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The map label for this gene is yegE [H]

Identifier: 45657013

GI number: 45657013

Start: 1393186

End: 1394139

Strand: Reverse

Name: yegE [H]

Synonym: LIC11129

Alternate gene names: 45657013

Gene position: 1394139-1393186 (Counterclockwise)

Preceding gene: 45657014

Following gene: 45657012

Centisome position: 32.59

GC content: 36.37

Gene sequence:

>954_bases
ATGAATTTTGAAAACGAATACGACCTCGAAAAACTTGTAAATAACTCTTTGGATTTACTTACAATCGTAGACCTAAGCGG
AAACGTTCTACTCGTAAATCCTGCTTTTGAACGGACCTTAGGTTGGAAAAAAGAAGACCTAGTCGGTAAGGATCCGTTTC
ATCTTCTTCATCCAGAAGATAAGGAAAGTACTTATAAGGAATTTGAAAAATTAAATCAAGGTCTACTTACTTTATCCTTT
CAAAATCGATATATTTGTGCAGACGGACAGTATAGATATTTTTCTTGGACCGCTTCCCCTGACTTGGTGTCTGGTTTAGT
CTACGTTACAGGAAGAGACATCACCGATGTGATCGAATCCAACCGTAAGATCAGTCAATTGGCAGTAAAACTCAAAGAAA
CAAATGATAGATTATTTGAACAAGCATCTACCGATCCATTGACAAAACTAAAAAACAGAAGAATGTTCAACGAGGAATTG
AACAACCTCATACATGCTTGTGATAAAGAATCACATCCTCTTTCTTTGTTGATGATTGACGCAGATCACTTTAAAGATTA
TAACGACAAATTCGGACATATTGCCGGAGACAAGGTTCTGGTGGAATTAGCATCCATTTTGACAAAAACGTTTCGAAAAA
AAGACGTTTTAGCTCGTTATGGAGGTGAAGAATTTATCGCAGCTCTTCCCAATACTTCTGAACCAGAAGCGAATCAAATT
GCAGAAAGACTCGTCCAAACCGTGAGAGAATTTAGTTGGGAAAAAAGATCTGTTACAATCAGTGTAGGGATTACTACATA
TAACTTTAATCCGACTTCGAAAAGTATAAATTCAGAATACCTTCTAAATCTAATTGAACAAGCAGACAAGGCTCTTTATT
GTTCCAAAGTAAGCGGTAGGGATAGAATCACACATTTTTCATGGGTCCAAAATAAAAAGAGCGGATCTATTTAA

Upstream 100 bases:

>100_bases
AAGGCTCTCTATTGCTCCAAAGTGAACGGCAGAAATAGAATCACACATTTTTCAAAAAAATACTCCTTACAACAAAATTA
AAATACGGAACTAGAAAATT

Downstream 100 bases:

>100_bases
AATCAATATTATGGAATTGTAAAATGACGAATTTTGAAAAAGAATACGATCTTGAAAAACTTGTAAACAACTCTTTGGAT
TTACTATCGATTCAGAGATT

Product: GGDEF family protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPEDKESTYKEFEKLNQGLLTLSF
QNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIESNRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEEL
NNLIHACDKESHPLSLLMIDADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGRDRITHFSWVQNKKSGSI

Sequences:

>Translated_317_residues
MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPEDKESTYKEFEKLNQGLLTLSF
QNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIESNRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEEL
NNLIHACDKESHPLSLLMIDADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGRDRITHFSWVQNKKSGSI
>Mature_317_residues
MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPEDKESTYKEFEKLNQGLLTLSF
QNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIESNRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEEL
NNLIHACDKESHPLSLLMIDADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGRDRITHFSWVQNKKSGSI

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=316, Percent_Identity=29.4303797468354, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=36.969696969697, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI145693134, Length=190, Percent_Identity=34.7368421052632, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=35, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081881, Length=242, Percent_Identity=32.2314049586777, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=34.3195266272189, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787541, Length=324, Percent_Identity=23.7654320987654, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=32.7160493827161, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=31.0975609756098, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87081977, Length=123, Percent_Identity=34.9593495934959, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788956, Length=119, Percent_Identity=37.8151260504202, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788085, Length=225, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787056, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36299; Mature: 36299

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPED
CCCCCCCCHHHHHCCCCCEEEEEECCCCEEEECCHHHHHCCCCHHHCCCCCCCCCCCCCC
KESTYKEFEKLNQGLLTLSFQNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIES
CHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEEEECCCHHHHCCEEEEECCCHHHHHHC
NRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEELNNLIHACDKESHPLSLLMID
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
ADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCHHHH
AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGR
HHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCCCCC
DRITHFSWVQNKKSGSI
CCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPED
CCCCCCCCHHHHHCCCCCEEEEEECCCCEEEECCHHHHHCCCCHHHCCCCCCCCCCCCCC
KESTYKEFEKLNQGLLTLSFQNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIES
CHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEEEECCCHHHHCCEEEEECCCHHHHHHC
NRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEELNNLIHACDKESHPLSLLMID
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
ADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCHHHH
AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGR
HHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEEECCCCCC
DRITHFSWVQNKKSGSI
CCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]