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The map label for this gene is ydiD

Identifier: 45657613

GI number: 45657613

Start: 2132880

End: 2134817

Strand: Direct

Name: ydiD

Synonym: LIC11747

Alternate gene names: 45657613

Gene position: 2132880-2134817 (Clockwise)

Preceding gene: 45657612

Following gene: 45657614

Centisome position: 49.87

GC content: 37.05

Gene sequence:

>1938_bases
ATGGAAAAAACAAGTCTATATCATCTAATCAGAGACGTAGCTTCCGTTTATTCGGATAGGCCCATGTATTGGATTCGAGA
AGAATCCGGAGATTTTAGAGGAATCTCTTATAAAGATTGGTATGAAAATCTAAAAAATCTTTCTACATTTCTAATCGATC
TAGGAATGCACAAAGGAAATACGGCCGGACTTATCTGTGATAATCGATACGAATGGTCTCTGTGTTCCCTTTCGTTAGTT
ACGATTGGATGTGTAGATGTACCTCGCGGGTGCGACGCGACAATAGAAGATCTGAAATATATATTAGAACATTCTGAAGC
TAAGATTCTTTTTTTAGAAAATGAGAAAGTACTAAAGAAGTTATTAGAAAATAAATCCAGTCTTGCCAAAGTGAAAACGA
TTCTTCTTATAGACCCTCCTACAAAATGGAAAGACTTAGAAAATTCTCGCGCATTACTTTCCGGAATCCAATTTTTATTT
TTAGAAGACGCACTTTTGGAAGGAGAAAAATCTAGAATCAAAAAGGGAGATAAAACTTATGATCAAAGAGGTGAATCTTT
AGGCGGAAAAGATTTAGCAACGATCATTTATACTTCTGGAACAACGGGTGCTCCGAAAGGTGTAATGTTAAATCATAGAA
GTTTTACCTGGGGAATTCATCAAATCCAAGAATTCATTCCTGGTTCCTACAACGATAGAACCATCCTATTTTTACCGCCT
TGGCATATTGCAGAAAGACTTTTAGAAACAACCCTCATTGCCTGGGGAGCTTCAATGGCTTGTTCTTCTATCCCGACGAT
TCCAGCGGATATGCAAAAAGTAAAACCTACGGTTTTAGTTTCTGTTCCTAGACTTTGGGAGGGTCTTTATAAAAGAATTT
ATGATACTGTCAGAAAATCCTCTCCTTTCAAACAAAAACTTTTTCACTTTGCGGTTAAAATGGCCGAGATTACCACAAGC
CTTCAAGATACAATTCGAGATTCTTATGCTACCACGGAAACAGAAAACCCAAATCAGAAATTGTTAGATCGTTTTATTGC
GAGTGTATTTTTACTTTCCTTGGTTCCGATCAAAATCCTTTCCAATAAAATTTTAGAAAGAGTAAGAAATCTATTCGGTG
GTAAAATTAGATTCGCGTTATGTGGTGCTGGGGCTATGCCTTCACATATTCAATTTTTTTTTCGAAGTGCCGGAATCCAT
ATCATCGAAACCTACGGAATGACTGAAACGACCGGAATCGGAGCTATTGGTGAATTTCCAATTCCAAAAAATGGAGCCAT
CGGTGCTCCGTTACCCGGAACCGCAATCAAACTTGTAGGAGAAAACGGTAAAGTTGTTACAACTCCAGGCGAAAAAGGAG
TCGCTTGGCACAAAGGTCCTCACGTAACAATGGGCTATTATAAAGAACCTGAAAAAACTTCCAAGGCATTACAAGACGGA
TGGTTGGATTCAGGAGATATTCTTACTTGGACTCATACTGGAGAATTAAAATTTGCAGGAAGAGCAAAGGATACGATCGT
TCTTTCCGGTGGAGAAAACTTAGAACCTGCTCCGATCGAGGCAAAACTTACAGAATCAGAATTTATCAATCAAGTGATCG
TAGTTGGTCAGGATCAAAAAAACCTGGGAGTTTTAATTGTTCCTTTTTTTGATCGTGTTCAGGAAGAATTTCAAAACCAA
GCAGTAAAAATTCCAAAAGATCCGACTGAGTGGAGTTCTTCCAAAGAAGTCACCACGTTTTTTAAAAACATAGTTAAAGA
TAAAATTTCCACAAAAGCGGGTTTTAAATCCTTTGAAAAGATCGCTCATGTTCATATACTTTCTAAGGAGTTTGAAAAGG
GAAAAGAAATGACAGAGACAATGAAACTCAAACGAAACGTTATTTTTGATTTATATCAAGATGTAATTCAATCTTTGTAC
GATCATGATGAAGATTAA

