| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is mlr
Identifier: 45656569
GI number: 45656569
Start: 816379
End: 817143
Strand: Direct
Name: mlr
Synonym: LIC10671
Alternate gene names: 45656569
Gene position: 816379-817143 (Clockwise)
Preceding gene: 45656567
Following gene: 45656573
Centisome position: 19.09
GC content: 38.43
Gene sequence:
>765_bases ATGCCTAGTTCCGATAAAGCCATAGAAATTCAAAAATTAAATCTCCGATTGGGTCAAAGGATAATCTTAGATTCGATTTC TTTCGAAGTGAATTCCGGAACGATACTTGGAATTTTAGGTCGTTCCGGTTCAGGTAAAACTTCTCTTTTCCGAGCGATTT TAGGAGTTCCTACAACCACGAATCTGGAACAAAGCGGATCGATTTATTTTTTTGGAAAGGCCCGAAAAGAAATTCCGATC CATCATTTACAACCAGTCTTTCAAGATCCTGTCGGAAGTTTCAACCCTGCCTGGTCTTTGGAAAAAGCTTTGAAAGAACC ACTCCGAATTTTAGGGGGAGAAATTGCAAATAGGGGAGAGGCTTTTTTCCCAGATTTACTAGAGTCTTTTCGGTTGGCAA ATAAAGATCTCAATCGAAATGTACTTTCTTTTTCCGGAGGTGAACTACAAAGGGCAGCGATTCTTCGCGCTCTTCTTACT GAACCTAAGATTCTTTTTTTGGACGAGGCATTAGGTGCTTTGGATCCAATCCTTTTGAACGATGTATTACAATTTTTAAA GAGGATTTCCAGGGAAAGGAAAATTACGATTTTATTAATTACTCATAGTTTGAGGACGGCTCAAAAATTCTGCAATCAAA TTGGAATATTAGAAAAAGGTAAATTATTAGATTTTGGAACAACGGAAGAAGTGTTTACGAATTATAAAAGTTCTTTTACG GGGGAACTCATTCGTGCGATCGATTTGAGTTCCCTCCGCGCTTGA
Upstream 100 bases:
>100_bases CATCGAACTCACGTCGGAGTTAATATCTTTTACAACGTGAGAGCTCCCACATTTTTAAGAATTCTTGTTTTAAAAAAAGG ATAATTCTACTTTGTAAGAA
Downstream 100 bases:
>100_bases TCAGATGTCGATCTGATAGAGATTTTTTCTGTCTTTTTTGTCTTTGTAAAGTGCGATCATAATATCGATTCGGTAGATCG AAGATCTGAGGCTAGACTCT
Product: ABC transporter ATP-binding protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPI HHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLT EPKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT GELIRAIDLSSLRA
Sequences:
>Translated_254_residues MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPI HHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLT EPKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT GELIRAIDLSSLRA >Mature_253_residues PSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPIH HLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTE PKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFTG ELIRAIDLSSLRA
Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]
COG id: COG1123
COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI171184400, Length=228, Percent_Identity=31.140350877193, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI27436953, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI148612844, Length=225, Percent_Identity=31.5555555555556, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI11967969, Length=227, Percent_Identity=29.9559471365639, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI255708477, Length=228, Percent_Identity=32.0175438596491, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI27262624, Length=228, Percent_Identity=22.8070175438596, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI27262626, Length=228, Percent_Identity=22.8070175438596, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI42741659, Length=224, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789891, Length=215, Percent_Identity=31.6279069767442, Blast_Score=124, Evalue=4e-30, Organism=Escherichia coli, GI1788506, Length=232, Percent_Identity=31.4655172413793, Blast_Score=120, Evalue=9e-29, Organism=Escherichia coli, GI1787500, Length=244, Percent_Identity=29.9180327868852, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI145693107, Length=235, Percent_Identity=29.3617021276596, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1789962, Length=234, Percent_Identity=28.6324786324786, Blast_Score=107, Evalue=6e-25, Organism=Escherichia coli, GI48994883, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1787758, Length=220, Percent_Identity=28.1818181818182, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1786398, Length=242, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787089, Length=245, Percent_Identity=31.0204081632653, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1789963, Length=255, Percent_Identity=26.2745098039216, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788225, Length=253, Percent_Identity=28.0632411067194, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1788761, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1787759, Length=258, Percent_Identity=25.5813953488372, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87081791, Length=253, Percent_Identity=27.6679841897233, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI48994997, Length=227, Percent_Identity=27.3127753303965, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787712, Length=240, Percent_Identity=28.3333333333333, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787548, Length=241, Percent_Identity=26.5560165975104, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=28.0172413793103, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787029, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI87081709, Length=245, Percent_Identity=27.3469387755102, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789890, Length=243, Percent_Identity=25.9259259259259, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI48994943, Length=245, Percent_Identity=28.1632653061224, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1788644, Length=254, Percent_Identity=29.5275590551181, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789593, Length=236, Percent_Identity=29.2372881355932, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786698, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789032, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1787547, Length=224, Percent_Identity=24.5535714285714, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI87081782, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=30.5164319248826, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1790467, Length=242, Percent_Identity=25.6198347107438, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=32.2429906542056, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788450, Length=235, Percent_Identity=24.6808510638298, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1787112, Length=224, Percent_Identity=31.6964285714286, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1789672, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1786319, Length=235, Percent_Identity=28.5106382978723, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786345, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI87082268, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87082267, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786703, Length=236, Percent_Identity=29.2372881355932, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788053, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788165, Length=230, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786803, Length=237, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786872, Length=110, Percent_Identity=30.9090909090909, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1790739, Length=242, Percent_Identity=23.1404958677686, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1790162, Length=97, Percent_Identity=29.8969072164948, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI2367384, Length=207, Percent_Identity=28.0193236714976, Blast_Score=61, Evalue=8e-11, Organism=Escherichia coli, GI1786981, Length=216, Percent_Identity=33.7962962962963, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17565938, Length=236, Percent_Identity=30.0847457627119, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI25146777, Length=229, Percent_Identity=31.8777292576419, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17543740, Length=222, Percent_Identity=29.2792792792793, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI193208177, Length=217, Percent_Identity=30.4147465437788, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17533971, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551702, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551700, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193211017, Length=247, Percent_Identity=29.1497975708502, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71996809, Length=245, Percent_Identity=29.3877551020408, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193211015, Length=245, Percent_Identity=29.3877551020408, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71983523, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71983516, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI71983510, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI212646699, Length=223, Percent_Identity=30.9417040358744, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17569081, Length=245, Percent_Identity=28.9795918367347, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193202349, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71992290, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71984940, Length=219, Percent_Identity=29.6803652968037, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI115533608, Length=213, Percent_Identity=24.8826291079812, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI115532730, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17567269, Length=217, Percent_Identity=29.4930875576037, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6324985, Length=226, Percent_Identity=26.9911504424779, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322640, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI28573571, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28573573, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI85725262, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI23397593, Length=229, Percent_Identity=30.5676855895196, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI85726357, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24643674, Length=260, Percent_Identity=23.4615384615385, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574533, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24648314, Length=212, Percent_Identity=25.9433962264151, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR015858 - InterPro: IPR003593 - InterPro: IPR014137 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: =3.6.3.24 [H]
Molecular weight: Translated: 28192; Mature: 28061
Theoretical pI: Translated: 10.01; Mature: 10.01
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.4 %Met (Translated Protein) 0.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.0 %Met (Mature Protein) 0.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTT CCCCCCEEEEEEHHHHHCHHHHHHHHEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCC NLEQSGSIYFFGKARKEIPIHHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGE CCCCCCCEEEEECCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCC AFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTEPKILFLDEALGALDPILLN CHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH DVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT HHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH GELIRAIDLSSLRA HHHHHHHHHHHHCC >Mature Secondary Structure PSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTT CCCCCEEEEEEHHHHHCHHHHHHHHEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCC NLEQSGSIYFFGKARKEIPIHHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGE CCCCCCCEEEEECCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCC AFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTEPKILFLDEALGALDPILLN CHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH DVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT HHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH GELIRAIDLSSLRA HHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]