCCEEEHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
HRSLSTTTIYTQVSTKLKQKVYADAHPRA
CCCCCCEEEHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYIAACYQFLEHLKVVKNASEHTIRNYAIDLNLFKNYQEKQIFAESKLEHISPKICARES
CHHHHHHHHHHHHHHHHCCHHHHHHHHEEEHHHHHCHHHHHHHHHHHHHHCCHHHHHHHH
YQQRQSCHDGILKLEDIDRKTIRGFLAWLSANQQNKRTIARRLSSLRSFFRYLQTQNLIQ
HHHHHHHHHCCEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
INPTEELESPKLNKKLPVSLSYEQVSLLFEQPDTTSYLGFRDRTIMELFYSSGLRVSELV
ECCHHHHCCCCCCCCCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
SLDRQDFDYSNLTIKLKGKGKKQRLIPITKNAAKWIQSYLLHIERYQNLETHSAESDSNA
HCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IFLNKWGTRLTTRSVDRKFDLYLTKSGLAGKVTPHTIRHTIATHWLENGMDLKTIQLLLG
EEEECCCCEEEHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
HRSLSTTTIYTQVSTKLKQKVYADAHPRA
CCCCCCEEEHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA