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The map label for this gene is mcrB [H]

Identifier: 45359118

GI number: 45359118

Start: 1509697

End: 1511028

Strand: Direct

Name: mcrB [H]

Synonym: MMP1555

Alternate gene names: 45359118

Gene position: 1509697-1511028 (Clockwise)

Preceding gene: 45359113

Following gene: 45359119

Centisome position: 90.88

GC content: 40.47

Gene sequence:

>1332_bases
ATGGTAAAGTATGAAGATAAGATAAGTTTGTACGATGCGAAAGGAAACCTAGTAGCCGAAAATGTACCATTAGAAGCTAT
TAGCCCATTATACAACCCTACCATAAAAAGTATGGTAAAGAACATCAAAAGAACAGTTGCTGTGAACCTAGCTGGTATCG
AAGGTACCTTAGCTGCAGGTAAAATCGGTGGAAAAGGCTGTCAAGTTCCAGGAAGAACTTTAGATATATCTGCAGTAAGC
AATGCTCAAGCAATTGCTGACGAAGTAGAAAAAATCTTAAAAGTATCCGAAGACGACGATACAGCAGTGAAAATAATCAA
CGGTGGAAAACAGTTAGCTGTGCAAGTTCCAACCGCAAGATTGGACGTAGCTGCAGAATACTCAGTATCCATGCTTTCAA
CTGCTATGGCATTAAAAGAAGCACTTATTAAAACATTCAACATCGACATGTTCGATGGTTCAACAGTGCACGCTGCAATT
GTTGGTAACTACCCACAGGTTATGGATTACGCAGGCGGTAACATTGCATCACTCTTAGGTGCACCTTCAATGATGGAAGG
TTTAGGTTACGCTTTAAGAAACATTCCAGTTAACCACGCAGTTGCTACAACCAAGAAAAACATGATGAACGCTATTGCAT
TCTCATCAGTTATGGAACAAACTGCAACATTCGAAATGGGTGACGCAGTAGGATCATTCGAAAGACAGCACTTACTTGGT
TTAGCTTACCAAGGATTAAACGCTGATAACTTAGTTATTGACTTTATTAAAGCAAATGCAAAAGGAACTGTTGGTTCAGT
TGTAGAAACAGTTATTGATAGAGCTATTGCTGACGGCGTAATCGTTGTTGACAAAACAATGAGCTCAGGATTCAACATGT
ACAAACCAGCTGACGTAAACAAATGGAATGCATACGCAGCAGCAGGATTAGTTGCAGCAGTTGCAGTAAGCTGTGGTGCA
GCAAGAGCAGCACAGAACGTTGCTTCAGTTATTTTATACTTCAACGATATTTTAGAGTACGAAACTGGTTTACCTGGTGT
TGACTACGGTAGATCAATGGGTACTGCAGTAGGATTCTCATTCTTCTCACACTCAATCTACGGTGGTGGTGGACCTGGTA
TCTTTAACGGTAACCACGTTGTAACCAGACACTCCAAAGGATTCGCAATTCCTCCAGTATGTGCAGCAATGTGTGCAGAT
GCAGGTACACAAATGTTCTCACCTGAACACACTTCAGGATTAGTTGGTTCAGTATACTCAGCATTTGATGAATTCAGAGA
ACCAATGAAATACGTAATTGAAGGAGCTTTAAGCATTAAAGACCAGTTTTAA

Upstream 100 bases:

>100_bases
AGAGTATATATATTTTTCTATTTGAGTTTAATGAAAACTTGAATATATATTCTTTCAGTAATGTTATGATGTATATATCA
AAAAAATAGGAGTGGTTCCT

Downstream 100 bases:

>100_bases
GGTAATAAACGATGATTGAATTAGAAGTCTTCCCACATAGGTATTTAAAAGCAGAAACTACCGAAAAATTCCTGAACCGC
GCTTATTCATTGAGTAAAGT

Product: methyl-coenzyme M reductase I subunit beta

Products: NA

Alternate protein names: Coenzyme-B sulfoethylthiotransferase beta [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MVKYEDKISLYDAKGNLVAENVPLEAISPLYNPTIKSMVKNIKRTVAVNLAGIEGTLAAGKIGGKGCQVPGRTLDISAVS
NAQAIADEVEKILKVSEDDDTAVKIINGGKQLAVQVPTARLDVAAEYSVSMLSTAMALKEALIKTFNIDMFDGSTVHAAI
VGNYPQVMDYAGGNIASLLGAPSMMEGLGYALRNIPVNHAVATTKKNMMNAIAFSSVMEQTATFEMGDAVGSFERQHLLG
LAYQGLNADNLVIDFIKANAKGTVGSVVETVIDRAIADGVIVVDKTMSSGFNMYKPADVNKWNAYAAAGLVAAVAVSCGA
ARAAQNVASVILYFNDILEYETGLPGVDYGRSMGTAVGFSFFSHSIYGGGGPGIFNGNHVVTRHSKGFAIPPVCAAMCAD
AGTQMFSPEHTSGLVGSVYSAFDEFREPMKYVIEGALSIKDQF

Sequences:

>Translated_443_residues
MVKYEDKISLYDAKGNLVAENVPLEAISPLYNPTIKSMVKNIKRTVAVNLAGIEGTLAAGKIGGKGCQVPGRTLDISAVS
NAQAIADEVEKILKVSEDDDTAVKIINGGKQLAVQVPTARLDVAAEYSVSMLSTAMALKEALIKTFNIDMFDGSTVHAAI
VGNYPQVMDYAGGNIASLLGAPSMMEGLGYALRNIPVNHAVATTKKNMMNAIAFSSVMEQTATFEMGDAVGSFERQHLLG
LAYQGLNADNLVIDFIKANAKGTVGSVVETVIDRAIADGVIVVDKTMSSGFNMYKPADVNKWNAYAAAGLVAAVAVSCGA
ARAAQNVASVILYFNDILEYETGLPGVDYGRSMGTAVGFSFFSHSIYGGGGPGIFNGNHVVTRHSKGFAIPPVCAAMCAD
AGTQMFSPEHTSGLVGSVYSAFDEFREPMKYVIEGALSIKDQF
>Mature_443_residues
MVKYEDKISLYDAKGNLVAENVPLEAISPLYNPTIKSMVKNIKRTVAVNLAGIEGTLAAGKIGGKGCQVPGRTLDISAVS
NAQAIADEVEKILKVSEDDDTAVKIINGGKQLAVQVPTARLDVAAEYSVSMLSTAMALKEALIKTFNIDMFDGSTVHAAI
VGNYPQVMDYAGGNIASLLGAPSMMEGLGYALRNIPVNHAVATTKKNMMNAIAFSSVMEQTATFEMGDAVGSFERQHLLG
LAYQGLNADNLVIDFIKANAKGTVGSVVETVIDRAIADGVIVVDKTMSSGFNMYKPADVNKWNAYAAAGLVAAVAVSCGA
ARAAQNVASVILYFNDILEYETGLPGVDYGRSMGTAVGFSFFSHSIYGGGGPGIFNGNHVVTRHSKGFAIPPVCAAMCAD
AGTQMFSPEHTSGLVGSVYSAFDEFREPMKYVIEGALSIKDQF

Specific function: Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide [H]

COG id: COG4054

COG function: function code H; Methyl coenzyme M reductase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022681
- InterPro:   IPR008924
- InterPro:   IPR015823
- InterPro:   IPR003179
- InterPro:   IPR022679
- InterPro:   IPR022680
- InterPro:   IPR009024 [H]

Pfam domain/function: PF02241 MCR_beta; PF02783 MCR_beta_N [H]

EC number: =2.8.4.1 [H]

Molecular weight: Translated: 46647; Mature: 46647

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKYEDKISLYDAKGNLVAENVPLEAISPLYNPTIKSMVKNIKRTVAVNLAGIEGTLAAG
CCCCCCCEEEEECCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEECC
KIGGKGCQVPGRTLDISAVSNAQAIADEVEKILKVSEDDDTAVKIINGGKQLAVQVPTAR
CCCCCCCCCCCCEEEEHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCHH
LDVAAEYSVSMLSTAMALKEALIKTFNIDMFDGSTVHAAIVGNYPQVMDYAGGNIASLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCHHHHHCCCCCHHHHHC
APSMMEGLGYALRNIPVNHAVATTKKNMMNAIAFSSVMEQTATFEMGDAVGSFERQHLLG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYQGLNADNLVIDFIKANAKGTVGSVVETVIDRAIADGVIVVDKTMSSGFNMYKPADVN
HHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCCC
KWNAYAAAGLVAAVAVSCGAARAAQNVASVILYFNDILEYETGLPGVDYGRSMGTAVGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FFSHSIYGGGGPGIFNGNHVVTRHSKGFAIPPVCAAMCADAGTQMFSPEHTSGLVGSVYS
HHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AFDEFREPMKYVIEGALSIKDQF
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVKYEDKISLYDAKGNLVAENVPLEAISPLYNPTIKSMVKNIKRTVAVNLAGIEGTLAAG
CCCCCCCEEEEECCCCEEECCCCHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEECC
KIGGKGCQVPGRTLDISAVSNAQAIADEVEKILKVSEDDDTAVKIINGGKQLAVQVPTAR
CCCCCCCCCCCCEEEEHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCHH
LDVAAEYSVSMLSTAMALKEALIKTFNIDMFDGSTVHAAIVGNYPQVMDYAGGNIASLLG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCHHHHHCCCCCHHHHHC
APSMMEGLGYALRNIPVNHAVATTKKNMMNAIAFSSVMEQTATFEMGDAVGSFERQHLLG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYQGLNADNLVIDFIKANAKGTVGSVVETVIDRAIADGVIVVDKTMSSGFNMYKPADVN
HHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCCC
KWNAYAAAGLVAAVAVSCGAARAAQNVASVILYFNDILEYETGLPGVDYGRSMGTAVGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FFSHSIYGGGGPGIFNGNHVVTRHSKGFAIPPVCAAMCADAGTQMFSPEHTSGLVGSVYS
HHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AFDEFREPMKYVIEGALSIKDQF
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA