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The map label for this gene is argC

Identifier: 45657612

GI number: 45657612

Start: 2131858

End: 2132874

Strand: Direct

Name: argC

Synonym: LIC11746

Alternate gene names: 45657612

Gene position: 2131858-2132874 (Clockwise)

Preceding gene: 45657611

Following gene: 45657613

Centisome position: 49.84

GC content: 34.61

Gene sequence:

>1017_bases
ATGGCAGAGATTAGTATTTTAGGAGCTGGGGGATTAACCGGAAAGGAATTACTTTTACTTTTCTCCCGCCAAAAAGAACA
TGAAGTAGTTCATATAACAAGCGATAAACTTGCAGGTAAAACAATTTCAGAAGTTTTTCCCGAAGTGTCGTTTCCCAAAA
ATCTAGTTTTTAAAAAACACGAAGATATTGTTCCTCTAAAATCTTTAGTCGTACTTGCAGTTCCTAATGAAGTTTCTGTG
GAATCTGCTCCTAAGTTTTTAGACGCTGGACATAAGGTCATAGACCTTTCTGGAGTTTACAGACTTCATAATCAAGAAAT
ATTAGAAAAATATTATAAACTAAAACATACTCGTTTTAATTATATAAACAGGGCAGTATTTGGTATTCCTGAAATTTTCA
GAGATCAATTGAAAAACGCGGATTTTGTTTCTAATCCTGGATGTTTTTCTACCTCTGTGATTTTACCTATATTTTTACTA
GGTCAACTTAGAAAAAATCTTAGACCTAGAATTATAGTCGATTCCAAATCAGGGGTTTCTGGCGCAGGAGGAAGGACAGA
AGATTCAGGTTATTCTTATACAAGCGTATATGAAAATTTTAGAGCATATAAAATTCTTTCCCACCAACACGAACCGGAAA
TCCGGGAATATGTTTATTCTAAATCTGGACTTTCCGATCCGGAGGTAATTTTTACTCCTCATTTACTTCCTGTTTATAGA
GGGATTCTTTCCACAATCGTATTAGAATTTGATTCTGAACCAGAGCAAGATCTTATTTCTATTTTAGAAAACTCTTCTTT
AAATGAACCTTTTATTCGTATTTTAAAAACTCCCGAAGAGATTGAATTAAAAAAGGTGCAACATACAAATTTTCTAGACA
TTTCGCTTCGTAAAAGAGGAAACACGTTAGTCGTTGTTTCTGCACTGGATAATCTAGTAAAAGGTGCCGCGGGTCAGGCT
TTACAAAACATCAATTTAATGACTGGAGCCAAAGAAACCTTGGGGTTACTTCCCTAA

Upstream 100 bases:

>100_bases
CGGGAGTTCTCACATTTTTTTAAAGAATTTTGTTTTTGTGTGAGTTCCTACATCCTCAAGGTTTAGTACAAAATTCTAAA
TAACGATTATAGTTAGGATT

Downstream 100 bases:

>100_bases
TCTCTATGGAAAAAACAAGTCTATATCATCTAATCAGAGACGTAGCTTCCGTTTATTCGGATAGGCCCATGTATTGGATT
CGAGAAGAATCCGGAGATTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAEISILGAGGLTGKELLLLFSRQKEHEVVHITSDKLAGKTISEVFPEVSFPKNLVFKKHEDIVPLKSLVVLAVPNEVSV
ESAPKFLDAGHKVIDLSGVYRLHNQEILEKYYKLKHTRFNYINRAVFGIPEIFRDQLKNADFVSNPGCFSTSVILPIFLL
GQLRKNLRPRIIVDSKSGVSGAGGRTEDSGYSYTSVYENFRAYKILSHQHEPEIREYVYSKSGLSDPEVIFTPHLLPVYR
GILSTIVLEFDSEPEQDLISILENSSLNEPFIRILKTPEEIELKKVQHTNFLDISLRKRGNTLVVVSALDNLVKGAAGQA
LQNINLMTGAKETLGLLP

Sequences:

>Translated_338_residues
MAEISILGAGGLTGKELLLLFSRQKEHEVVHITSDKLAGKTISEVFPEVSFPKNLVFKKHEDIVPLKSLVVLAVPNEVSV
ESAPKFLDAGHKVIDLSGVYRLHNQEILEKYYKLKHTRFNYINRAVFGIPEIFRDQLKNADFVSNPGCFSTSVILPIFLL
GQLRKNLRPRIIVDSKSGVSGAGGRTEDSGYSYTSVYENFRAYKILSHQHEPEIREYVYSKSGLSDPEVIFTPHLLPVYR
GILSTIVLEFDSEPEQDLISILENSSLNEPFIRILKTPEEIELKKVQHTNFLDISLRKRGNTLVVVSALDNLVKGAAGQA
LQNINLMTGAKETLGLLP
>Mature_337_residues
AEISILGAGGLTGKELLLLFSRQKEHEVVHITSDKLAGKTISEVFPEVSFPKNLVFKKHEDIVPLKSLVVLAVPNEVSVE
SAPKFLDAGHKVIDLSGVYRLHNQEILEKYYKLKHTRFNYINRAVFGIPEIFRDQLKNADFVSNPGCFSTSVILPIFLLG
QLRKNLRPRIIVDSKSGVSGAGGRTEDSGYSYTSVYENFRAYKILSHQHEPEIREYVYSKSGLSDPEVIFTPHLLPVYRG
ILSTIVLEFDSEPEQDLISILENSSLNEPFIRILKTPEEIELKKVQHTNFLDISLRKRGNTLVVVSALDNLVKGAAGQAL
QNINLMTGAKETLGLLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=347, Percent_Identity=33.1412103746398, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320913, Length=354, Percent_Identity=27.9661016949153, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_LEPIC (Q72RJ9)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001698.1
- ProteinModelPortal:   Q72RJ9
- SMR:   Q72RJ9
- GeneID:   2771378
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11746
- NMPDR:   fig|267671.1.peg.1698
- HOGENOM:   HBG294213
- OMA:   HEPEIRE
- ProtClustDB:   PRK00436
- BioCyc:   LINT267671:LIC_11746-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37782; Mature: 37651

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEISILGAGGLTGKELLLLFSRQKEHEVVHITSDKLAGKTISEVFPEVSFPKNLVFKKH
CCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHCCC
EDIVPLKSLVVLAVPNEVSVESAPKFLDAGHKVIDLSGVYRLHNQEILEKYYKLKHTRFN
CCCCCCCCEEEEECCCCCCHHHCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
YINRAVFGIPEIFRDQLKNADFVSNPGCFSTSVILPIFLLGQLRKNLRPRIIVDSKSGVS
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GAGGRTEDSGYSYTSVYENFRAYKILSHQHEPEIREYVYSKSGLSDPEVIFTPHLLPVYR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCHHHHHH
GILSTIVLEFDSEPEQDLISILENSSLNEPFIRILKTPEEIELKKVQHTNFLDISLRKRG
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCEEEEEEECCC
NTLVVVSALDNLVKGAAGQALQNINLMTGAKETLGLLP
CEEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHHCCCC
>Mature Secondary Structure 
AEISILGAGGLTGKELLLLFSRQKEHEVVHITSDKLAGKTISEVFPEVSFPKNLVFKKH
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHCCC
EDIVPLKSLVVLAVPNEVSVESAPKFLDAGHKVIDLSGVYRLHNQEILEKYYKLKHTRFN
CCCCCCCCEEEEECCCCCCHHHCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
YINRAVFGIPEIFRDQLKNADFVSNPGCFSTSVILPIFLLGQLRKNLRPRIIVDSKSGVS
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GAGGRTEDSGYSYTSVYENFRAYKILSHQHEPEIREYVYSKSGLSDPEVIFTPHLLPVYR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCHHHHHH
GILSTIVLEFDSEPEQDLISILENSSLNEPFIRILKTPEEIELKKVQHTNFLDISLRKRG
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCEEEEEEECCC
NTLVVVSALDNLVKGAAGQALQNINLMTGAKETLGLLP
CEEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA