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The map label for this gene is atoS [H]

Identifier: 42523076

GI number: 42523076

Start: 1496676

End: 1499243

Strand: Direct

Name: atoS [H]

Synonym: Bd1571

Alternate gene names: 42523076

Gene position: 1496676-1499243 (Clockwise)

Preceding gene: 42523075

Following gene: 42523091

Centisome position: 39.56

GC content: 53.43

Gene sequence:

>2568_bases
CTGCATTTCCTGATGGCTCTGTCCGTGCTGGGCATCGCCTCCATCGTGATTTTCGGATGGATTCTGCGGGACCCGGCTCT
GATTCAAATTCGACCTGACTTTGCCCCGATGGTGATCAACACGGCATTGGGGCTGGCCGCTCTGGCCATGGCTCTTCTTT
TTTCGGAAGGGCGCTTTCTACGAATTTCCTTTTTCTCTTCGCTGTTTGCCTTTTTATTGGGGACGATCAACCTGCTTCAG
TATCTGACCGGTATTGATCTGGGCATTGATCAGGCCTTGGTAGAGCCATTTTACAGTGTGGGGGTGGCGTCGCCGGGGCG
CATGTCCATAAGCACATCGGTTTGTATGTTGCTGTTAGGCGTGATGGGTGTGGTGTCGGGTCGTTCTTATGCCCGCCGGA
TGGTGCGAATCACGATCAGTTCTTTGGTGCTTGGGTTTAGTATACTGGGTTTTCTGGGGTACTTCCTGAACTTCAGTTCA
GAGTACGGGTGGGGGGCAATCTCCCGCATGGCGATTCATACCTCGCTGTCCTTCGTTCTGCTGTCATTGGCGCACATTTT
ACAGTTGCGCCGCTCGGTGCGTGATGAAGAATCCGGTCGATCTGCCGTTGTGCCTTTGTATGTGGTTATGATCGGAGTTC
TGACGGCGGTGGGTATCTGGCAGCTGTTGTTGCTGAAGGATATCGAAAGAAACCGCAGCATCACTTTGATTCGTGCTGAA
AGTTTCCGCAGCAAGCTGGATGGAACATTTATTCCCCTTGAAAAAGCCCTGCAGCACATGTCCCGTCGCATGGCCGTGGG
GGCCTATCGTGATGAATCTGTGTGGCGTATGGATGCTCAGTTTTACTACGAGGAATTCAAAGGCATCCGTCGAATTGCGT
GGGCGGATCAGAATCTGCTGTTGCGCTGGCTGTATCCAATGGACGACTTCAGCCGAAATATCCGCAACACCACCATGGGG
CGTTCGGCTGAAATCAGACGCAGTTTGGATATGGCTCGCGAGTCCCATCAATCCCGCATTTCTCGCGTGATTGACATGAA
ATCCGGCGGGCGTGGTTTTGCGCTGCTGGTGCCGGTTTATAAGAACACAGAGTTTGCGGGAATTCTCAGTGCCGGGATCG
AGATTCAGACTTTCCTGGATCGTTTTGCGCGCATTGAAAGTTATCATGTGGCCATTTATGAGGACGGGCAGGAGGTCTAC
CGCAGTTCAGACTGGGATCCTGTGTTGTCGCGGGACTGGCTGACGCGCATCCATTATACCAATATGGGTGTGGATTGGGC
GATCGTCTTTGCACCTTCTACCAGAGCCATTCGCAGCAATACATCGGCGCTGCCTTCGGTGGTGCTGGTTTTTGCCGTGG
GTATTTCCGTTTTGCTGGGGCTGTCGCTCAGCTTTTACAACCGCTCCGATGAAATGCGCAAACGGGCGCGGGCTGTGGCG
GACTGGAAGTCGGCGGCGATGGATGCGACTCCGTTGATGATGATTTCCTTTGATGAACACGGTATTGTTCGGGAGATGAA
TCGCTCAGCGGAAGAAAAGACCGGCTGGAAGACCGAAGAGATCGCTGGAAAAGAGCACCCGTTCATCTTCCATGACCCAC
AGGACGTGGAGCTGATGCGGCTCAGACTTGAAAGCGCACTGAAGCGTCCGGTTGAGCTGGGCGTTGATTTCTTCGAAGCC
ATGTTTGAAGCCGGCTTTAACACCGCTTCAGAGTGGACGTACGTGAATCGCAATGGTTCCCGCTTCCTTGGGCAGTTGTT
CGTCGGAAAAGTCTTTGGTGAAAACGGGGACACGACGGGCTATCTGGCGGTTGTTGAGGACGTCACCCAAAAGCGTCAGC
GGGAAAAACAGATCAAGGAGCAGGAAGACAAGATCATCGCCAGCGCACGCCTGGCCTCGTTGGGTGAAATGGCAGCCGGC
ATCGCCCACGAGATCAACAATCCTTTGACCATCATCAATGGTCACGTCGGTGTTTTACGCCGCCTGCTGGGGGCCCGGGG
GCTTGCCACGGACATTGAAGTGCAAAAGCGCGTTGAAGTCGTCGAAAACACCACCCAGCGCATCGCCAAGATCGTCAAAG
GTTTGCGCTATTATTCCCGGGATTCTGATCCAGGTGATATGGAATGGGTGACAGTGGATGCCATCATTGATGACACACTG
GCGTTTTGTTCAGACAAGTTCCGGCATGAAGGGGTGGACCTGATTGCACGTCTGGAGCCGAACTTGAAGGTGTATGTGCG
GCCGTATCAGATTTCCCAGGTGCTGTTGAATCTATTGAATAATGCGGCGGATGCCGTTCAGTCGGTCAACACCCGTAAGG
TGGTGGTTGAAGCCAAAGGCGTGAAGGACGGTGTCGAGATTTCAATTTCCGATTCCGGTCCGGGAGTGCCAGCGTTTCTG
CGCGATAAAATCATGGAGCCCTTCTTCACGACCAAAGAGGTCGGCATGGGGGTCGGTCTGGGATTGAGCATTTCAGAGGG
GATCGTGCGATCTCATGAAGGCAGATTTTATCTGGATACGGAAGCCAGCCAAACAAGATTTGTGGTCTGGCTTCCTGCTA
AACACTAA

Upstream 100 bases:

>100_bases
GTTCAGAATGCGAGCCAGTTGAACCAGGCGGTGTTTGAAATCCAGAAGATCAAGGGGATCATTGGGGTCACCCGTGTTAT
TCACTAACATCAGGAAGAAT

Downstream 100 bases:

>100_bases
CTACCAGAAATAATTCAGGCGCAGACCCAGCTCTCGAGGTGAGTTGACCTGGTTGTAGCTGACGGACTGACCGCCAATGG
AACTTGTGCGGTCATAGATC

Product: putative sensor protein fixL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 855

Protein sequence:

>855_residues
MHFLMALSVLGIASIVIFGWILRDPALIQIRPDFAPMVINTALGLAALAMALLFSEGRFLRISFFSSLFAFLLGTINLLQ
YLTGIDLGIDQALVEPFYSVGVASPGRMSISTSVCMLLLGVMGVVSGRSYARRMVRITISSLVLGFSILGFLGYFLNFSS
EYGWGAISRMAIHTSLSFVLLSLAHILQLRRSVRDEESGRSAVVPLYVVMIGVLTAVGIWQLLLLKDIERNRSITLIRAE
SFRSKLDGTFIPLEKALQHMSRRMAVGAYRDESVWRMDAQFYYEEFKGIRRIAWADQNLLLRWLYPMDDFSRNIRNTTMG
RSAEIRRSLDMARESHQSRISRVIDMKSGGRGFALLVPVYKNTEFAGILSAGIEIQTFLDRFARIESYHVAIYEDGQEVY
RSSDWDPVLSRDWLTRIHYTNMGVDWAIVFAPSTRAIRSNTSALPSVVLVFAVGISVLLGLSLSFYNRSDEMRKRARAVA
DWKSAAMDATPLMMISFDEHGIVREMNRSAEEKTGWKTEEIAGKEHPFIFHDPQDVELMRLRLESALKRPVELGVDFFEA
MFEAGFNTASEWTYVNRNGSRFLGQLFVGKVFGENGDTTGYLAVVEDVTQKRQREKQIKEQEDKIIASARLASLGEMAAG
IAHEINNPLTIINGHVGVLRRLLGARGLATDIEVQKRVEVVENTTQRIAKIVKGLRYYSRDSDPGDMEWVTVDAIIDDTL
AFCSDKFRHEGVDLIARLEPNLKVYVRPYQISQVLLNLLNNAADAVQSVNTRKVVVEAKGVKDGVEISISDSGPGVPAFL
RDKIMEPFFTTKEVGMGVGLGLSISEGIVRSHEGRFYLDTEASQTRFVVWLPAKH

Sequences:

>Translated_855_residues
MHFLMALSVLGIASIVIFGWILRDPALIQIRPDFAPMVINTALGLAALAMALLFSEGRFLRISFFSSLFAFLLGTINLLQ
YLTGIDLGIDQALVEPFYSVGVASPGRMSISTSVCMLLLGVMGVVSGRSYARRMVRITISSLVLGFSILGFLGYFLNFSS
EYGWGAISRMAIHTSLSFVLLSLAHILQLRRSVRDEESGRSAVVPLYVVMIGVLTAVGIWQLLLLKDIERNRSITLIRAE
SFRSKLDGTFIPLEKALQHMSRRMAVGAYRDESVWRMDAQFYYEEFKGIRRIAWADQNLLLRWLYPMDDFSRNIRNTTMG
RSAEIRRSLDMARESHQSRISRVIDMKSGGRGFALLVPVYKNTEFAGILSAGIEIQTFLDRFARIESYHVAIYEDGQEVY
RSSDWDPVLSRDWLTRIHYTNMGVDWAIVFAPSTRAIRSNTSALPSVVLVFAVGISVLLGLSLSFYNRSDEMRKRARAVA
DWKSAAMDATPLMMISFDEHGIVREMNRSAEEKTGWKTEEIAGKEHPFIFHDPQDVELMRLRLESALKRPVELGVDFFEA
MFEAGFNTASEWTYVNRNGSRFLGQLFVGKVFGENGDTTGYLAVVEDVTQKRQREKQIKEQEDKIIASARLASLGEMAAG
IAHEINNPLTIINGHVGVLRRLLGARGLATDIEVQKRVEVVENTTQRIAKIVKGLRYYSRDSDPGDMEWVTVDAIIDDTL
AFCSDKFRHEGVDLIARLEPNLKVYVRPYQISQVLLNLLNNAADAVQSVNTRKVVVEAKGVKDGVEISISDSGPGVPAFL
RDKIMEPFFTTKEVGMGVGLGLSISEGIVRSHEGRFYLDTEASQTRFVVWLPAKH
>Mature_855_residues
MHFLMALSVLGIASIVIFGWILRDPALIQIRPDFAPMVINTALGLAALAMALLFSEGRFLRISFFSSLFAFLLGTINLLQ
YLTGIDLGIDQALVEPFYSVGVASPGRMSISTSVCMLLLGVMGVVSGRSYARRMVRITISSLVLGFSILGFLGYFLNFSS
EYGWGAISRMAIHTSLSFVLLSLAHILQLRRSVRDEESGRSAVVPLYVVMIGVLTAVGIWQLLLLKDIERNRSITLIRAE
SFRSKLDGTFIPLEKALQHMSRRMAVGAYRDESVWRMDAQFYYEEFKGIRRIAWADQNLLLRWLYPMDDFSRNIRNTTMG
RSAEIRRSLDMARESHQSRISRVIDMKSGGRGFALLVPVYKNTEFAGILSAGIEIQTFLDRFARIESYHVAIYEDGQEVY
RSSDWDPVLSRDWLTRIHYTNMGVDWAIVFAPSTRAIRSNTSALPSVVLVFAVGISVLLGLSLSFYNRSDEMRKRARAVA
DWKSAAMDATPLMMISFDEHGIVREMNRSAEEKTGWKTEEIAGKEHPFIFHDPQDVELMRLRLESALKRPVELGVDFFEA
MFEAGFNTASEWTYVNRNGSRFLGQLFVGKVFGENGDTTGYLAVVEDVTQKRQREKQIKEQEDKIIASARLASLGEMAAG
IAHEINNPLTIINGHVGVLRRLLGARGLATDIEVQKRVEVVENTTQRIAKIVKGLRYYSRDSDPGDMEWVTVDAIIDDTL
AFCSDKFRHEGVDLIARLEPNLKVYVRPYQISQVLLNLLNNAADAVQSVNTRKVVVEAKGVKDGVEISISDSGPGVPAFL
RDKIMEPFFTTKEVGMGVGLGLSISEGIVRSHEGRFYLDTEASQTRFVVWLPAKH

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=346, Percent_Identity=30.635838150289, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=30.9012875536481, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=26.9565217391304, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=25.78125, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 95925; Mature: 95925

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50839 CHASE ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFLMALSVLGIASIVIFGWILRDPALIQIRPDFAPMVINTALGLAALAMALLFSEGRFL
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
RISFFSSLFAFLLGTINLLQYLTGIDLGIDQALVEPFYSVGVASPGRMSISTSVCMLLLG
EHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VMGVVSGRSYARRMVRITISSLVLGFSILGFLGYFLNFSSEYGWGAISRMAIHTSLSFVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LSLAHILQLRRSVRDEESGRSAVVPLYVVMIGVLTAVGIWQLLLLKDIERNRSITLIRAE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SFRSKLDGTFIPLEKALQHMSRRMAVGAYRDESVWRMDAQFYYEEFKGIRRIAWADQNLL
HHHHHHCCCEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LRWLYPMDDFSRNIRNTTMGRSAEIRRSLDMARESHQSRISRVIDMKSGGRGFALLVPVY
EEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
KNTEFAGILSAGIEIQTFLDRFARIESYHVAIYEDGQEVYRSSDWDPVLSRDWLTRIHYT
CCCCHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCCCCCHHHHHHHHHEEE
NMGVDWAIVFAPSTRAIRSNTSALPSVVLVFAVGISVLLGLSLSFYNRSDEMRKRARAVA
CCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DWKSAAMDATPLMMISFDEHGIVREMNRSAEEKTGWKTEEIAGKEHPFIFHDPQDVELMR
HHHHHCCCCCCEEEEEECCCCHHHHHHCCHHHHCCCCCHHHCCCCCCEEEECCCCHHHHH
LRLESALKRPVELGVDFFEAMFEAGFNTASEWTYVNRNGSRFLGQLFVGKVFGENGDTTG
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCE
YLAVVEDVTQKRQREKQIKEQEDKIIASARLASLGEMAAGIAHEINNPLTIINGHVGVLR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
RLLGARGLATDIEVQKRVEVVENTTQRIAKIVKGLRYYSRDSDPGDMEWVTVDAIIDDTL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHH
AFCSDKFRHEGVDLIARLEPNLKVYVRPYQISQVLLNLLNNAADAVQSVNTRKVVVEAKG
HHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
VKDGVEISISDSGPGVPAFLRDKIMEPFFTTKEVGMGVGLGLSISEGIVRSHEGRFYLDT
CCCCCEEEECCCCCCCCHHHHHHHHCCHHCHHHHCCCCCCCCCHHHHHHHCCCCCEEEEC
EASQTRFVVWLPAKH
CCCCEEEEEEECCCC
>Mature Secondary Structure
MHFLMALSVLGIASIVIFGWILRDPALIQIRPDFAPMVINTALGLAALAMALLFSEGRFL
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
RISFFSSLFAFLLGTINLLQYLTGIDLGIDQALVEPFYSVGVASPGRMSISTSVCMLLLG
EHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
VMGVVSGRSYARRMVRITISSLVLGFSILGFLGYFLNFSSEYGWGAISRMAIHTSLSFVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LSLAHILQLRRSVRDEESGRSAVVPLYVVMIGVLTAVGIWQLLLLKDIERNRSITLIRAE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SFRSKLDGTFIPLEKALQHMSRRMAVGAYRDESVWRMDAQFYYEEFKGIRRIAWADQNLL
HHHHHHCCCEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LRWLYPMDDFSRNIRNTTMGRSAEIRRSLDMARESHQSRISRVIDMKSGGRGFALLVPVY
EEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
KNTEFAGILSAGIEIQTFLDRFARIESYHVAIYEDGQEVYRSSDWDPVLSRDWLTRIHYT
CCCCHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCCCCCHHHHHHHHHEEE
NMGVDWAIVFAPSTRAIRSNTSALPSVVLVFAVGISVLLGLSLSFYNRSDEMRKRARAVA
CCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DWKSAAMDATPLMMISFDEHGIVREMNRSAEEKTGWKTEEIAGKEHPFIFHDPQDVELMR
HHHHHCCCCCCEEEEEECCCCHHHHHHCCHHHHCCCCCHHHCCCCCCEEEECCCCHHHHH
LRLESALKRPVELGVDFFEAMFEAGFNTASEWTYVNRNGSRFLGQLFVGKVFGENGDTTG
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCE
YLAVVEDVTQKRQREKQIKEQEDKIIASARLASLGEMAAGIAHEINNPLTIINGHVGVLR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
RLLGARGLATDIEVQKRVEVVENTTQRIAKIVKGLRYYSRDSDPGDMEWVTVDAIIDDTL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHH
AFCSDKFRHEGVDLIARLEPNLKVYVRPYQISQVLLNLLNNAADAVQSVNTRKVVVEAKG
HHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
VKDGVEISISDSGPGVPAFLRDKIMEPFFTTKEVGMGVGLGLSISEGIVRSHEGRFYLDT
CCCCCEEEECCCCCCCCHHHHHHHHCCHHCHHHHCCCCCCCCCHHHHHHHCCCCCEEEEC
EASQTRFVVWLPAKH
CCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]