Upstream 100 bases:

>100_bases
CACTGGATAATCTAGTAAAAGGTGCCGCGGGTCAGGCTTTACAAAACATCAATTTAATGACTGGAGCCAAAGAAACCTTG
GGGTTACTTCCCTAATCTCT

Downstream 100 bases:

>100_bases
ACTTCCAAAAACCACTCTAATCTGTTCTGCGATCAAAGAAGAAGTAGATCAGATTTTAAAATTAGAAAAATTTACGGTTT
TTGTTTGTGGAATCGGAAAT

Product: long-chain-fatty-acid CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MEKTSLYHLIRDVASVYSDRPMYWIREESGDFRGISYKDWYENLKNLSTFLIDLGMHKGNTAGLICDNRYEWSLCSLSLV
TIGCVDVPRGCDATIEDLKYILEHSEAKILFLENEKVLKKLLENKSSLAKVKTILLIDPPTKWKDLENSRALLSGIQFLF
LEDALLEGEKSRIKKGDKTYDQRGESLGGKDLATIIYTSGTTGAPKGVMLNHRSFTWGIHQIQEFIPGSYNDRTILFLPP
WHIAERLLETTLIAWGASMACSSIPTIPADMQKVKPTVLVSVPRLWEGLYKRIYDTVRKSSPFKQKLFHFAVKMAEITTS
LQDTIRDSYATTETENPNQKLLDRFIASVFLLSLVPIKILSNKILERVRNLFGGKIRFALCGAGAMPSHIQFFFRSAGIH
IIETYGMTETTGIGAIGEFPIPKNGAIGAPLPGTAIKLVGENGKVVTTPGEKGVAWHKGPHVTMGYYKEPEKTSKALQDG
WLDSGDILTWTHTGELKFAGRAKDTIVLSGGENLEPAPIEAKLTESEFINQVIVVGQDQKNLGVLIVPFFDRVQEEFQNQ
AVKIPKDPTEWSSSKEVTTFFKNIVKDKISTKAGFKSFEKIAHVHILSKEFEKGKEMTETMKLKRNVIFDLYQDVIQSLY
DHDED

Sequences:

>Translated_645_residues
MEKTSLYHLIRDVASVYSDRPMYWIREESGDFRGISYKDWYENLKNLSTFLIDLGMHKGNTAGLICDNRYEWSLCSLSLV
TIGCVDVPRGCDATIEDLKYILEHSEAKILFLENEKVLKKLLENKSSLAKVKTILLIDPPTKWKDLENSRALLSGIQFLF
LEDALLEGEKSRIKKGDKTYDQRGESLGGKDLATIIYTSGTTGAPKGVMLNHRSFTWGIHQIQEFIPGSYNDRTILFLPP
WHIAERLLETTLIAWGASMACSSIPTIPADMQKVKPTVLVSVPRLWEGLYKRIYDTVRKSSPFKQKLFHFAVKMAEITTS
LQDTIRDSYATTETENPNQKLLDRFIASVFLLSLVPIKILSNKILERVRNLFGGKIRFALCGAGAMPSHIQFFFRSAGIH
IIETYGMTETTGIGAIGEFPIPKNGAIGAPLPGTAIKLVGENGKVVTTPGEKGVAWHKGPHVTMGYYKEPEKTSKALQDG
WLDSGDILTWTHTGELKFAGRAKDTIVLSGGENLEPAPIEAKLTESEFINQVIVVGQDQKNLGVLIVPFFDRVQEEFQNQ
AVKIPKDPTEWSSSKEVTTFFKNIVKDKISTKAGFKSFEKIAHVHILSKEFEKGKEMTETMKLKRNVIFDLYQDVIQSLY
DHDED
>Mature_645_residues
MEKTSLYHLIRDVASVYSDRPMYWIREESGDFRGISYKDWYENLKNLSTFLIDLGMHKGNTAGLICDNRYEWSLCSLSLV
TIGCVDVPRGCDATIEDLKYILEHSEAKILFLENEKVLKKLLENKSSLAKVKTILLIDPPTKWKDLENSRALLSGIQFLF
LEDALLEGEKSRIKKGDKTYDQRGESLGGKDLATIIYTSGTTGAPKGVMLNHRSFTWGIHQIQEFIPGSYNDRTILFLPP
WHIAERLLETTLIAWGASMACSSIPTIPADMQKVKPTVLVSVPRLWEGLYKRIYDTVRKSSPFKQKLFHFAVKMAEITTS
LQDTIRDSYATTETENPNQKLLDRFIASVFLLSLVPIKILSNKILERVRNLFGGKIRFALCGAGAMPSHIQFFFRSAGIH
IIETYGMTETTGIGAIGEFPIPKNGAIGAPLPGTAIKLVGENGKVVTTPGEKGVAWHKGPHVTMGYYKEPEKTSKALQDG
WLDSGDILTWTHTGELKFAGRAKDTIVLSGGENLEPAPIEAKLTESEFINQVIVVGQDQKNLGVLIVPFFDRVQEEFQNQ
AVKIPKDPTEWSSSKEVTTFFKNIVKDKISTKAGFKSFEKIAHVHILSKEFEKGKEMTETMKLKRNVIFDLYQDVIQSLY
DHDED

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794760, Length=684, Percent_Identity=27.3391812865497, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI42794758, Length=684, Percent_Identity=27.3391812865497, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI42794756, Length=684, Percent_Identity=27.3391812865497, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI40807491, Length=660, Percent_Identity=27.8787878787879, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI57165412, Length=666, Percent_Identity=26.1261261261261, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI57165410, Length=664, Percent_Identity=25.6024096385542, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI83745141, Length=634, Percent_Identity=25.5520504731861, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI27477105, Length=644, Percent_Identity=24.0683229813665, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI42794754, Length=639, Percent_Identity=25.3521126760563, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI42794752, Length=639, Percent_Identity=25.3521126760563, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4758332, Length=565, Percent_Identity=24.6017699115044, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI12669909, Length=565, Percent_Identity=24.6017699115044, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI156151445, Length=185, Percent_Identity=30.8108108108108, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI145693145, Length=267, Percent_Identity=26.9662921348315, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788107, Length=161, Percent_Identity=32.9192546583851, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788595, Length=250, Percent_Identity=24.8, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17510401, Length=658, Percent_Identity=28.8753799392097, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17556552, Length=637, Percent_Identity=27.7864992150706, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17564090, Length=587, Percent_Identity=26.2350936967632, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17541856, Length=623, Percent_Identity=26.4847512038523, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193204819, Length=566, Percent_Identity=27.5618374558304, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553312, Length=638, Percent_Identity=25.0783699059561, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25147511, Length=651, Percent_Identity=24.8847926267281, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17531443, Length=202, Percent_Identity=29.2079207920792, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558820, Length=202, Percent_Identity=31.1881188118812, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133901848, Length=227, Percent_Identity=29.9559471365639, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32563687, Length=203, Percent_Identity=28.0788177339901, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324893, Length=471, Percent_Identity=26.5392781316348, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322182, Length=544, Percent_Identity=23.7132352941176, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6323903, Length=471, Percent_Identity=26.5392781316348, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320852, Length=615, Percent_Identity=25.8536585365854, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24666501, Length=657, Percent_Identity=26.027397260274, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24666497, Length=657, Percent_Identity=26.027397260274, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281366413, Length=657, Percent_Identity=26.027397260274, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17933690, Length=673, Percent_Identity=23.6255572065379, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62471681, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI62471687, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24586634, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI22026970, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI62471689, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI62471679, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI62471683, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI62471685, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24586636, Length=534, Percent_Identity=27.1535580524345, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19921316, Length=685, Percent_Identity=23.0656934306569, Blast_Score=133, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 72543; Mature: 72543

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTSLYHLIRDVASVYSDRPMYWIREESGDFRGISYKDWYENLKNLSTFLIDLGMHKGN
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TAGLICDNRYEWSLCSLSLVTIGCVDVPRGCDATIEDLKYILEHSEAKILFLENEKVLKK
CEEEEECCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHH
LLENKSSLAKVKTILLIDPPTKWKDLENSRALLSGIQFLFLEDALLEGEKSRIKKGDKTY
HHHCHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH
DQRGESLGGKDLATIIYTSGTTGAPKGVMLNHRSFTWGIHQIQEFIPGSYNDRTILFLPP
HHCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECC
WHIAERLLETTLIAWGASMACSSIPTIPADMQKVKPTVLVSVPRLWEGLYKRIYDTVRKS
HHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHCC
SPFKQKLFHFAVKMAEITTSLQDTIRDSYATTETENPNQKLLDRFIASVFLLSLVPIKIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SNKILERVRNLFGGKIRFALCGAGAMPSHIQFFFRSAGIHIIETYGMTETTGIGAIGEFP
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
IPKNGAIGAPLPGTAIKLVGENGKVVTTPGEKGVAWHKGPHVTMGYYKEPEKTSKALQDG
CCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHC
WLDSGDILTWTHTGELKFAGRAKDTIVLSGGENLEPAPIEAKLTESEFINQVIVVGQDQK
CCCCCCEEEEEECCCEEECCCCCCEEEEECCCCCCCCCCCEEECHHHHHCEEEEEECCCC
NLGVLIVPFFDRVQEEFQNQAVKIPKDPTEWSSSKEVTTFFKNIVKDKISTKAGFKSFEK
CCCEEEECHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHVHILSKEFEKGKEMTETMKLKRNVIFDLYQDVIQSLYDHDED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKTSLYHLIRDVASVYSDRPMYWIREESGDFRGISYKDWYENLKNLSTFLIDLGMHKGN
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TAGLICDNRYEWSLCSLSLVTIGCVDVPRGCDATIEDLKYILEHSEAKILFLENEKVLKK
CEEEEECCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHH
LLENKSSLAKVKTILLIDPPTKWKDLENSRALLSGIQFLFLEDALLEGEKSRIKKGDKTY
HHHCHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCH
DQRGESLGGKDLATIIYTSGTTGAPKGVMLNHRSFTWGIHQIQEFIPGSYNDRTILFLPP
HHCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECC
WHIAERLLETTLIAWGASMACSSIPTIPADMQKVKPTVLVSVPRLWEGLYKRIYDTVRKS
HHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHCC
SPFKQKLFHFAVKMAEITTSLQDTIRDSYATTETENPNQKLLDRFIASVFLLSLVPIKIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SNKILERVRNLFGGKIRFALCGAGAMPSHIQFFFRSAGIHIIETYGMTETTGIGAIGEFP
HHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCC
IPKNGAIGAPLPGTAIKLVGENGKVVTTPGEKGVAWHKGPHVTMGYYKEPEKTSKALQDG
CCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHC
WLDSGDILTWTHTGELKFAGRAKDTIVLSGGENLEPAPIEAKLTESEFINQVIVVGQDQK
CCCCCCEEEEEECCCEEECCCCCCEEEEECCCCCCCCCCCEEECHHHHHCEEEEEECCCC
NLGVLIVPFFDRVQEEFQNQAVKIPKDPTEWSSSKEVTTFFKNIVKDKISTKAGFKSFEK
CCCEEEECHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAHVHILSKEFEKGKEMTETMKLKRNVIFDLYQDVIQSLYDHDED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]