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The map label for this gene is prmA [H]

Identifier: 46445661

GI number: 46445661

Start: 42300

End: 43094

Strand: Direct

Name: prmA [H]

Synonym: pc0027

Alternate gene names: 46445661

Gene position: 42300-43094 (Clockwise)

Preceding gene: 46445657

Following gene: 46445662

Centisome position: 1.75

GC content: 37.48

Gene sequence:

>795_bases
ATGAAGGAGCTTTACAAAATTACCTTGAAGAATGATCTAACATTGGAACAAGCCTGGGAAATTTTGGAAGAAAATGCTTT
CGAATTAGCCTATGGGGAAGAAGAAGAGAGTAGGGGAATTCTTTATCTTTATTTAAACTCTGTGAATGAGGTTTCCGCTT
ATTTTTGGATTAAAGAAATTGAAAAGGTACAATTACCTAAAATTGATTGGGAATCACAATGGGCTTTGTATGGTTTAGAT
TTTAAAAATGGGTCGGTCCACCTTTCTTTTGACAAATTTGGAAGGAAAGCTGAGCCCATTTTACTCAAACCTGGCCCGGG
TTTTGGAGATTTATCTCATCCAACGACTTTACTTGTTTTAGAACTGATGAGTCAATATTTAACAACACAAAGTGTCATCG
ATATTGGAAGTGGAAGTGGTGTTTTGACTTTAGCTGCCCTTGCTCTAGGTGCTTCGTTTGCATATGGAGTGGACATCGAT
CCAGCAGCCATTGGACACGCTCAAGAAAATGCTAAGTTTAATCAAATGGAATCTCAATGTATTTTTATGCTACCAGAAGA
ATTTCAATTTCATTCTATTACAGTTCCTTTGATTGTGATGAATATGATTTTTTCTGAACAAAAAATTGCCTGGAATGCCC
TTTCCTCTTTGCATCGCTTACCGGGTTTACGTCTAATTTCCGGAATACGTCAAGAGGAGCGAGACGTCTACTTTGAGCAA
ACAAAAAACTGGGGGTGGAGATTAAAGGAAGAAAAAGAAAAAGAGGGATGGCTAGGCTTTGTTTTTGAGTGTTAA

Upstream 100 bases:

>100_bases
TTCAAGAAAAATATTAAAGAATTCATTTTCTCTCTATAATCATTACTTTGCTAAAAATTTTGCTAAGCATGAAAAATGAA
TAAATAAAAAGAGAATCGGA

Downstream 100 bases:

>100_bases
ATTAAAGAAGTGGTAAACTTCGATTTTAATTTAAGGCATTTTAAAAGATTTTTAAGTTCTTTTTGCTGTTTATCCTGAAA
TAGCACTTTCTTTGTGGAAA

Product: putative ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKELYKITLKNDLTLEQAWEILEENAFELAYGEEEESRGILYLYLNSVNEVSAYFWIKEIEKVQLPKIDWESQWALYGLD
FKNGSVHLSFDKFGRKAEPILLKPGPGFGDLSHPTTLLVLELMSQYLTTQSVIDIGSGSGVLTLAALALGASFAYGVDID
PAAIGHAQENAKFNQMESQCIFMLPEEFQFHSITVPLIVMNMIFSEQKIAWNALSSLHRLPGLRLISGIRQEERDVYFEQ
TKNWGWRLKEEKEKEGWLGFVFEC

Sequences:

>Translated_264_residues
MKELYKITLKNDLTLEQAWEILEENAFELAYGEEEESRGILYLYLNSVNEVSAYFWIKEIEKVQLPKIDWESQWALYGLD
FKNGSVHLSFDKFGRKAEPILLKPGPGFGDLSHPTTLLVLELMSQYLTTQSVIDIGSGSGVLTLAALALGASFAYGVDID
PAAIGHAQENAKFNQMESQCIFMLPEEFQFHSITVPLIVMNMIFSEQKIAWNALSSLHRLPGLRLISGIRQEERDVYFEQ
TKNWGWRLKEEKEKEGWLGFVFEC
>Mature_264_residues
MKELYKITLKNDLTLEQAWEILEENAFELAYGEEEESRGILYLYLNSVNEVSAYFWIKEIEKVQLPKIDWESQWALYGLD
FKNGSVHLSFDKFGRKAEPILLKPGPGFGDLSHPTTLLVLELMSQYLTTQSVIDIGSGSGVLTLAALALGASFAYGVDID
PAAIGHAQENAKFNQMESQCIFMLPEEFQFHSITVPLIVMNMIFSEQKIAWNALSSLHRLPGLRLISGIRQEERDVYFEQ
TKNWGWRLKEEKEKEGWLGFVFEC

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=145, Percent_Identity=37.9310344827586, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30184; Mature: 30184

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELYKITLKNDLTLEQAWEILEENAFELAYGEEEESRGILYLYLNSVNEVSAYFWIKEI
CCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHH
EKVQLPKIDWESQWALYGLDFKNGSVHLSFDKFGRKAEPILLKPGPGFGDLSHPTTLLVL
HHHCCCCCCCCCCEEEEEEEECCCEEEEEHHHCCCCCCCEEECCCCCCCCCCCCHHHHHH
ELMSQYLTTQSVIDIGSGSGVLTLAALALGASFAYGVDIDPAAIGHAQENAKFNQMESQC
HHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCHHHHHCCCE
IFMLPEEFQFHSITVPLIVMNMIFSEQKIAWNALSSLHRLPGLRLISGIRQEERDVYFEQ
EEECCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TKNWGWRLKEEKEKEGWLGFVFEC
CCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKELYKITLKNDLTLEQAWEILEENAFELAYGEEEESRGILYLYLNSVNEVSAYFWIKEI
CCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHH
EKVQLPKIDWESQWALYGLDFKNGSVHLSFDKFGRKAEPILLKPGPGFGDLSHPTTLLVL
HHHCCCCCCCCCCEEEEEEEECCCEEEEEHHHCCCCCCCEEECCCCCCCCCCCCHHHHHH
ELMSQYLTTQSVIDIGSGSGVLTLAALALGASFAYGVDIDPAAIGHAQENAKFNQMESQC
HHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCHHHHHCCCE
IFMLPEEFQFHSITVPLIVMNMIFSEQKIAWNALSSLHRLPGLRLISGIRQEERDVYFEQ
EEECCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TKNWGWRLKEEKEKEGWLGFVFEC
CCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA