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The map label for this gene is yegE [H]

Identifier: 45657014

GI number: 45657014

Start: 1394159

End: 1395106

Strand: Reverse

Name: yegE [H]

Synonym: LIC11130

Alternate gene names: 45657014

Gene position: 1395106-1394159 (Counterclockwise)

Preceding gene: 45657015

Following gene: 45657013

Centisome position: 32.62

GC content: 35.44

Gene sequence:

>948_bases
TTGGAATATAAAAACGAATACAATCTTGAAAAATTCTACAACTATTCTTTGGATTTATTCTCCATTCAAAGAATGGACGG
GACCGTCATTTCCGTAAATCCATCCTTTGAAAGAATTTTAGGTTGGAAAGAAGAAGAACTACTAGGTAAAAACCCTTTTC
ATCTTTTACATCCCGAGGATCAAGAAACGATTGTACAAGAATTCCAAAAATTAGACGGAGGGATTCCTAGATACTCCATT
AAAAATCGTTGTAGATGTGCAGACGGAACGTACAAACATTTTGCTTGGACTGGTTTTCCAGATATAGAATCTGGTTTGGT
TTATATAACAGGCAGAGATATTACCGAAACAATCGAATCCAACCGTAAGATCAGTCAATTGGCAACTGAACTTAAAGACG
CCAATGATAAACTGTTCGAACAAGCATCTACCGATTCGTTGACAAAACTAAAAAATAGAAGAGCCTTCAATGAAGCATTA
AATCATTTAGTTCATTTCTCTCAAAAACAAAAAAGTCCTCTTTCACTGTTGATGATCGATGCAGACCATTTTAAAGACTA
CAACGATACGTTTGGGCATCTTGAAGGAGATAAAATTTTAATCATTTTAGCGGATCTTTTGACAAAAGCACTTCGAAAAG
GTGACGTACTCGCTAGATACGGAGGAGAAGAATTTATCGTAGCTCTTCCGCTGACCTCCGAAGACGAGACAATTGACATT
TCGGAAAGACTCCTTCAAACCGTGAGAGAATTTAATTGGGAAAAAAGAATTATCACAGTCAGTGTTGGTGCAGCTACATA
CGACTTTAATTCAAATTCCAAGAACATAAATTTAGAATATTCTATAAATCTAATTGAGCAAGCAGATAAGGCTCTCTATT
GCTCCAAAGTGAACGGCAGAAATAGAATCACACATTTTTCAAAAAAATACTCCTTACAACAAAATTAA

Upstream 100 bases:

>100_bases
ATTAGGCCCATTTTGAAGAGCTCCATTTTCAGGTTCAAAATGGCAAAACTGATTCGTTGTAAAAGAAACTTTAATTTTAT
AAATAACCGGAGAAAATAAT

Downstream 100 bases:

>100_bases
AATACGGAACTAGAAAATTATGAATTTTGAAAACGAATACGACCTCGAAAAACTTGTAAATAACTCTTTGGATTTACTTA
CAATCGTAGACCTAAGCGGA

Product: GGDEF family protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEYKNEYNLEKFYNYSLDLFSIQRMDGTVISVNPSFERILGWKEEELLGKNPFHLLHPEDQETIVQEFQKLDGGIPRYSI
KNRCRCADGTYKHFAWTGFPDIESGLVYITGRDITETIESNRKISQLATELKDANDKLFEQASTDSLTKLKNRRAFNEAL
NHLVHFSQKQKSPLSLLMIDADHFKDYNDTFGHLEGDKILIILADLLTKALRKGDVLARYGGEEFIVALPLTSEDETIDI
SERLLQTVREFNWEKRIITVSVGAATYDFNSNSKNINLEYSINLIEQADKALYCSKVNGRNRITHFSKKYSLQQN

Sequences:

>Translated_315_residues
MEYKNEYNLEKFYNYSLDLFSIQRMDGTVISVNPSFERILGWKEEELLGKNPFHLLHPEDQETIVQEFQKLDGGIPRYSI
KNRCRCADGTYKHFAWTGFPDIESGLVYITGRDITETIESNRKISQLATELKDANDKLFEQASTDSLTKLKNRRAFNEAL
NHLVHFSQKQKSPLSLLMIDADHFKDYNDTFGHLEGDKILIILADLLTKALRKGDVLARYGGEEFIVALPLTSEDETIDI
SERLLQTVREFNWEKRIITVSVGAATYDFNSNSKNINLEYSINLIEQADKALYCSKVNGRNRITHFSKKYSLQQN
>Mature_315_residues
MEYKNEYNLEKFYNYSLDLFSIQRMDGTVISVNPSFERILGWKEEELLGKNPFHLLHPEDQETIVQEFQKLDGGIPRYSI
KNRCRCADGTYKHFAWTGFPDIESGLVYITGRDITETIESNRKISQLATELKDANDKLFEQASTDSLTKLKNRRAFNEAL
NHLVHFSQKQKSPLSLLMIDADHFKDYNDTFGHLEGDKILIILADLLTKALRKGDVLARYGGEEFIVALPLTSEDETIDI
SERLLQTVREFNWEKRIITVSVGAATYDFNSNSKNINLEYSINLIEQADKALYCSKVNGRNRITHFSKKYSLQQN

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=296, Percent_Identity=29.7297297297297, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI145693134, Length=190, Percent_Identity=36.3157894736842, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081881, Length=284, Percent_Identity=29.9295774647887, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082007, Length=208, Percent_Identity=32.6923076923077, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787262, Length=200, Percent_Identity=33, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=34.1317365269461, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=33.1288343558282, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787541, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081977, Length=126, Percent_Identity=39.6825396825397, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788956, Length=268, Percent_Identity=28.7313432835821, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787056, Length=169, Percent_Identity=31.3609467455621, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081974, Length=114, Percent_Identity=29.8245614035088, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36368; Mature: 36368

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKNEYNLEKFYNYSLDLFSIQRMDGTVISVNPSFERILGWKEEELLGKNPFHLLHPED
CCCCCCCCHHHHHCCCCEEEEEEECCCEEEEECCCHHHHHCCCHHHHCCCCCEEEECCCC
QETIVQEFQKLDGGIPRYSIKNRCRCADGTYKHFAWTGFPDIESGLVYITGRDITETIES
HHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEECCCCCCCCCEEEEECCCHHHHHHC
NRKISQLATELKDANDKLFEQASTDSLTKLKNRRAFNEALNHLVHFSQKQKSPLSLLMID
CCHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
ADHFKDYNDTFGHLEGDKILIILADLLTKALRKGDVLARYGGEEFIVALPLTSEDETIDI
HHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCEECH
SERLLQTVREFNWEKRIITVSVGAATYDFNSNSKNINLEYSINLIEQADKALYCSKVNGR
HHHHHHHHHHCCCCCEEEEEEECEEEEECCCCCCEEEEEEEEEHHHHCCHHEEEECCCCC
NRITHFSKKYSLQQN
CHHHHHHHHCCCCCC
>Mature Secondary Structure
MEYKNEYNLEKFYNYSLDLFSIQRMDGTVISVNPSFERILGWKEEELLGKNPFHLLHPED
CCCCCCCCHHHHHCCCCEEEEEEECCCEEEEECCCHHHHHCCCHHHHCCCCCEEEECCCC
QETIVQEFQKLDGGIPRYSIKNRCRCADGTYKHFAWTGFPDIESGLVYITGRDITETIES
HHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCEEECCCCCCCCCEEEEECCCHHHHHHC
NRKISQLATELKDANDKLFEQASTDSLTKLKNRRAFNEALNHLVHFSQKQKSPLSLLMID
CCHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
ADHFKDYNDTFGHLEGDKILIILADLLTKALRKGDVLARYGGEEFIVALPLTSEDETIDI
HHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCEECH
SERLLQTVREFNWEKRIITVSVGAATYDFNSNSKNINLEYSINLIEQADKALYCSKVNGR
HHHHHHHHHHCCCCCEEEEEEECEEEEECCCCCCEEEEEEEEEHHHHCCHHEEEECCCCC
NRITHFSKKYSLQQN
CHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]