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The map label for this gene is aroC

Identifier: 45656050

GI number: 45656050

Start: 168502

End: 169644

Strand: Direct

Name: aroC

Synonym: LIC10140

Alternate gene names: 45656050

Gene position: 168502-169644 (Clockwise)

Preceding gene: 45656049

Following gene: 45656051

Centisome position: 3.94

GC content: 40.94

Gene sequence:

>1143_bases
ATGCCTTCTAGCTGGGGAAAAATTTTTAAAGTTAGTACTTTCGGAGAATCTCATGGAACTTCTGTGGGAGTTGTGGTTGA
AGGAGTTCCCGCAGGAATTCCCATTCGTTTAGAAGAAATTCAAAAAGACTTAAACCGGAGAAGACCAGGACAAAGTAACC
TCACCACACCTAGAGATGAAACTGACACGGTTCGTGTAGTTTCTGGAGTATTTGAAGGAAAAACGATCGGATCTCCGATT
GCTTTGATCGTAGATAACCAAAATACGATTTCTAAAGACTACGAAAATTTAAGAACCACGTTTAGACCTTCTCACGCGGA
TTATACCTATCAAATGAAATACGGTTTTCGTGCGCATGTAGGCGGCGGACGTTCTTCCGTTCGAGAAACGATTGGTCGTG
TAGCCGCAGCCGCCATTGCGAGAATGATCCTCAAGGATGATCTTGGAATTGAAACTATTGCGTGGGTGGATTCGATCGGA
ACCGTTCAATCTAACATAGGTGATAAATATCCTAAGTCTAGGGAAGAAGTCGATCAAAATGAAGTTCGTTGTCCAGACGT
TGGTAGCGCTGACCAAATGCGTTCTTTGATTTTAAAAATGAAAGAAGCCGGAGATAGCGTAGGTGGAACGATCCAATGTG
TTTCTTATAATCTTCCTCCAGGTTTAGGAGATCCCGTATATGACAAGTTAGACGGAGATTTGGCAAAGGCGATACTTTCT
ATTCCTGCTTGTAAAGGATTCGAAGTGGGTTCCGGATTTTCTGGAACGTTATTAACCGGAAGTTCACATAACGATGAATT
TTACGTGGAAGAAGGAACTGGAAGAGTCAGGACTAGAACGAATCATTCTGGAGGACTCCAGGGTGGAATTTCCAATGGAG
AAGAATTAGTAATTCGTGCCGCTTTTAAACCAACCTCTACAATTTTTAAAAAACAGAATACTATAAATCTCAAAGGAGAA
GAAACCATTTTAGAAGCAAAAGGTCGTCATGATCCTTGTGTTCTCCCTAGAGCCGTTCCAATTATCGAGGCAGTTGTAAA
TTTAGTTCTCATAGACGCATATTTATATCAAAGGGCGATCAATCCTCAATGGTTCCAAAAGTGGGCTAGAATTCCAGATT
ATTACAAAGATTTAGAACTTTAA

Upstream 100 bases:

>100_bases
CAAAGTTTTAGAGGAACTGTTCCTCGTTCTGCGGCTTAAAACCAAAGGATTCTTTTAGAAACCGCTTTATTCCTGAGCTT
TCCCTTGTTTTTTTGGTAAT

Downstream 100 bases:

>100_bases
GAATCAGTCCCAAAAGGTGATTGTTCCAACTTTCGAGTGTAAGGTTCAAATCTTTTGGAGACCACTCTAAAATTAATTTT
ATTCGTCCCCGTTACGCTAC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPSSWGKIFKVSTFGESHGTSVGVVVEGVPAGIPIRLEEIQKDLNRRRPGQSNLTTPRDETDTVRVVSGVFEGKTIGSPI
ALIVDNQNTISKDYENLRTTFRPSHADYTYQMKYGFRAHVGGGRSSVRETIGRVAAAAIARMILKDDLGIETIAWVDSIG
TVQSNIGDKYPKSREEVDQNEVRCPDVGSADQMRSLILKMKEAGDSVGGTIQCVSYNLPPGLGDPVYDKLDGDLAKAILS
IPACKGFEVGSGFSGTLLTGSSHNDEFYVEEGTGRVRTRTNHSGGLQGGISNGEELVIRAAFKPTSTIFKKQNTINLKGE
ETILEAKGRHDPCVLPRAVPIIEAVVNLVLIDAYLYQRAINPQWFQKWARIPDYYKDLEL

Sequences:

>Translated_380_residues
MPSSWGKIFKVSTFGESHGTSVGVVVEGVPAGIPIRLEEIQKDLNRRRPGQSNLTTPRDETDTVRVVSGVFEGKTIGSPI
ALIVDNQNTISKDYENLRTTFRPSHADYTYQMKYGFRAHVGGGRSSVRETIGRVAAAAIARMILKDDLGIETIAWVDSIG
TVQSNIGDKYPKSREEVDQNEVRCPDVGSADQMRSLILKMKEAGDSVGGTIQCVSYNLPPGLGDPVYDKLDGDLAKAILS
IPACKGFEVGSGFSGTLLTGSSHNDEFYVEEGTGRVRTRTNHSGGLQGGISNGEELVIRAAFKPTSTIFKKQNTINLKGE
ETILEAKGRHDPCVLPRAVPIIEAVVNLVLIDAYLYQRAINPQWFQKWARIPDYYKDLEL
>Mature_379_residues
PSSWGKIFKVSTFGESHGTSVGVVVEGVPAGIPIRLEEIQKDLNRRRPGQSNLTTPRDETDTVRVVSGVFEGKTIGSPIA
LIVDNQNTISKDYENLRTTFRPSHADYTYQMKYGFRAHVGGGRSSVRETIGRVAAAAIARMILKDDLGIETIAWVDSIGT
VQSNIGDKYPKSREEVDQNEVRCPDVGSADQMRSLILKMKEAGDSVGGTIQCVSYNLPPGLGDPVYDKLDGDLAKAILSI
PACKGFEVGSGFSGTLLTGSSHNDEFYVEEGTGRVRTRTNHSGGLQGGISNGEELVIRAAFKPTSTIFKKQNTINLKGEE
TILEAKGRHDPCVLPRAVPIIEAVVNLVLIDAYLYQRAINPQWFQKWARIPDYYKDLEL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=369, Percent_Identity=46.070460704607, Blast_Score=311, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6321290, Length=366, Percent_Identity=51.3661202185792, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 41575; Mature: 41443

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSWGKIFKVSTFGESHGTSVGVVVEGVPAGIPIRLEEIQKDLNRRRPGQSNLTTPRDE
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCC
TDTVRVVSGVFEGKTIGSPIALIVDNQNTISKDYENLRTTFRPSHADYTYQMKYGFRAHV
CCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEC
GGGRSSVRETIGRVAAAAIARMILKDDLGIETIAWVDSIGTVQSNIGDKYPKSREEVDQN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
EVRCPDVGSADQMRSLILKMKEAGDSVGGTIQCVSYNLPPGLGDPVYDKLDGDLAKAILS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHH
IPACKGFEVGSGFSGTLLTGSSHNDEFYVEEGTGRVRTRTNHSGGLQGGISNGEELVIRA
CCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEEE
AFKPTSTIFKKQNTINLKGEETILEAKGRHDPCVLPRAVPIIEAVVNLVLIDAYLYQRAI
ECCCHHHHHHCCCEEECCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NPQWFQKWARIPDYYKDLEL
CHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
PSSWGKIFKVSTFGESHGTSVGVVVEGVPAGIPIRLEEIQKDLNRRRPGQSNLTTPRDE
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCC
TDTVRVVSGVFEGKTIGSPIALIVDNQNTISKDYENLRTTFRPSHADYTYQMKYGFRAHV
CCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEC
GGGRSSVRETIGRVAAAAIARMILKDDLGIETIAWVDSIGTVQSNIGDKYPKSREEVDQN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
EVRCPDVGSADQMRSLILKMKEAGDSVGGTIQCVSYNLPPGLGDPVYDKLDGDLAKAILS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHH
IPACKGFEVGSGFSGTLLTGSSHNDEFYVEEGTGRVRTRTNHSGGLQGGISNGEELVIRA
CCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEEE
AFKPTSTIFKKQNTINLKGEETILEAKGRHDPCVLPRAVPIIEAVVNLVLIDAYLYQRAI
ECCCHHHHHHCCCEEECCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NPQWFQKWARIPDYYKDLEL
CHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA