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The map label for this gene is 45657684

Identifier: 45657684

GI number: 45657684

Start: 2212588

End: 2214492

Strand: Reverse

Name: 45657684

Synonym: LIC11819

Alternate gene names: NA

Gene position: 2214492-2212588 (Counterclockwise)

Preceding gene: 45657685

Following gene: 45657682

Centisome position: 51.77

GC content: 36.12

Gene sequence:

>1905_bases
TTGAAGGATAGAAATTTTTCTGATTCTATTTCTGAGTTAGAGTTTGTTAAAACCGAACTCGAAAGAGAAAAGAAAGAAGA
AGATTCTATTTTTTCAAAAGACTGGTTATCACGTCCGATTCCGGATAGAGTTCGACAAGGAATCACTTTATATCCTATTG
TTTACGAAGAACAAACTCTGGGAAGAGAAGGAAATTGGATTTTAACCTTTCGATTTTCCAATCAAGAAGAATATCCTATA
AAGTTTCAAACCGGCGCCCCGGTTCAATTTGGTAAAAATGAAGATCGAGCTAAAGCTATATTAGTTTCTCTTCATAAAGA
AAAAATTAAAATTTCGATCGAAGAGGTTCCGGAATGGGCAGAAGAAGGAAAATGTTTTTTAGATCTTTTGCCGGATGAAA
CTTCTTACAAAGAGATGTTTAACGCATTAGACGCTGTTAGATTGGCGACTAAAGGAACAAGATTGTATGTAAATCGAGAA
CTTCTTTTGGGTTATGGAAAACCGGATTTGATTTCAACTCGAGATTCCGATCGTTCTCGTATCTTGGGAAGAATTAGTAC
GTCTTTGAACGAATCTCAAAAAAATGCAGTTATACATTCAGTTTTATCTGAGGACGTAATGATTATTCACGGACCACCGG
GTACAGGCAAAACAACTACATTAACTGAAATTGTAAGCCAACTCGTTGCAGAAGAAAAAAAGATATTAGTATCTGCTCCT
ACAAATTCTGCTTGTGATCTTCTTGTTGAATCAATTTCGGCAAGAGGAATTCTAGTTTTAAGACTTGGTCATCCGGCTCG
GATCAACGAAATCGCAATCCATTCTACCTTAGATTATAAACTATTTCACCATCCAGACGGAAAATTATTAAACGAATATA
GGAAAGACGTAATCGAAATTTCAAAACAGGCCAAAAAATTTAAACGGAATTTTGGCGAAAAAGAAAGAGAAGAACGAAAA
AAACTTTTTACAGAAGTGAAGGAACTTAAAAAAACGATTCGTTCTATGGAAATAGGGCTGATAGATAGTTTGGTTTCTTC
TCATCCTGTAATCGTTTCTACCCCGGTTGCTTCGGCCCGAGGTATTTTAGAAAATAGAACGTTCGACTTTTGTGTGTTAG
ACGAATCCTCTCAGGCTTTGGAACCAGCTTTTTGGATTCCGATTTTAAAATCGGATCGTGTGATTCTCGCAGGAGATCAC
AAACAATTACCTCCTACTTTATTTTCTGAAAAAAATTATCTTGAAACTACACTTTTTGAAAAAGCTGTTGAGAATTTAGA
ATTGTACGGACGCGTTTTTTTACTCGATACACAATACAGAATGAAAGATGAAATATCTGCTTTTCCTTCGAAAGAATTTT
ATTCGGGTCTTTTAAAATCGGGGCGTTCTGAAAAAGAAAGGAAGTCTAACTTTCCAAAAACATTCCCTTTTTTGAATGCG
TTTCAGTGGATCGATACTTCTGGAACCGATAGTGAGGAAGTTATTCTAGATGATAGTATTTCCAATCCATTTGAAGCGGA
TTTGCAGGTGCGTCTTTGTTTTCTTTTAAAGGAAAACGACTGGCCAGAAGATGAGATTACGATTCTTTCTCCTTATCGCG
CTCAAGTTCGATTGATTTCTGAAAAACTAAGAGATGTAGGACTTACAAAAATCAACGTTTCTACAATCGATTCGTTTCAG
GGAAGGGAGAATCGTTGCATTTTACTTGGTTTTGTACGTTCTAATTTGGAAGGTCGTTCCGGTTTTTTAAAAGAATCGAG
AAGGATCAACGTAGGTATGGCTAGAGCCAGGGATCTTTTACTTTGTATCGGTGATAGTTCCACACTTTCACAAGATCCTT
TTTTATCGAAACTTATTCGATTTGCAGAAGAAAAAGAAGTATTTAGGACTGCTTGGGAATTCTAA

Upstream 100 bases:

>100_bases
CAACTCTTGCTAGTGCGATTCGATTTGCGGAAGGTCTTTCTATCAAAGAAGATTCAAAATCACAGGTCTACAGAATTGTA
GTCCTATCCCCTGATCGGTT

Downstream 100 bases:

>100_bases
GCGTTTACTAAGAGTTAGGTTTATTTTTTGGATATAATGTAATCTTGATATAGTAGATTCGTTTTATAAATCCTGATTTT
TCTGTAAAAATGAAATGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MKDRNFSDSISELEFVKTELEREKKEEDSIFSKDWLSRPIPDRVRQGITLYPIVYEEQTLGREGNWILTFRFSNQEEYPI
KFQTGAPVQFGKNEDRAKAILVSLHKEKIKISIEEVPEWAEEGKCFLDLLPDETSYKEMFNALDAVRLATKGTRLYVNRE
LLLGYGKPDLISTRDSDRSRILGRISTSLNESQKNAVIHSVLSEDVMIIHGPPGTGKTTTLTEIVSQLVAEEKKILVSAP
TNSACDLLVESISARGILVLRLGHPARINEIAIHSTLDYKLFHHPDGKLLNEYRKDVIEISKQAKKFKRNFGEKEREERK
KLFTEVKELKKTIRSMEIGLIDSLVSSHPVIVSTPVASARGILENRTFDFCVLDESSQALEPAFWIPILKSDRVILAGDH
KQLPPTLFSEKNYLETTLFEKAVENLELYGRVFLLDTQYRMKDEISAFPSKEFYSGLLKSGRSEKERKSNFPKTFPFLNA
FQWIDTSGTDSEEVILDDSISNPFEADLQVRLCFLLKENDWPEDEITILSPYRAQVRLISEKLRDVGLTKINVSTIDSFQ
GRENRCILLGFVRSNLEGRSGFLKESRRINVGMARARDLLLCIGDSSTLSQDPFLSKLIRFAEEKEVFRTAWEF

Sequences:

>Translated_634_residues
MKDRNFSDSISELEFVKTELEREKKEEDSIFSKDWLSRPIPDRVRQGITLYPIVYEEQTLGREGNWILTFRFSNQEEYPI
KFQTGAPVQFGKNEDRAKAILVSLHKEKIKISIEEVPEWAEEGKCFLDLLPDETSYKEMFNALDAVRLATKGTRLYVNRE
LLLGYGKPDLISTRDSDRSRILGRISTSLNESQKNAVIHSVLSEDVMIIHGPPGTGKTTTLTEIVSQLVAEEKKILVSAP
TNSACDLLVESISARGILVLRLGHPARINEIAIHSTLDYKLFHHPDGKLLNEYRKDVIEISKQAKKFKRNFGEKEREERK
KLFTEVKELKKTIRSMEIGLIDSLVSSHPVIVSTPVASARGILENRTFDFCVLDESSQALEPAFWIPILKSDRVILAGDH
KQLPPTLFSEKNYLETTLFEKAVENLELYGRVFLLDTQYRMKDEISAFPSKEFYSGLLKSGRSEKERKSNFPKTFPFLNA
FQWIDTSGTDSEEVILDDSISNPFEADLQVRLCFLLKENDWPEDEITILSPYRAQVRLISEKLRDVGLTKINVSTIDSFQ
GRENRCILLGFVRSNLEGRSGFLKESRRINVGMARARDLLLCIGDSSTLSQDPFLSKLIRFAEEKEVFRTAWEF
>Mature_634_residues
MKDRNFSDSISELEFVKTELEREKKEEDSIFSKDWLSRPIPDRVRQGITLYPIVYEEQTLGREGNWILTFRFSNQEEYPI
KFQTGAPVQFGKNEDRAKAILVSLHKEKIKISIEEVPEWAEEGKCFLDLLPDETSYKEMFNALDAVRLATKGTRLYVNRE
LLLGYGKPDLISTRDSDRSRILGRISTSLNESQKNAVIHSVLSEDVMIIHGPPGTGKTTTLTEIVSQLVAEEKKILVSAP
TNSACDLLVESISARGILVLRLGHPARINEIAIHSTLDYKLFHHPDGKLLNEYRKDVIEISKQAKKFKRNFGEKEREERK
KLFTEVKELKKTIRSMEIGLIDSLVSSHPVIVSTPVASARGILENRTFDFCVLDESSQALEPAFWIPILKSDRVILAGDH
KQLPPTLFSEKNYLETTLFEKAVENLELYGRVFLLDTQYRMKDEISAFPSKEFYSGLLKSGRSEKERKSNFPKTFPFLNA
FQWIDTSGTDSEEVILDDSISNPFEADLQVRLCFLLKENDWPEDEITILSPYRAQVRLISEKLRDVGLTKINVSTIDSFQ
GRENRCILLGFVRSNLEGRSGFLKESRRINVGMARARDLLLCIGDSSTLSQDPFLSKLIRFAEEKEVFRTAWEF

Specific function: Unknown

COG id: COG1112

COG function: function code L; Superfamily I DNA and RNA helicases and helicase subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA2/NAM7 helicase family [H]

Homologues:

Organism=Homo sapiens, GI119392094, Length=647, Percent_Identity=32.1483771251932, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI18375673, Length=516, Percent_Identity=30.6201550387597, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI122937299, Length=493, Percent_Identity=27.789046653144, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI113722133, Length=563, Percent_Identity=27.5310834813499, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI254826809, Length=460, Percent_Identity=28.2608695652174, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI156105693, Length=509, Percent_Identity=27.5049115913556, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI156105695, Length=509, Percent_Identity=27.7013752455796, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI14251207, Length=511, Percent_Identity=27.7886497064579, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI255759908, Length=492, Percent_Identity=28.0487804878049, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI28626521, Length=285, Percent_Identity=29.8245614035088, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI194272168, Length=491, Percent_Identity=26.8839103869654, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI14211540, Length=491, Percent_Identity=26.8839103869654, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI255759910, Length=302, Percent_Identity=30.1324503311258, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI54792138, Length=471, Percent_Identity=22.5053078556263, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17510163, Length=525, Percent_Identity=29.3333333333333, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17533987, Length=466, Percent_Identity=29.1845493562232, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17533985, Length=466, Percent_Identity=29.1845493562232, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71981659, Length=470, Percent_Identity=27.4468085106383, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17538027, Length=274, Percent_Identity=27.7372262773723, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17531515, Length=304, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17531513, Length=302, Percent_Identity=28.1456953642384, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71986364, Length=282, Percent_Identity=28.0141843971631, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322835, Length=486, Percent_Identity=33.9506172839506, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323726, Length=453, Percent_Identity=31.7880794701987, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6321958, Length=467, Percent_Identity=27.6231263383298, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321024, Length=510, Percent_Identity=29.4117647058824, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323462, Length=536, Percent_Identity=27.9850746268657, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859757, Length=460, Percent_Identity=32.1739130434783, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24649577, Length=446, Percent_Identity=30.9417040358744, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI161077698, Length=487, Percent_Identity=25.6673511293634, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24640932, Length=487, Percent_Identity=25.6673511293634, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24660647, Length=498, Percent_Identity=24.8995983935743, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221330969, Length=498, Percent_Identity=24.8995983935743, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281363531, Length=438, Percent_Identity=26.7123287671233, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281363529, Length=438, Percent_Identity=26.7123287671233, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI62471854, Length=491, Percent_Identity=25.8655804480652, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24656854, Length=491, Percent_Identity=25.8655804480652, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550425, Length=300, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45553113, Length=497, Percent_Identity=25.5533199195171, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR004483 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 72598; Mature: 72598

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRNFSDSISELEFVKTELEREKKEEDSIFSKDWLSRPIPDRVRQGITLYPIVYEEQTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEEECHHHC
GREGNWILTFRFSNQEEYPIKFQTGAPVQFGKNEDRAKAILVSLHKEKIKISIEEVPEWA
CCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEHHHEEEEHHHHHCHH
EEGKCFLDLLPDETSYKEMFNALDAVRLATKGTRLYVNRELLLGYGKPDLISTRDSDRSR
HCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCHHHH
ILGRISTSLNESQKNAVIHSVLSEDVMIIHGPPGTGKTTTLTEIVSQLVAEEKKILVSAP
HHHHHHHHHCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECC
TNSACDLLVESISARGILVLRLGHPARINEIAIHSTLDYKLFHHPDGKLLNEYRKDVIEI
CCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECEEEEECCCHHHHHHHHHHHHHH
SKQAKKFKRNFGEKEREERKKLFTEVKELKKTIRSMEIGLIDSLVSSHPVIVSTPVASAR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
GILENRTFDFCVLDESSQALEPAFWIPILKSDRVILAGDHKQLPPTLFSEKNYLETTLFE
HHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHCCCCHHHHHHHH
KAVENLELYGRVFLLDTQYRMKDEISAFPSKEFYSGLLKSGRSEKERKSNFPKTFPFLNA
HHHHHHHHEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCHHHH
FQWIDTSGTDSEEVILDDSISNPFEADLQVRLCFLLKENDWPEDEITILSPYRAQVRLIS
HHHCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCHHHHHHHHH
EKLRDVGLTKINVSTIDSFQGRENRCILLGFVRSNLEGRSGFLKESRRINVGMARARDLL
HHHHHCCCEEEEEEHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCHHCCCEEE
LCIGDSSTLSQDPFLSKLIRFAEEKEVFRTAWEF
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDRNFSDSISELEFVKTELEREKKEEDSIFSKDWLSRPIPDRVRQGITLYPIVYEEQTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEEECHHHC
GREGNWILTFRFSNQEEYPIKFQTGAPVQFGKNEDRAKAILVSLHKEKIKISIEEVPEWA
CCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEHHHEEEEHHHHHCHH
EEGKCFLDLLPDETSYKEMFNALDAVRLATKGTRLYVNRELLLGYGKPDLISTRDSDRSR
HCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCHHHH
ILGRISTSLNESQKNAVIHSVLSEDVMIIHGPPGTGKTTTLTEIVSQLVAEEKKILVSAP
HHHHHHHHHCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECC
TNSACDLLVESISARGILVLRLGHPARINEIAIHSTLDYKLFHHPDGKLLNEYRKDVIEI
CCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECEEEEECCCHHHHHHHHHHHHHH
SKQAKKFKRNFGEKEREERKKLFTEVKELKKTIRSMEIGLIDSLVSSHPVIVSTPVASAR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
GILENRTFDFCVLDESSQALEPAFWIPILKSDRVILAGDHKQLPPTLFSEKNYLETTLFE
HHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHCCCCHHHHHHHH
KAVENLELYGRVFLLDTQYRMKDEISAFPSKEFYSGLLKSGRSEKERKSNFPKTFPFLNA
HHHHHHHHEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCHHHH
FQWIDTSGTDSEEVILDDSISNPFEADLQVRLCFLLKENDWPEDEITILSPYRAQVRLIS
HHHCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCHHHHHHHHH
EKLRDVGLTKINVSTIDSFQGRENRCILLGFVRSNLEGRSGFLKESRRINVGMARARDLL
HHHHHCCCEEEEEEHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCHHCCCEEE
LCIGDSSTLSQDPFLSKLIRFAEEKEVFRTAWEF
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]