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The map label for this gene is nuoG

Identifier: 45656051

GI number: 45656051

Start: 170447

End: 171895

Strand: Direct

Name: nuoG

Synonym: LIC10141

Alternate gene names: 45656051

Gene position: 170447-171895 (Clockwise)

Preceding gene: 45656050

Following gene: 45656052

Centisome position: 3.99

GC content: 38.37

Gene sequence:

>1449_bases
ATGGTAAAAATTAAGATCGACGGAATCGAATATGAGGTGGATGAAAAAAAGAACCTCATATCAGCGGCAAAAGATGTCGG
AGTCGATATTCCTTTCTTCTGTTATCACCCCAAACTTTCCATTGTGGGAATGTGTAGAATGTGCCTTATCGAAATTGAAG
GAGTTCCTAGACTTCAAGCAGCTTGCAATACGAAGGTAACGGAAGGTCTTTCCATTTTCACCAAAAACGATCGAATTAAA
GAAGCAAGAGAAGGAACGATGGAGTTTCTTCTTGCGAATCACCCCTTAGATTGCCCCGTTTGCGACAAAGCTGGCGAATG
CCAGCTTCAGGACAATGCTTTCAAAGAAGGAAAGGGTAACTCCAGATTTACATTAGAAAAGCGGAATGTTCCTCAAGAAG
AAGTCGGTTCTAATCTAATCATTAATCATAACCGTTGTATTGTCTGTTATCGTTGTGTTCGATTTGAAGAAGAAATCGTA
GGAGAATCCAATTTAGGACTTTTTGAAAGAGGTTATCACTCTATCATAGGACTTGCAAAGAACGAACCAATTCAGCATAA
CTTTCAAGGAGCTCTTGCGGATCTTTGTCCTACGGGAGCACTTCTCAATAATAAAACCTTATTCAAATCTAGAGTATGGT
GGTATAAAAATGGGGAATCGATCTGCCATGGATGTAGTACTGGTTGCAATGTTACGACTAACGTAAGAGATAACAAAATG
TATCGATATATGCCTCGAATCGACGAAGAAAAGGACATGTATTTTCTTTGTGACCATGGGCGTTTTGACATCGATTGGTT
GAACGAAAATCGGTTATTCGCGTATTATCAAAATGGAAACGTATCGGAAAGTACCGTAGTGCTGCCTGCCATTGCGGAAA
GAGTTCGTCAATCAAAACGGATTGCGATTTTAGGTGGTGCAAAAGAATCGAACGAAAATTTAAAAACCATTCTTCAAAGT
GTGGAATCTTTTGAAAAATCGGTTATCGTAGAAGCAAGGGTAGAAGAAATTCAATACAAGGCGCCCGAGCAAAAAGATTT
TTTGATGACTACTGATTTTAGACCAAATACAAGAGGAGCGGTAGATTCCGGATTTATATCTTCGCAAGAAATCAATGCGA
TTTGTAAATCGATCGAGTTAGGAGAGATTGATCTGGTTTTTGTGATTCATGAGAATATTAAGAAATTTTTACATTCTATT
CCTTCGAACGTTACTCTTGTTTTATTAAATACAAATTTAACTCAAGAAATATCTGAAGCAACTTACGGAATTCCGATTCA
AACGTTTGCAGAACAAGCCGGTTCTTTTACAAATAAAAATGGATTGAATCAGTCTTTTCAAAAGGTAATGGAGCCGCCTA
AAGGTCTATTAAATTCTGGTTCTGTTTTCCGGAGAATAGCAGAATTGGTCAAAACTTCTCCCAAGGAGGCTGAGGTTGGG
AACCGTTAA

Upstream 100 bases:

>100_bases
AGATACACGATCCCGTTTTAGAAACGGGTTGCCAGAATGAGAATGGTACGTTTCTATAGAACTGTTCCCGAAATTCGGGA
AGAATCAAAAGGATGATTCC

Downstream 100 bases:

>100_bases
CGTAGTAAGAGTAGCAAGTCGTCATAAACTTTCTTGGTATGAAAAGTTTTATTTTTATTCTATTGGAAAAGGACTTTGGA
TCACTCTCAAACATTTTATT

Product: NADH dehydrogenase subunit I G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MVKIKIDGIEYEVDEKKNLISAAKDVGVDIPFFCYHPKLSIVGMCRMCLIEIEGVPRLQAACNTKVTEGLSIFTKNDRIK
EAREGTMEFLLANHPLDCPVCDKAGECQLQDNAFKEGKGNSRFTLEKRNVPQEEVGSNLIINHNRCIVCYRCVRFEEEIV
GESNLGLFERGYHSIIGLAKNEPIQHNFQGALADLCPTGALLNNKTLFKSRVWWYKNGESICHGCSTGCNVTTNVRDNKM
YRYMPRIDEEKDMYFLCDHGRFDIDWLNENRLFAYYQNGNVSESTVVLPAIAERVRQSKRIAILGGAKESNENLKTILQS
VESFEKSVIVEARVEEIQYKAPEQKDFLMTTDFRPNTRGAVDSGFISSQEINAICKSIELGEIDLVFVIHENIKKFLHSI
PSNVTLVLLNTNLTQEISEATYGIPIQTFAEQAGSFTNKNGLNQSFQKVMEPPKGLLNSGSVFRRIAELVKTSPKEAEVG
NR

Sequences:

>Translated_482_residues
MVKIKIDGIEYEVDEKKNLISAAKDVGVDIPFFCYHPKLSIVGMCRMCLIEIEGVPRLQAACNTKVTEGLSIFTKNDRIK
EAREGTMEFLLANHPLDCPVCDKAGECQLQDNAFKEGKGNSRFTLEKRNVPQEEVGSNLIINHNRCIVCYRCVRFEEEIV
GESNLGLFERGYHSIIGLAKNEPIQHNFQGALADLCPTGALLNNKTLFKSRVWWYKNGESICHGCSTGCNVTTNVRDNKM
YRYMPRIDEEKDMYFLCDHGRFDIDWLNENRLFAYYQNGNVSESTVVLPAIAERVRQSKRIAILGGAKESNENLKTILQS
VESFEKSVIVEARVEEIQYKAPEQKDFLMTTDFRPNTRGAVDSGFISSQEINAICKSIELGEIDLVFVIHENIKKFLHSI
PSNVTLVLLNTNLTQEISEATYGIPIQTFAEQAGSFTNKNGLNQSFQKVMEPPKGLLNSGSVFRRIAELVKTSPKEAEVG
NR
>Mature_482_residues
MVKIKIDGIEYEVDEKKNLISAAKDVGVDIPFFCYHPKLSIVGMCRMCLIEIEGVPRLQAACNTKVTEGLSIFTKNDRIK
EAREGTMEFLLANHPLDCPVCDKAGECQLQDNAFKEGKGNSRFTLEKRNVPQEEVGSNLIINHNRCIVCYRCVRFEEEIV
GESNLGLFERGYHSIIGLAKNEPIQHNFQGALADLCPTGALLNNKTLFKSRVWWYKNGESICHGCSTGCNVTTNVRDNKM
YRYMPRIDEEKDMYFLCDHGRFDIDWLNENRLFAYYQNGNVSESTVVLPAIAERVRQSKRIAILGGAKESNENLKTILQS
VESFEKSVIVEARVEEIQYKAPEQKDFLMTTDFRPNTRGAVDSGFISSQEINAICKSIELGEIDLVFVIHENIKKFLHSI
PSNVTLVLLNTNLTQEISEATYGIPIQTFAEQAGSFTNKNGLNQSFQKVMEPPKGLLNSGSVFRRIAELVKTSPKEAEVG
NR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=272, Percent_Identity=39.7058823529412, Blast_Score=224, Evalue=1e-58,
Organism=Escherichia coli, GI145693161, Length=325, Percent_Identity=33.5384615384615, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17565758, Length=317, Percent_Identity=35.9621451104101, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI32566231, Length=317, Percent_Identity=35.9621451104101, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=39.2857142857143, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24640559, Length=277, Percent_Identity=41.1552346570397, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24640557, Length=277, Percent_Identity=41.1552346570397, Blast_Score=222, Evalue=5e-58,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 54349; Mature: 54349

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIKIDGIEYEVDEKKNLISAAKDVGVDIPFFCYHPKLSIVGMCRMCLIEIEGVPRLQA
CEEEEECCEEEECCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHEECCCCHHHH
ACNTKVTEGLSIFTKNDRIKEAREGTMEFLLANHPLDCPVCDKAGECQLQDNAFKEGKGN
HHCCHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
SRFTLEKRNVPQEEVGSNLIINHNRCIVCYRCVRFEEEIVGESNLGLFERGYHSIIGLAK
CEEEEECCCCCHHHHCCCEEEECCCEEEEEEHHHHHHHHCCCCCCCHHHHCHHHHHCCCC
NEPIQHNFQGALADLCPTGALLNNKTLFKSRVWWYKNGESICHGCSTGCNVTTNVRDNKM
CCCCCCCHHHHHHHHCCCCCEECCCEEHHCEEEEEECCCHHHHCCCCCCEEEECCCCCCE
YRYMPRIDEEKDMYFLCDHGRFDIDWLNENRLFAYYQNGNVSESTVVLPAIAERVRQSKR
EEECCCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCC
IAILGGAKESNENLKTILQSVESFEKSVIVEARVEEIQYKAPEQKDFLMTTDFRPNTRGA
EEEEECCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
VDSGFISSQEINAICKSIELGEIDLVFVIHENIKKFLHSIPSNVTLVLLNTNLTQEISEA
CCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
TYGIPIQTFAEQAGSFTNKNGLNQSFQKVMEPPKGLLNSGSVFRRIAELVKTSPKEAEVG
HCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCCCC
NR
CC
>Mature Secondary Structure
MVKIKIDGIEYEVDEKKNLISAAKDVGVDIPFFCYHPKLSIVGMCRMCLIEIEGVPRLQA
CEEEEECCEEEECCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHEECCCCHHHH
ACNTKVTEGLSIFTKNDRIKEAREGTMEFLLANHPLDCPVCDKAGECQLQDNAFKEGKGN
HHCCHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
SRFTLEKRNVPQEEVGSNLIINHNRCIVCYRCVRFEEEIVGESNLGLFERGYHSIIGLAK
CEEEEECCCCCHHHHCCCEEEECCCEEEEEEHHHHHHHHCCCCCCCHHHHCHHHHHCCCC
NEPIQHNFQGALADLCPTGALLNNKTLFKSRVWWYKNGESICHGCSTGCNVTTNVRDNKM
CCCCCCCHHHHHHHHCCCCCEECCCEEHHCEEEEEECCCHHHHCCCCCCEEEECCCCCCE
YRYMPRIDEEKDMYFLCDHGRFDIDWLNENRLFAYYQNGNVSESTVVLPAIAERVRQSKR
EEECCCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCC
IAILGGAKESNENLKTILQSVESFEKSVIVEARVEEIQYKAPEQKDFLMTTDFRPNTRGA
EEEEECCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
VDSGFISSQEINAICKSIELGEIDLVFVIHENIKKFLHSIPSNVTLVLLNTNLTQEISEA
CCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
TYGIPIQTFAEQAGSFTNKNGLNQSFQKVMEPPKGLLNSGSVFRRIAELVKTSPKEAEVG
HCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCCCC
NR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]