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The map label for this gene is gmhA [H]

Identifier: 45658052

GI number: 45658052

Start: 2656538

End: 2657095

Strand: Reverse

Name: gmhA [H]

Synonym: LIC12203

Alternate gene names: 45658052

Gene position: 2657095-2656538 (Counterclockwise)

Preceding gene: 45658053

Following gene: 45658051

Centisome position: 62.12

GC content: 38.89

Gene sequence:

>558_bases
ATGTTAGATCATTACAATGCCTATATAGGCCGTCTTCAATCCGTTCTTGTTCCCGAAAGAGCATCAGAAATAGAACGCCT
TGCACTTTCATTGAAAGATGCTTGGGAGACTAAAAAACAAGTTTTCCTTTGTGGAAACGGTGGAAGTGCCGGAAATGCAA
TTCATCTCGCAAATGATTTTAATTACGGTATCGATAAAAAAAATGGAATGGGACTTCGTGTGGAAGCTTTACCTGCGAAC
GCTGCCGTCATTACTTGCCTTGCCAATGACGAAGGATACGATACAATTTTTTCTCAACAATTAGAGGTAAAGGCGAATAA
AGGTGATGTTCTAATCGTCCTTTCTGGAAGTGGTAATTCACCTAACGTAGTAAAGGCGCTCGAAGTAGGAAATAAGTTAG
AAATGATTACATATGCGATTTTGGGATTTTCGGGAGGTAAATGTAAGGAATTGGCGAAATATCCAATTCACTTTCCGATC
AATGATATGCAAATCTCTGAAGATTTACAAGTAATTGTAGGCCATATGTGTATGCAATGGTTGTGTGGAGCAAAGTAA

Upstream 100 bases:

>100_bases
AGTCCCGGACTTACTTCTTCTCCTTCGATTGGCGAAGAAGTGTTTCTATTAGTCAAATCGCTGATTTAGTAATTTTTTCT
TTATGTAAGAGGAAAAGCAG

Downstream 100 bases:

>100_bases
AATAAAATGAAAGCGTTAGTTACAGGCGGAGCAGGGTTTATTGGAAGTCATCTTGTAGATCTTCTATTGGAAAATCAATT
TGAGGTTACCGTTCTGGATA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLDHYNAYIGRLQSVLVPERASEIERLALSLKDAWETKKQVFLCGNGGSAGNAIHLANDFNYGIDKKNGMGLRVEALPAN
AAVITCLANDEGYDTIFSQQLEVKANKGDVLIVLSGSGNSPNVVKALEVGNKLEMITYAILGFSGGKCKELAKYPIHFPI
NDMQISEDLQVIVGHMCMQWLCGAK

Sequences:

>Translated_185_residues
MLDHYNAYIGRLQSVLVPERASEIERLALSLKDAWETKKQVFLCGNGGSAGNAIHLANDFNYGIDKKNGMGLRVEALPAN
AAVITCLANDEGYDTIFSQQLEVKANKGDVLIVLSGSGNSPNVVKALEVGNKLEMITYAILGFSGGKCKELAKYPIHFPI
NDMQISEDLQVIVGHMCMQWLCGAK
>Mature_185_residues
MLDHYNAYIGRLQSVLVPERASEIERLALSLKDAWETKKQVFLCGNGGSAGNAIHLANDFNYGIDKKNGMGLRVEALPAN
AAVITCLANDEGYDTIFSQQLEVKANKGDVLIVLSGSGNSPNVVKALEVGNKLEMITYAILGFSGGKCKELAKYPIHFPI
NDMQISEDLQVIVGHMCMQWLCGAK

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=161, Percent_Identity=34.7826086956522, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789539, Length=124, Percent_Identity=33.0645161290323, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20103; Mature: 20103

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDHYNAYIGRLQSVLVPERASEIERLALSLKDAWETKKQVFLCGNGGSAGNAIHLANDF
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCC
NYGIDKKNGMGLRVEALPANAAVITCLANDEGYDTIFSQQLEVKANKGDVLIVLSGSGNS
CCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHCCEEEEEECCCCEEEEEECCCCC
PNVVKALEVGNKLEMITYAILGFSGGKCKELAKYPIHFPINDMQISEDLQVIVGHMCMQW
CCEEEEECCCCHHHEEEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LCGAK
HHCCC
>Mature Secondary Structure
MLDHYNAYIGRLQSVLVPERASEIERLALSLKDAWETKKQVFLCGNGGSAGNAIHLANDF
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCC
NYGIDKKNGMGLRVEALPANAAVITCLANDEGYDTIFSQQLEVKANKGDVLIVLSGSGNS
CCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHCCEEEEEECCCCEEEEEECCCCC
PNVVKALEVGNKLEMITYAILGFSGGKCKELAKYPIHFPINDMQISEDLQVIVGHMCMQW
CCEEEEECCCCHHHEEEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LCGAK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA