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The map label for this gene is sohB [H]

Identifier: 46445858

GI number: 46445858

Start: 318295

End: 319332

Strand: Reverse

Name: sohB [H]

Synonym: pc0224

Alternate gene names: 46445858

Gene position: 319332-318295 (Counterclockwise)

Preceding gene: 46445861

Following gene: 46445857

Centisome position: 13.23

GC content: 37.48

Gene sequence:

>1038_bases
ATGCGCGACTCTATTTTTTACTCTGCTCTTAAAGCACTATTCGTCGCTTTTTGCGCTATTATTGGGATTTGTTTGGGCTT
TTTGGCTATAGGAATACTGATAGGATTGTCTGGAACCTCAAAAGATAGCCAAATTAGCTTTGTGAATACAGAAGAAATTT
TACCTAATGCTAAAGGTAAACGAGAAGTTGTGGCAAGTGATGCACCCGTCATTTTACAATTGAACATTGATGGAATCATT
GGAACAGAAAATTTAAATACACAGACGATAAGACAGCAGCTAATCGAGTCTCGGGAAGGAGCTTATAAAAATAATCGCGT
CAAAGCCCTTCTTCTTTATATTAATACGCCCGGTGGAACTGTTGCTGATGCAGATGGAATTTTCCAACTGCTCGCTGATT
ACAAAAAAAAATATCAAGTCCCTGTTTATGCTTACATCGATGGTTTATGTGCTTCAGGAGGTATGTATATTGCTCTTGCA
GCCGACAAAATTTACGCTAGTGACATTAGTTTGATTGGAAGTGTGGGCGTTATTGCCCCTACATTTATGAATGTCACAAA
ATTATTGGACAAATTGGGAGTTGAAACACTTACCATTTCAGCGGGTAAAGATAAAGACGCGATGAATCCACTTCGCCCTT
GGAAACCAGGGGAAGAAGACAACTATAGACAAATTATTGATTATTACTATACTCATTTTGTTGATCTTGTCTCTTCTCAT
CGCCCTGCTCTTTCTAAAGAAAAACTCGTAAAAGATTATGGAGCTCATGTTTTTCCTGCTCCAAATGCTGTAGAAAAAGG
GTATATTGATGTAAGCGGAGCTACAATCAGTGAAACCCTCAAAGAACTATTAATGACAATTGGTATTGATAATGACCATT
ATCAAGTGATTAGACTTGAAAACAAAGGATGGTGGAAAGGATTGTTTTCTTCTCAGTCCTCTTTGCTGAATGGGACAATT
AAACATGAAGCTTCTGTATCTCCTGTCATCAACCTTTTGTTGCAAAATCAATACCTTTACCTTTATTATCCCCAATAA

Upstream 100 bases:

>100_bases
AAACAGGTAATTGTTTATAACAATATTTTTTTATTTCACTCATCAACTAACAAGTAAGACAAATTATTTTATCACGTACT
TGTAAAAAGGTTTGGTATTT

Downstream 100 bases:

>100_bases
ATTTAAGGCACTAATGATTTATCATGGATAAACTCTATATTCTAGATGCCTCTGGCTACATTTATCGTTCTTATTTCGCG
ATTCGACAAATGACCAATGC

Product: putative proteinase IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRDSIFYSALKALFVAFCAIIGICLGFLAIGILIGLSGTSKDSQISFVNTEEILPNAKGKREVVASDAPVILQLNIDGII
GTENLNTQTIRQQLIESREGAYKNNRVKALLLYINTPGGTVADADGIFQLLADYKKKYQVPVYAYIDGLCASGGMYIALA
ADKIYASDISLIGSVGVIAPTFMNVTKLLDKLGVETLTISAGKDKDAMNPLRPWKPGEEDNYRQIIDYYYTHFVDLVSSH
RPALSKEKLVKDYGAHVFPAPNAVEKGYIDVSGATISETLKELLMTIGIDNDHYQVIRLENKGWWKGLFSSQSSLLNGTI
KHEASVSPVINLLLQNQYLYLYYPQ

Sequences:

>Translated_345_residues
MRDSIFYSALKALFVAFCAIIGICLGFLAIGILIGLSGTSKDSQISFVNTEEILPNAKGKREVVASDAPVILQLNIDGII
GTENLNTQTIRQQLIESREGAYKNNRVKALLLYINTPGGTVADADGIFQLLADYKKKYQVPVYAYIDGLCASGGMYIALA
ADKIYASDISLIGSVGVIAPTFMNVTKLLDKLGVETLTISAGKDKDAMNPLRPWKPGEEDNYRQIIDYYYTHFVDLVSSH
RPALSKEKLVKDYGAHVFPAPNAVEKGYIDVSGATISETLKELLMTIGIDNDHYQVIRLENKGWWKGLFSSQSSLLNGTI
KHEASVSPVINLLLQNQYLYLYYPQ
>Mature_345_residues
MRDSIFYSALKALFVAFCAIIGICLGFLAIGILIGLSGTSKDSQISFVNTEEILPNAKGKREVVASDAPVILQLNIDGII
GTENLNTQTIRQQLIESREGAYKNNRVKALLLYINTPGGTVADADGIFQLLADYKKKYQVPVYAYIDGLCASGGMYIALA
ADKIYASDISLIGSVGVIAPTFMNVTKLLDKLGVETLTISAGKDKDAMNPLRPWKPGEEDNYRQIIDYYYTHFVDLVSSH
RPALSKEKLVKDYGAHVFPAPNAVEKGYIDVSGATISETLKELLMTIGIDNDHYQVIRLENKGWWKGLFSSQSSLLNGTI
KHEASVSPVINLLLQNQYLYLYYPQ

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=212, Percent_Identity=26.8867924528302, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788064, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 37990; Mature: 37990

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSIFYSALKALFVAFCAIIGICLGFLAIGILIGLSGTSKDSQISFVNTEEILPNAKGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCCCC
REVVASDAPVILQLNIDGIIGTENLNTQTIRQQLIESREGAYKNNRVKALLLYINTPGGT
CEEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCC
VADADGIFQLLADYKKKYQVPVYAYIDGLCASGGMYIALAADKIYASDISLIGSVGVIAP
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
TFMNVTKLLDKLGVETLTISAGKDKDAMNPLRPWKPGEEDNYRQIIDYYYTHFVDLVSSH
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
RPALSKEKLVKDYGAHVFPAPNAVEKGYIDVSGATISETLKELLMTIGIDNDHYQVIRLE
CCCCCHHHHHHHHCCEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEC
NKGWWKGLFSSQSSLLNGTIKHEASVSPVINLLLQNQYLYLYYPQ
CCCHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRDSIFYSALKALFVAFCAIIGICLGFLAIGILIGLSGTSKDSQISFVNTEEILPNAKGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCCCC
REVVASDAPVILQLNIDGIIGTENLNTQTIRQQLIESREGAYKNNRVKALLLYINTPGGT
CEEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCC
VADADGIFQLLADYKKKYQVPVYAYIDGLCASGGMYIALAADKIYASDISLIGSVGVIAP
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
TFMNVTKLLDKLGVETLTISAGKDKDAMNPLRPWKPGEEDNYRQIIDYYYTHFVDLVSSH
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
RPALSKEKLVKDYGAHVFPAPNAVEKGYIDVSGATISETLKELLMTIGIDNDHYQVIRLE
CCCCCHHHHHHHHCCEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEC
NKGWWKGLFSSQSSLLNGTIKHEASVSPVINLLLQNQYLYLYYPQ
CCCHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]