| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is crt
Identifier: 45658337
GI number: 45658337
Start: 3021213
End: 3021986
Strand: Reverse
Name: crt
Synonym: LIC12495
Alternate gene names: 45658337
Gene position: 3021986-3021213 (Counterclockwise)
Preceding gene: 45658338
Following gene: 45658336
Centisome position: 70.65
GC content: 39.41
Gene sequence:
>774_bases ATGAGTGAAAAATTAATCAATATAACTAAAGAAGGACAAATTGCAATTCTTACGATCCAAAGACCTTCCGCTTTGAATGC CCTCAATCGGGAAGTATTAATTCAGATCGGTCAAGAAGTGGATGCGCTTGAAAAAGATGAAAACATAAGAGTTTTAATTG TGACCGGTGAAGGTAAAGCGTTTGTTGCCGGAGCCGATATTGCCGAAATGAAAGACTTAAACGTTTCTCAGGGAAACGAG TTTTCTAAATTAGGAAATTCTGTATTCCAAAAATTGCATCAATCCAGAATCGTTTCGATTGCCGCGATCAATGGTTTTTC TCTTGGCGGAGGGTTAGAACTTGCTCTTGCCTGTGATATACGAGTCGGTTCTGAAAAAGCGAAGTTGGGTTTGCCGGAAG TTTCTCTGGGACTGATTCCAGGTTTTGGAGGCACACAAAGACTAGCCAGATTGATCGGTTATGCGAGAGCGATTGAGCTT GTAATAACCGGGGAAATGATTTCTGCGGAAGAAGGTTATAGAATCGGGATTCTTAATAAACTCGTAAAAGAGGGAGAAAG TATATTAGATTTTTCTAAATCGATTGCAAACTCGATCCTTAAAAAAGGACCTCAGGCGATCGAAAGAGTTAAAAAGACAA TCCAACAGGGTTTAGATGTTTCTTTAAAGGAAGGAATTTCTATAGAAGAAAAGGCGTTTGGAGACTGTTTTGACGGAGGG CAATCTAAAGAAGGTATGAGCGCGTTTTTGGAAAAAAGATCAGCTCAATTTTAA
Upstream 100 bases:
>100_bases TTTAAAGCAAACGTACAAAAAACGGTCGAAGATTTTTTTGGAAACGTAGCTTTAGAAGACGATACACTTTTTTTGATCGT GGAAGTGGAGTAAAATAGAA
Downstream 100 bases:
>100_bases GTGGTAGTTCCCACATTTTCGGAGTTAGGCTGTAAAATCTTGATTTGTGGTAGTTCCCACAAATTTGAAGTTAGACTGTA AAGTCTTGACTTGTGGTAGT
Product: 3-hydroxybutyryl-CoA dehydratase
Products: NA
Alternate protein names: Crotonase [H]
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MSEKLINITKEGQIAILTIQRPSALNALNREVLIQIGQEVDALEKDENIRVLIVTGEGKAFVAGADIAEMKDLNVSQGNE FSKLGNSVFQKLHQSRIVSIAAINGFSLGGGLELALACDIRVGSEKAKLGLPEVSLGLIPGFGGTQRLARLIGYARAIEL VITGEMISAEEGYRIGILNKLVKEGESILDFSKSIANSILKKGPQAIERVKKTIQQGLDVSLKEGISIEEKAFGDCFDGG QSKEGMSAFLEKRSAQF
Sequences:
>Translated_257_residues MSEKLINITKEGQIAILTIQRPSALNALNREVLIQIGQEVDALEKDENIRVLIVTGEGKAFVAGADIAEMKDLNVSQGNE FSKLGNSVFQKLHQSRIVSIAAINGFSLGGGLELALACDIRVGSEKAKLGLPEVSLGLIPGFGGTQRLARLIGYARAIEL VITGEMISAEEGYRIGILNKLVKEGESILDFSKSIANSILKKGPQAIERVKKTIQQGLDVSLKEGISIEEKAFGDCFDGG QSKEGMSAFLEKRSAQF >Mature_256_residues SEKLINITKEGQIAILTIQRPSALNALNREVLIQIGQEVDALEKDENIRVLIVTGEGKAFVAGADIAEMKDLNVSQGNEF SKLGNSVFQKLHQSRIVSIAAINGFSLGGGLELALACDIRVGSEKAKLGLPEVSLGLIPGFGGTQRLARLIGYARAIELV ITGEMISAEEGYRIGILNKLVKEGESILDFSKSIANSILKKGPQAIERVKKTIQQGLDVSLKEGISIEEKAFGDCFDGGQ SKEGMSAFLEKRSAQF
Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=36.6935483870968, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI4502327, Length=248, Percent_Identity=36.2903225806452, Blast_Score=132, Evalue=3e-31, Organism=Homo sapiens, GI20127408, Length=188, Percent_Identity=35.1063829787234, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI68989263, Length=274, Percent_Identity=28.8321167883212, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI150378541, Length=248, Percent_Identity=30.6451612903226, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI213417737, Length=246, Percent_Identity=25.609756097561, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI157694516, Length=246, Percent_Identity=25.609756097561, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI70995211, Length=230, Percent_Identity=27.3913043478261, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI31542718, Length=241, Percent_Identity=27.8008298755187, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI157694520, Length=219, Percent_Identity=23.7442922374429, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI261878539, Length=182, Percent_Identity=31.3186813186813, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI37594471, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI37594469, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI62530384, Length=206, Percent_Identity=26.2135922330097, Blast_Score=80, Evalue=2e-15, Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=36.2934362934363, Blast_Score=174, Evalue=4e-45, Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=33.5106382978723, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI1788682, Length=276, Percent_Identity=32.9710144927536, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=31.6793893129771, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=31.4393939393939, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=27.037037037037, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1788597, Length=254, Percent_Identity=26.7716535433071, Blast_Score=76, Evalue=3e-15, Organism=Caenorhabditis elegans, GI25145438, Length=260, Percent_Identity=37.3076923076923, Blast_Score=181, Evalue=3e-46, Organism=Caenorhabditis elegans, GI17554946, Length=265, Percent_Identity=35.4716981132075, Blast_Score=170, Evalue=5e-43, Organism=Caenorhabditis elegans, GI17540714, Length=226, Percent_Identity=37.1681415929204, Blast_Score=151, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=35.9116022099448, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI25144276, Length=181, Percent_Identity=38.121546961326, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17508951, Length=181, Percent_Identity=38.121546961326, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17508953, Length=181, Percent_Identity=38.121546961326, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17534483, Length=238, Percent_Identity=26.890756302521, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560910, Length=195, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17536985, Length=226, Percent_Identity=29.2035398230088, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI25141363, Length=192, Percent_Identity=27.6041666666667, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI25144160, Length=190, Percent_Identity=28.4210526315789, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI25144157, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17540306, Length=263, Percent_Identity=25.0950570342205, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=21.6535433070866, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17549921, Length=238, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=185, Percent_Identity=27.5675675675676, Blast_Score=79, Evalue=6e-16, Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=37.5, Blast_Score=176, Evalue=2e-44, Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=37.5, Blast_Score=176, Evalue=2e-44, Organism=Drosophila melanogaster, GI24653139, Length=248, Percent_Identity=34.6774193548387, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=27.6018099547511, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=26.530612244898, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24650670, Length=187, Percent_Identity=31.5508021390374, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21357171, Length=190, Percent_Identity=31.5789473684211, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI19921000, Length=174, Percent_Identity=37.3563218390805, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24583077, Length=174, Percent_Identity=37.3563218390805, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24583079, Length=174, Percent_Identity=37.3563218390805, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24654903, Length=205, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI28571729, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI28571730, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI19921018, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24583165, Length=193, Percent_Identity=26.4248704663212, Blast_Score=74, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.55 [H]
Molecular weight: Translated: 27587; Mature: 27456
Theoretical pI: Translated: 5.52; Mature: 5.52
Prosite motif: PS00879 ODR_DC_2_2 ; PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEKLINITKEGQIAILTIQRPSALNALNREVLIQIGQEVDALEKDENIRVLIVTGEGKA CCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE FVAGADIAEMKDLNVSQGNEFSKLGNSVFQKLHQSRIVSIAAINGFSLGGGLELALACDI EEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCEECCCCEEEEEEEEE RVGSEKAKLGLPEVSLGLIPGFGGTQRLARLIGYARAIELVITGEMISAEEGYRIGILNK EECCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEECCEECCCCCCEEHHHHH LVKEGESILDFSKSIANSILKKGPQAIERVKKTIQQGLDVSLKEGISIEEKAFGDCFDGG HHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEHHCCCCCCHHHCCCCCCCC QSKEGMSAFLEKRSAQF CCCHHHHHHHHHHCCCC >Mature Secondary Structure SEKLINITKEGQIAILTIQRPSALNALNREVLIQIGQEVDALEKDENIRVLIVTGEGKA CCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE FVAGADIAEMKDLNVSQGNEFSKLGNSVFQKLHQSRIVSIAAINGFSLGGGLELALACDI EEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCEECCCCEEEEEEEEE RVGSEKAKLGLPEVSLGLIPGFGGTQRLARLIGYARAIELVITGEMISAEEGYRIGILNK EECCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEECCEECCCCCCEEHHHHH LVKEGESILDFSKSIANSILKKGPQAIERVKKTIQQGLDVSLKEGISIEEKAFGDCFDGG HHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEHHCCCCCCHHHCCCCCCCC QSKEGMSAFLEKRSAQF CCCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8655474; 11466286 [H]