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The map label for this gene is coaE

Identifier: 46445856

GI number: 46445856

Start: 314991

End: 315602

Strand: Reverse

Name: coaE

Synonym: pc0222

Alternate gene names: 46445856

Gene position: 315602-314991 (Counterclockwise)

Preceding gene: 46445857

Following gene: 46445855

Centisome position: 13.07

GC content: 34.97

Gene sequence:

>612_bases
ATGTTAAAATTAAGAAAAGTAGCCATAACAGGCGGTCTTTCATGTGGTAAATCTTCAGTTTGCCGTATCTTAAAAGAACT
TGGGGCTTACGCTGTAAGCGCTGACGAAATTGTCCATCACTTATTGTCATCCGATGTAAACGTTAGCCAAAAGGTTGTTG
ATTTATTAGGAAAATCTATTCTAAAAAACAATCAAATCCATCGTTCTTTATTAGCAGAGCGAGTTTTTCAAAATTATCGA
CTTTTAACCGGTTTAGAAAAAATTCTGCATCCGGCTGTGTATGGCGAAATAGAACAACAATATCAAAAACAACAGGATAG
CAAAAATCAGTTTCCTTTCTTCATTGCGGAAGTTCCCCTCTTATATGAAAGTGACGGTGCAAAATTTTTTGACACTATTA
TTTCGGTTGTTGCTGATCCAGAAATCAGCCTTCAGAGATTCAAAACACATACTCATAAGAGTGAAAAAGAGTTTCAAAGC
AGAATGGCAAGGCAGATATCGCCATTAGAAAAAGCTATTCGAGCCGACTATGTCGTCTTAAATAATGGAACTTTATCAGA
ACTTCAACAATCCCTGAGAGAATTATACCAAGAATTAAAAATATATATTTAA

Upstream 100 bases:

>100_bases
TAGAATCCATTTCTCATTTAGTTAAGAATACCATGGAAAATATTATAAATCTAAAGGTACCGTTGATTGTTAATATCCAT
ATTGGCAAAAATTGGAAAGA

Downstream 100 bases:

>100_bases
CTATTAACCATTTACATTGGAGTCTTATTTTTAATGGACCCAGAGAACAAAGAGAACACTTCAGTTGATACCTCGTTGAC
ATGTGAGGACAATTCAGTTG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLKLRKVAITGGLSCGKSSVCRILKELGAYAVSADEIVHHLLSSDVNVSQKVVDLLGKSILKNNQIHRSLLAERVFQNYR
LLTGLEKILHPAVYGEIEQQYQKQQDSKNQFPFFIAEVPLLYESDGAKFFDTIISVVADPEISLQRFKTHTHKSEKEFQS
RMARQISPLEKAIRADYVVLNNGTLSELQQSLRELYQELKIYI

Sequences:

>Translated_203_residues
MLKLRKVAITGGLSCGKSSVCRILKELGAYAVSADEIVHHLLSSDVNVSQKVVDLLGKSILKNNQIHRSLLAERVFQNYR
LLTGLEKILHPAVYGEIEQQYQKQQDSKNQFPFFIAEVPLLYESDGAKFFDTIISVVADPEISLQRFKTHTHKSEKEFQS
RMARQISPLEKAIRADYVVLNNGTLSELQQSLRELYQELKIYI
>Mature_203_residues
MLKLRKVAITGGLSCGKSSVCRILKELGAYAVSADEIVHHLLSSDVNVSQKVVDLLGKSILKNNQIHRSLLAERVFQNYR
LLTGLEKILHPAVYGEIEQQYQKQQDSKNQFPFFIAEVPLLYESDGAKFFDTIISVVADPEISLQRFKTHTHKSEKEFQS
RMARQISPLEKAIRADYVVLNNGTLSELQQSLRELYQELKIYI

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786292, Length=191, Percent_Identity=26.7015706806283, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=26.0204081632653, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=204, Percent_Identity=28.4313725490196, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644728, Length=196, Percent_Identity=25.5102040816327, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_PARUW (Q6MEQ3)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007221.1
- ProteinModelPortal:   Q6MEQ3
- SMR:   Q6MEQ3
- STRING:   Q6MEQ3
- GeneID:   2780268
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0222
- NMPDR:   fig|264201.1.peg.222
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   RIIEEQY
- PhylomeDB:   Q6MEQ3
- ProtClustDB:   PRK00081
- BioCyc:   CPRO264201:PC0222-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 23136; Mature: 23136

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLRKVAITGGLSCGKSSVCRILKELGAYAVSADEIVHHLLSSDVNVSQKVVDLLGKSI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKNNQIHRSLLAERVFQNYRLLTGLEKILHPAVYGEIEQQYQKQQDSKNQFPFFIAEVPL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCC
LYESDGAKFFDTIISVVADPEISLQRFKTHTHKSEKEFQSRMARQISPLEKAIRADYVVL
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEE
NNGTLSELQQSLRELYQELKIYI
CCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKLRKVAITGGLSCGKSSVCRILKELGAYAVSADEIVHHLLSSDVNVSQKVVDLLGKSI
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKNNQIHRSLLAERVFQNYRLLTGLEKILHPAVYGEIEQQYQKQQDSKNQFPFFIAEVPL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCC
LYESDGAKFFDTIISVVADPEISLQRFKTHTHKSEKEFQSRMARQISPLEKAIRADYVVL
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEE
NNGTLSELQQSLRELYQELKIYI
CCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA