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The map label for this gene is pheC [H]

Identifier: 45658357

GI number: 45658357

Start: 3043801

End: 3044793

Strand: Reverse

Name: pheC [H]

Synonym: LIC12515

Alternate gene names: 45658357

Gene position: 3044793-3043801 (Counterclockwise)

Preceding gene: 45658358

Following gene: 45658356

Centisome position: 71.19

GC content: 33.53

Gene sequence:

>993_bases
ATGAATTGGAAACATTTGTTTCTCATTAAAAAAAATATACAATATACTTTAGAAAAGAATTTATCTAGTAAGTTTTATTC
ACCATTCTACGTTTTAAACCGTTTTCAAATCAATCTGAAAAATGGAATTTGGAAAAGACTTGTTTTGATAGGCTCGTTTT
GCATTTTATACGGATATTTTTGCTTACAAGCAGAAGAAAATACATTCAAATATTATAATTCTTCTAGACTCAAAGAAATT
TTGGAAAAAGGAGAACTTAAAGTTGCAGGAGATCCTTCTTATGAACCGTTTTATATCCCAAATTCAAAAGAAGGGTATCC
GGGGTTTGATTACGAATTAGGAAAAGCCTACGCAGATTTTTTAGGAGTAAAGTATAAGTTTGTTTCTTATCCGGAGTTCA
ACGAGTTTGCAGAAGCAATTAAAAATAAAGAAGCGGATATTGCATTATCCGGAATTTCTAGTAATTTAGAAAGATCTAAA
AAACTAAAATTTAGTGGGGCTTATTTAGTAGCAACTCCGGCTGCTTTGATTCGAAAATCCGCTTTACCACCACCTCCGGA
AGGGAACATTATTACGACTCAAAGTTTCAGAAGTATTCTCGATTTGTCTGATTTGAGTGGAGTTACATTTGCAGTTCGAT
CTTTTTCCAATCGTCACGAGTATCTTTTAAAGAAGTTCAAAAACAATCGAATTTTTACCTATGTAGACACATCTTCCGCT
TGGGAAGCAGTCAAAAACGGAACCGCAAATTGTTTAGTCGCAGATTCATTTTATATCAAAAGTCTTATCCTTAAGGACAA
ATCGATCGCTTCTAATTTTAGGCCACTTTTGGAACCGGTGCAAAGAGAAGATATTAGTGCGGCTTTTCCTCAGGGGGACA
TTTTGTTTATTAGAAATTTTGAATTCTTTTTACAAGAGTTGAGTCGGACTGGAATTCTTAGGGAAATGGAAGATAAGTAT
TTTAATAAATCGGAATGGGTTCTTGCACCATAA

Upstream 100 bases:

>100_bases
AATTTTTTATTGCAAAACACTGTTTCAACGCAAAATACTGAGTATTTTATTTTATAATTCTTGAGTAAAAAAAGAAAACG
AATAAACAGGAGGAGCCGAA

Downstream 100 bases:

>100_bases
GTATTCATTACTATTAAGTAAAAAATTCATTTTATAGAGCCTTCTTTAAATAAAAACTAAAAAATACAATTATTTCCGAA
TCTAAAAAACTTTTTTAAAG

Product: cystine-binding periplasmic protein precursor

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNWKHLFLIKKNIQYTLEKNLSSKFYSPFYVLNRFQINLKNGIWKRLVLIGSFCILYGYFCLQAEENTFKYYNSSRLKEI
LEKGELKVAGDPSYEPFYIPNSKEGYPGFDYELGKAYADFLGVKYKFVSYPEFNEFAEAIKNKEADIALSGISSNLERSK
KLKFSGAYLVATPAALIRKSALPPPPEGNIITTQSFRSILDLSDLSGVTFAVRSFSNRHEYLLKKFKNNRIFTYVDTSSA
WEAVKNGTANCLVADSFYIKSLILKDKSIASNFRPLLEPVQREDISAAFPQGDILFIRNFEFFLQELSRTGILREMEDKY
FNKSEWVLAP

Sequences:

>Translated_330_residues
MNWKHLFLIKKNIQYTLEKNLSSKFYSPFYVLNRFQINLKNGIWKRLVLIGSFCILYGYFCLQAEENTFKYYNSSRLKEI
LEKGELKVAGDPSYEPFYIPNSKEGYPGFDYELGKAYADFLGVKYKFVSYPEFNEFAEAIKNKEADIALSGISSNLERSK
KLKFSGAYLVATPAALIRKSALPPPPEGNIITTQSFRSILDLSDLSGVTFAVRSFSNRHEYLLKKFKNNRIFTYVDTSSA
WEAVKNGTANCLVADSFYIKSLILKDKSIASNFRPLLEPVQREDISAAFPQGDILFIRNFEFFLQELSRTGILREMEDKY
FNKSEWVLAP
>Mature_330_residues
MNWKHLFLIKKNIQYTLEKNLSSKFYSPFYVLNRFQINLKNGIWKRLVLIGSFCILYGYFCLQAEENTFKYYNSSRLKEI
LEKGELKVAGDPSYEPFYIPNSKEGYPGFDYELGKAYADFLGVKYKFVSYPEFNEFAEAIKNKEADIALSGISSNLERSK
KLKFSGAYLVATPAALIRKSALPPPPEGNIITTQSFRSILDLSDLSGVTFAVRSFSNRHEYLLKKFKNNRIFTYVDTSSA
WEAVKNGTANCLVADSFYIKSLILKDKSIASNFRPLLEPVQREDISAAFPQGDILFIRNFEFFLQELSRTGILREMEDKY
FNKSEWVLAP

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=277, Percent_Identity=21.2996389891697, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 38010; Mature: 38010

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWKHLFLIKKNIQYTLEKNLSSKFYSPFYVLNRFQINLKNGIWKRLVLIGSFCILYGYF
CCCEEEEEEECCCHHHHHHCCHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHH
CLQAEENTFKYYNSSRLKEILEKGELKVAGDPSYEPFYIPNSKEGYPGFDYELGKAYADF
HEEECCCHHHHCCHHHHHHHHHCCCEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
LGVKYKFVSYPEFNEFAEAIKNKEADIALSGISSNLERSKKLKFSGAYLVATPAALIRKS
HCCEEEEECCCCHHHHHHHHCCCCCCEEEECHHHHHHHHHCEEECCEEEEECCHHHHHHC
ALPPPPEGNIITTQSFRSILDLSDLSGVTFAVRSFSNRHEYLLKKFKNNRIFTYVDTSSA
CCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEEECHHH
WEAVKNGTANCLVADSFYIKSLILKDKSIASNFRPLLEPVQREDISAAFPQGDILFIRNF
HHHHHCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
EFFLQELSRTGILREMEDKYFNKSEWVLAP
HHHHHHHHHHCHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MNWKHLFLIKKNIQYTLEKNLSSKFYSPFYVLNRFQINLKNGIWKRLVLIGSFCILYGYF
CCCEEEEEEECCCHHHHHHCCHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHH
CLQAEENTFKYYNSSRLKEILEKGELKVAGDPSYEPFYIPNSKEGYPGFDYELGKAYADF
HEEECCCHHHHCCHHHHHHHHHCCCEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
LGVKYKFVSYPEFNEFAEAIKNKEADIALSGISSNLERSKKLKFSGAYLVATPAALIRKS
HCCEEEEECCCCHHHHHHHHCCCCCCEEEECHHHHHHHHHCEEECCEEEEECCHHHHHHC
ALPPPPEGNIITTQSFRSILDLSDLSGVTFAVRSFSNRHEYLLKKFKNNRIFTYVDTSSA
CCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEEECHHH
WEAVKNGTANCLVADSFYIKSLILKDKSIASNFRPLLEPVQREDISAAFPQGDILFIRNF
HHHHHCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
EFFLQELSRTGILREMEDKYFNKSEWVLAP
HHHHHHHHHHCHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]