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The map label for this gene is yggV [C]

Identifier: 46445719

GI number: 46445719

Start: 144259

End: 144858

Strand: Reverse

Name: yggV [C]

Synonym: pc0085

Alternate gene names: 46445719

Gene position: 144858-144259 (Counterclockwise)

Preceding gene: 46445720

Following gene: 46445718

Centisome position: 6.0

GC content: 35.83

Gene sequence:

>600_bases
ATGGAAATTCTTCTGGCAACTACTAATTTGCATAAAATTCGTGAATTTAAAGAAATGTGCAAAGCTTTTGCTCATCTAGA
AATTTTATCTCTTCATCAATTTCCAGCTTACATGTGTCCAGAAGAAGTGGGAACTAATTTTAAAGAAAACGCTATTTCTA
AAGCGGAACATGCAGCTAAACACCTCAATAGATGGGTTCTTGCTGATGATTCTGGTTTAGTTGTTCCCCGGTTAAGCGGA
AAACCAGGTATTTATTCTCGTCGGTTTGCTGGATTAGAGGCAACTGATGAAGAAAATCGTAAAAAACTTCTTTTAGAAAT
GAGACAACTAATAAATAAAGAAGATCGTACAGCTTATTATGAATGTTGTTTAGCGCTGTCTTCTCCAACTGGTTTACAAA
AGTGCGTTCAGGGAATTTGTGAAGGGTTTATTCTCAATGAAGCTAGAGGACGGAATGGATTTGGATATGACTCGTTATTT
GTAAAAAACGATTACGAAAAATCTTTTGCCGAGATCGACGAAGCCGTTAAAAACCGTATTTCTCATAGAAGAAAAGCTTT
TGAACGACTCTCTGCATTTTTAGAAAATCTTCGGGATTAA

Upstream 100 bases:

>100_bases
TTTGGTATTAATTCTAATGCATGTTATAACTGCAGTATAAACCCAAATTTAGGTCATAACGCCAAACCCTGCTCTTCCTA
ACCTTAAAAAATTGGTTCCT

Downstream 100 bases:

>100_bases
ATAAATGCATTATTATATTGATGGATACAATTTCCTTTTTAGATTAGTTCATGCTTATGAGAATTTGCAAAGTTCTCGAG
AGCAATTTATTTTAGATTTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MEILLATTNLHKIREFKEMCKAFAHLEILSLHQFPAYMCPEEVGTNFKENAISKAEHAAKHLNRWVLADDSGLVVPRLSG
KPGIYSRRFAGLEATDEENRKKLLLEMRQLINKEDRTAYYECCLALSSPTGLQKCVQGICEGFILNEARGRNGFGYDSLF
VKNDYEKSFAEIDEAVKNRISHRRKAFERLSAFLENLRD

Sequences:

>Translated_199_residues
MEILLATTNLHKIREFKEMCKAFAHLEILSLHQFPAYMCPEEVGTNFKENAISKAEHAAKHLNRWVLADDSGLVVPRLSG
KPGIYSRRFAGLEATDEENRKKLLLEMRQLINKEDRTAYYECCLALSSPTGLQKCVQGICEGFILNEARGRNGFGYDSLF
VKNDYEKSFAEIDEAVKNRISHRRKAFERLSAFLENLRD
>Mature_199_residues
MEILLATTNLHKIREFKEMCKAFAHLEILSLHQFPAYMCPEEVGTNFKENAISKAEHAAKHLNRWVLADDSGLVVPRLSG
KPGIYSRRFAGLEATDEENRKKLLLEMRQLINKEDRTAYYECCLALSSPTGLQKCVQGICEGFILNEARGRNGFGYDSLF
VKNDYEKSFAEIDEAVKNRISHRRKAFERLSAFLENLRD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI31657144, Length=151, Percent_Identity=33.112582781457, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789324, Length=199, Percent_Identity=39.1959798994975, Blast_Score=120, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17556833, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920712, Length=155, Percent_Identity=32.9032258064516, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_PARUW (Q6MF40)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007084.1
- ProteinModelPortal:   Q6MF40
- SMR:   Q6MF40
- STRING:   Q6MF40
- GeneID:   2780888
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0085
- NMPDR:   fig|264201.1.peg.85
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   Q6MF40
- ProtClustDB:   PRK00120
- BioCyc:   CPRO264201:PC0085-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22819; Mature: 22819

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILLATTNLHKIREFKEMCKAFAHLEILSLHQFPAYMCPEEVGTNFKENAISKAEHAAK
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHCCCHHHHHHHHHHHHHH
HLNRWVLADDSGLVVPRLSGKPGIYSRRFAGLEATDEENRKKLLLEMRQLINKEDRTAYY
HHHHEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
ECCLALSSPTGLQKCVQGICEGFILNEARGRNGFGYDSLFVKNDYEKSFAEIDEAVKNRI
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
SHRRKAFERLSAFLENLRD
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEILLATTNLHKIREFKEMCKAFAHLEILSLHQFPAYMCPEEVGTNFKENAISKAEHAAK
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHCCCHHHHHHHHHHHHHH
HLNRWVLADDSGLVVPRLSGKPGIYSRRFAGLEATDEENRKKLLLEMRQLINKEDRTAYY
HHHHEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
ECCLALSSPTGLQKCVQGICEGFILNEARGRNGFGYDSLFVKNDYEKSFAEIDEAVKNRI
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
SHRRKAFERLSAFLENLRD
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA