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The map label for this gene is coaD

Identifier: 45659144

GI number: 45659144

Start: 4081061

End: 4081543

Strand: Direct

Name: coaD

Synonym: LIC13325

Alternate gene names: 45659144

Gene position: 4081061-4081543 (Clockwise)

Preceding gene: 45659143

Following gene: 45659145

Centisome position: 95.41

GC content: 35.82

Gene sequence:

>483_bases
ATGAAACACCTGGCAATTTATCCAGGCTCCTTTGATCCTCTTACAAAAGGTCATTTGGATATTCTTCAGAGATCTTTGGG
ACTTTTCGACAAAGTAATCATTGCGATTGCCGTCAATTCGAACAAGTCCACTTTATTTTCGATCGAAGAAAGACTTGGAT
TTATTCGTGAAGTTACAAAAGGTATGAAAGGTTTGGAAATCGATACCTTTCAAGGTCTTACCGTTGATTATTGTAATAAA
GTCGGAGCCAATAGTATCATTAGAGGACTTAGAGCCGTTACGGACTTTGATTACGAATATGCAATTTCTTTAATGAATAA
AAAATTGGCTCCAAATGTGGAAACCGTTTTTTTAATGTCTTCCGGAGAATATTCATTCATTTCTTCTACGATCGTAAAAG
AAGTAGCAAGACATGGAAGAGACGTAAGCAATCAGGTCCCAGAAATCGTAAGTAAAGCATTACTTAAAAAACTCTCTCAA
TAA

Upstream 100 bases:

>100_bases
CGACTTTCGAAAAAGAAGAATTATACAATCAGAAAGACGCCGAAGGTTTTATAAACATCTACGGCTTACCCGCTCAAGAA
ACGGCAAGGCTTCGCAAAAA

Downstream 100 bases:

>100_bases
GGAAAAAAAATGTCCAGAACGTTCATCATGATAAAACCAGACGGAGTTAAAAACAAACACGTCGGAAACATTCTCTCTAG
AATTGAAAAAGAAGGATTCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTKGMKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ

Sequences:

>Translated_160_residues
MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTKGMKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ
>Mature_160_residues
MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTKGMKGLEIDTFQGLTVDYCNK
VGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=47.1698113207547, Blast_Score=166, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17772; Mature: 17772

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTK
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHC
GMKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMS
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEC
SGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTK
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHC
GMKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMS
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEC
SGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA