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The map label for this gene is fno [H]

Identifier: 45359113

GI number: 45359113

Start: 1503803

End: 1504474

Strand: Direct

Name: fno [H]

Synonym: MMP1550

Alternate gene names: 45359113

Gene position: 1503803-1504474 (Clockwise)

Preceding gene: 45359112

Following gene: 45359118

Centisome position: 90.53

GC content: 33.93

Gene sequence:

>672_bases
ATGAAGATTGCGATACTTGGTGGAACAGGAGATCAAGGATTTGGCCTTGCACTTAGATTTTCAAAAAATCATGAAATATT
GATCGGATCGAGAAAAGCTGAAAAAGCCATTGAAGCTTCCGAAAATGCTTTGAAAATAATTTCAGATAAAGGATATTCTG
CGGACATTAAAGGAATGACCAATCTTGAAGCTTCAAAATTAGCTGATGTAGTTATTGTATCTTTACCTTTCGAATATACA
ATTTCCACAATAAAAGAATTAAAAGAAGCGTTAAAGGGAAAAATTGTTGTATCAATTGGAGTTCCACTTGCAACAGCAAT
TGGGGACAAACCAACAAGAGTTATTGCATGCCCTCAAGGGTCAGTTGCAGAATTAATTCAAGAAATGCTTCCAGAATCAA
AAGTTGTCAGTGGATTTCAAAATATCTGCTCAAAATGTTTAGAAGACTTAGACTGTGAAGTTGCGTGCGATGTTTTAATT
GCAGGAAATGACAGCGATGCTAAAAAAGTGATTGTTGAACTTGCAAGCGAAATTCCTGGAGTTAGAGGAATTGATGCTGG
AAAATTAGAAATTTCAAAATTTATAGAACAAATTACGCCATTACTAATACAGTTAAACATAAAATACAAATTAAAAGGTG
CTGGAATCCACATTACTGGATTAAACCTTTAA

Upstream 100 bases:

>100_bases
TTTTGAATCTAAAAGTATACGAGATGCGGTAAACAGCAGGGAAACGATAAACAAATATCTATCAATGCTTGAAAAATAAA
ATAAATTAAAAGGTGTGATT

Downstream 100 bases:

>100_bases
TATCGAATTACCATTCCTTTTTTCCAAAAAATAATCGACATTATTGCAAACAATAACCCTAAAAATCTGAGAGTATTTGC
CATTATTAATATCATCTGGT

Product: NADP oxidoreductase, coenzyme F420-dependent

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKIAILGGTGDQGFGLALRFSKNHEILIGSRKAEKAIEASENALKIISDKGYSADIKGMTNLEASKLADVVIVSLPFEYT
ISTIKELKEALKGKIVVSIGVPLATAIGDKPTRVIACPQGSVAELIQEMLPESKVVSGFQNICSKCLEDLDCEVACDVLI
AGNDSDAKKVIVELASEIPGVRGIDAGKLEISKFIEQITPLLIQLNIKYKLKGAGIHITGLNL

Sequences:

>Translated_223_residues
MKIAILGGTGDQGFGLALRFSKNHEILIGSRKAEKAIEASENALKIISDKGYSADIKGMTNLEASKLADVVIVSLPFEYT
ISTIKELKEALKGKIVVSIGVPLATAIGDKPTRVIACPQGSVAELIQEMLPESKVVSGFQNICSKCLEDLDCEVACDVLI
AGNDSDAKKVIVELASEIPGVRGIDAGKLEISKFIEQITPLLIQLNIKYKLKGAGIHITGLNL
>Mature_223_residues
MKIAILGGTGDQGFGLALRFSKNHEILIGSRKAEKAIEASENALKIISDKGYSADIKGMTNLEASKLADVVIVSLPFEYT
ISTIKELKEALKGKIVVSIGVPLATAIGDKPTRVIACPQGSVAELIQEMLPESKVVSGFQNICSKCLEDLDCEVACDVLI
AGNDSDAKKVIVELASEIPGVRGIDAGKLEISKFIEQITPLLIQLNIKYKLKGAGIHITGLNL

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 23716; Mature: 23716

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILGGTGDQGFGLALRFSKNHEILIGSRKAEKAIEASENALKIISDKGYSADIKGMT
CEEEEEECCCCCCCEEEEEECCCCEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCCCC
NLEASKLADVVIVSLPFEYTISTIKELKEALKGKIVVSIGVPLATAIGDKPTRVIACPQG
CCCHHHHHEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCCEEEECCCC
SVAELIQEMLPESKVVSGFQNICSKCLEDLDCEVACDVLIAGNDSDAKKVIVELASEIPG
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
VRGIDAGKLEISKFIEQITPLLIQLNIKYKLKGAGIHITGLNL
CCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCEEEEECCC
>Mature Secondary Structure
MKIAILGGTGDQGFGLALRFSKNHEILIGSRKAEKAIEASENALKIISDKGYSADIKGMT
CEEEEEECCCCCCCEEEEEECCCCEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCCCC
NLEASKLADVVIVSLPFEYTISTIKELKEALKGKIVVSIGVPLATAIGDKPTRVIACPQG
CCCHHHHHEEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCCEEEECCCC
SVAELIQEMLPESKVVSGFQNICSKCLEDLDCEVACDVLIAGNDSDAKKVIVELASEIPG
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
VRGIDAGKLEISKFIEQITPLLIQLNIKYKLKGAGIHITGLNL
CCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]