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The map label for this gene is atoS [H]

Identifier: 42522211

GI number: 42522211

Start: 578419

End: 580341

Strand: Direct

Name: atoS [H]

Synonym: Bd0620

Alternate gene names: 42522211

Gene position: 578419-580341 (Clockwise)

Preceding gene: 42522210

Following gene: 42522212

Centisome position: 15.29

GC content: 51.74

Gene sequence:

>1923_bases
GTGGAGATCATTTTCAGGGCCTCTATTACTGAGGCCCTTTTGCTTTTGCAGAATCAGCGCTTTTCCTCGATCTTAGTCCA
GGAAGTCGGCAACTCCGATGCGTTGGAGTTCCTGTACCAAGCCCGCCTGTTGCAGCCGATGGCTCCGCGTATTTTGATCG
CAGAAGAGCTTAACGAACAGGAAGTCCGTGAGGGCATCAACAAAGCCCAGGTGTATCGTTTCATGCGCTGGCCTTTGACG
GAGCATGAGATCTGGGAACAGCTTGAAAACGCTTTGCAAAAGCACGCGATGTTTCTGTCGCGCTCTTTGCTGCTGAAAGA
ATCCTCGCACCAGAACAAACAGCTGGAAGCTCTGACCCATTCCCTGGAGGGCATGGTTGAAGAGCGCACCCAGTACATTG
AAATGTCCCACCACGAGGAAAGCGAAAAGCTGACCCGGGAGCGCCAGCTGATTCGTTTCATCAAGGATCTGGCGACGCAG
ACGTCGTTTGAAGACATCCTGGCGATCCTGCGTAAGGAGCTTCGCAAGTTCCACAAGATGGGGGATCCGATCTTGGCCTT
CCGCTTGGGTGGATCTAAAACCTTCTTCTTAAGTTTTCAGTCCGGGCATTTTACGCAAACGGAATCTTCGAGTTATTTTG
AATTCCCCAAGACCGCTCAGGTGCCCAGCGCCGAGCTGATTCGCTCGTTTGCCAATCACTTTGGCCGTCCGTTTGTTAAA
GCCTATGTCGTGCCTTTTGAATTGCGTATGACCAGTCACCTGACCAGCGGTGAAGGTGAAGCGATCCTGTGTATTGAAAA
TTCTTTGAACGACAAAGAAATGGGTCCCTTCATGGATTTCATGAATGACCGGGTTCGTCCGCTAAGTATGGCTTTGGATC
GTGTTCTTTTGGAAAACCAGCTTTCCAGTTTCTCGTATCGTTGGGAAAAGACCTTCGATGGCATGCGCGACCCTATCGCG
ATTGTGGACATCGATTACAACGTGGTTCGTGCCAATCGCAAATTCAGTGATCGTTTCATGCATCACAAATGTTATGAAAG
CTTTGCTCACCGCAAGGCCGCTTGTGAAGGCTGCCCGGTGCCTCAGGCTTTGAAAGAAGGCGCGCCGGCCGCAGGCCAGA
TCCAGGTGGATGGGCGCATCTATCAGGTGCACAGTTATCCGGTGCTTTTGGATCAGGGCAGTCGTCCCACGAATATTGTG
AACCAGTATGTGGATATCACCCAGTCCCGCGAACTTTACCTGCGCATGCTGCAAAGTGAAAAAATGGGAGCCATTGGTTT
GCTGGCTGGAAACATCGCCCATGAGCTGAACAATCCTTTAACGGGTCTTCGCTCGTTGTCGCAGGTGCTGCTGCAGGAAG
CCGAAGAGGGCAGCAATCTGCATTCTGATCTGGTCGAGATTGAAAAAGCCACCGCACGATCCCAGCGCATTATTAAAAAC
CTGCTCGATTTCTCGAAAGGGGAAGACCAGCCGTCTGAATATATCAGTGTGGACGAGGTTGTCGAGCGCACTTTGCCGAT
GTTGAAGTCAGCGTTGCGCACCCACCGCCTGGAGGTGGATTTACAAACTTTGGGCTCCACGGTTTATGTGGAGCCGCATT
TGCTGCAACAGGTGGTGTTTAATCTGATTAACAATGCCTGTCAGGCCATGAAAGATCCGGGCCGCTTGAGCTTGCGCACC
AGTTTGGTCAATGGCTCGGTGGTGCTGGAGATTGAAGACACCGGGCCGGGCATTCCGGAAGACATCCGCCGCCGCATCTT
TGAACCCTTCTTTACGACAAAAAAAGAGGGACTTGGTACCGGTCTTGGGTTAAGTATGTCTAAGTCAGTCATTGAAAAAT
TCGGAGGCACCATCGAGTTCCGAAACGTGGATCCCCACGGGACCTGTTTCACGATCGTGCTTCCGCAAAGGAATGCGCCT
TGA

Upstream 100 bases:

>100_bases
GGAAATCAGTTCGATTCCGAACAAGCTCGATCCCATTCTATGGGTCGGAAACGTATCGCCAATTAGACTTCCGCACTTTT
TCCCGTTTCAAAAGCGGGAA

Downstream 100 bases:

>100_bases
AGATTTTAATTGTTGATGATGAAGCTCTGGTCCGCCGCTCTTTGAGCCGTGCCTTGAAAGGCAAGGGTCATGAAGTGCTG
GAGGCCGGTGATGGCAATGA

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MEIIFRASITEALLLLQNQRFSSILVQEVGNSDALEFLYQARLLQPMAPRILIAEELNEQEVREGINKAQVYRFMRWPLT
EHEIWEQLENALQKHAMFLSRSLLLKESSHQNKQLEALTHSLEGMVEERTQYIEMSHHEESEKLTRERQLIRFIKDLATQ
TSFEDILAILRKELRKFHKMGDPILAFRLGGSKTFFLSFQSGHFTQTESSSYFEFPKTAQVPSAELIRSFANHFGRPFVK
AYVVPFELRMTSHLTSGEGEAILCIENSLNDKEMGPFMDFMNDRVRPLSMALDRVLLENQLSSFSYRWEKTFDGMRDPIA
IVDIDYNVVRANRKFSDRFMHHKCYESFAHRKAACEGCPVPQALKEGAPAAGQIQVDGRIYQVHSYPVLLDQGSRPTNIV
NQYVDITQSRELYLRMLQSEKMGAIGLLAGNIAHELNNPLTGLRSLSQVLLQEAEEGSNLHSDLVEIEKATARSQRIIKN
LLDFSKGEDQPSEYISVDEVVERTLPMLKSALRTHRLEVDLQTLGSTVYVEPHLLQQVVFNLINNACQAMKDPGRLSLRT
SLVNGSVVLEIEDTGPGIPEDIRRRIFEPFFTTKKEGLGTGLGLSMSKSVIEKFGGTIEFRNVDPHGTCFTIVLPQRNAP

Sequences:

>Translated_640_residues
MEIIFRASITEALLLLQNQRFSSILVQEVGNSDALEFLYQARLLQPMAPRILIAEELNEQEVREGINKAQVYRFMRWPLT
EHEIWEQLENALQKHAMFLSRSLLLKESSHQNKQLEALTHSLEGMVEERTQYIEMSHHEESEKLTRERQLIRFIKDLATQ
TSFEDILAILRKELRKFHKMGDPILAFRLGGSKTFFLSFQSGHFTQTESSSYFEFPKTAQVPSAELIRSFANHFGRPFVK
AYVVPFELRMTSHLTSGEGEAILCIENSLNDKEMGPFMDFMNDRVRPLSMALDRVLLENQLSSFSYRWEKTFDGMRDPIA
IVDIDYNVVRANRKFSDRFMHHKCYESFAHRKAACEGCPVPQALKEGAPAAGQIQVDGRIYQVHSYPVLLDQGSRPTNIV
NQYVDITQSRELYLRMLQSEKMGAIGLLAGNIAHELNNPLTGLRSLSQVLLQEAEEGSNLHSDLVEIEKATARSQRIIKN
LLDFSKGEDQPSEYISVDEVVERTLPMLKSALRTHRLEVDLQTLGSTVYVEPHLLQQVVFNLINNACQAMKDPGRLSLRT
SLVNGSVVLEIEDTGPGIPEDIRRRIFEPFFTTKKEGLGTGLGLSMSKSVIEKFGGTIEFRNVDPHGTCFTIVLPQRNAP
>Mature_640_residues
MEIIFRASITEALLLLQNQRFSSILVQEVGNSDALEFLYQARLLQPMAPRILIAEELNEQEVREGINKAQVYRFMRWPLT
EHEIWEQLENALQKHAMFLSRSLLLKESSHQNKQLEALTHSLEGMVEERTQYIEMSHHEESEKLTRERQLIRFIKDLATQ
TSFEDILAILRKELRKFHKMGDPILAFRLGGSKTFFLSFQSGHFTQTESSSYFEFPKTAQVPSAELIRSFANHFGRPFVK
AYVVPFELRMTSHLTSGEGEAILCIENSLNDKEMGPFMDFMNDRVRPLSMALDRVLLENQLSSFSYRWEKTFDGMRDPIA
IVDIDYNVVRANRKFSDRFMHHKCYESFAHRKAACEGCPVPQALKEGAPAAGQIQVDGRIYQVHSYPVLLDQGSRPTNIV
NQYVDITQSRELYLRMLQSEKMGAIGLLAGNIAHELNNPLTGLRSLSQVLLQEAEEGSNLHSDLVEIEKATARSQRIIKN
LLDFSKGEDQPSEYISVDEVVERTLPMLKSALRTHRLEVDLQTLGSTVYVEPHLLQQVVFNLINNACQAMKDPGRLSLRT
SLVNGSVVLEIEDTGPGIPEDIRRRIFEPFFTTKKEGLGTGLGLSMSKSVIEKFGGTIEFRNVDPHGTCFTIVLPQRNAP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=32.4894514767932, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=30.9417040358744, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=220, Percent_Identity=30, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=31.2252964426877, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87082128, Length=214, Percent_Identity=28.5046728971963, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=218, Percent_Identity=28.4403669724771, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=27.9816513761468, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=27.8538812785388, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=30.4545454545455, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=26.8085106382979, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=213, Percent_Identity=26.2910798122066, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=30.3964757709251, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=25.9090909090909, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=24.2990654205607, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=379, Percent_Identity=22.6912928759894, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=23.394495412844, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72967; Mature: 72967

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIFRASITEALLLLQNQRFSSILVQEVGNSDALEFLYQARLLQPMAPRILIAEELNEQ
CCEEEEHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCHH
EVREGINKAQVYRFMRWPLTEHEIWEQLENALQKHAMFLSRSLLLKESSHQNKQLEALTH
HHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLEGMVEERTQYIEMSHHEESEKLTRERQLIRFIKDLATQTSFEDILAILRKELRKFHKM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GDPILAFRLGGSKTFFLSFQSGHFTQTESSSYFEFPKTAQVPSAELIRSFANHFGRPFVK
CCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
AYVVPFELRMTSHLTSGEGEAILCIENSLNDKEMGPFMDFMNDRVRPLSMALDRVLLENQ
HEEEEHEEEHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
LSSFSYRWEKTFDGMRDPIAIVDIDYNVVRANRKFSDRFMHHKCYESFAHRKAACEGCPV
HHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQALKEGAPAAGQIQVDGRIYQVHSYPVLLDQGSRPTNIVNQYVDITQSRELYLRMLQSE
CHHHHCCCCCCCEEEECCEEEEEECCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHC
KMGAIGLLAGNIAHELNNPLTGLRSLSQVLLQEAEEGSNLHSDLVEIEKATARSQRIIKN
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLDFSKGEDQPSEYISVDEVVERTLPMLKSALRTHRLEVDLQTLGSTVYVEPHLLQQVVF
HHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEEECHHHHHHHHH
NLINNACQAMKDPGRLSLRTSLVNGSVVLEIEDTGPGIPEDIRRRIFEPFFTTKKEGLGT
HHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHCCCC
GLGLSMSKSVIEKFGGTIEFRNVDPHGTCFTIVLPQRNAP
CCCHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MEIIFRASITEALLLLQNQRFSSILVQEVGNSDALEFLYQARLLQPMAPRILIAEELNEQ
CCEEEEHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCHH
EVREGINKAQVYRFMRWPLTEHEIWEQLENALQKHAMFLSRSLLLKESSHQNKQLEALTH
HHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLEGMVEERTQYIEMSHHEESEKLTRERQLIRFIKDLATQTSFEDILAILRKELRKFHKM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GDPILAFRLGGSKTFFLSFQSGHFTQTESSSYFEFPKTAQVPSAELIRSFANHFGRPFVK
CCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHH
AYVVPFELRMTSHLTSGEGEAILCIENSLNDKEMGPFMDFMNDRVRPLSMALDRVLLENQ
HEEEEHEEEHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
LSSFSYRWEKTFDGMRDPIAIVDIDYNVVRANRKFSDRFMHHKCYESFAHRKAACEGCPV
HHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQALKEGAPAAGQIQVDGRIYQVHSYPVLLDQGSRPTNIVNQYVDITQSRELYLRMLQSE
CHHHHCCCCCCCEEEECCEEEEEECCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHC
KMGAIGLLAGNIAHELNNPLTGLRSLSQVLLQEAEEGSNLHSDLVEIEKATARSQRIIKN
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLDFSKGEDQPSEYISVDEVVERTLPMLKSALRTHRLEVDLQTLGSTVYVEPHLLQQVVF
HHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEEECHHHHHHHHH
NLINNACQAMKDPGRLSLRTSLVNGSVVLEIEDTGPGIPEDIRRRIFEPFFTTKKEGLGT
HHHHHHHHHHCCCCCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHCCCC
GLGLSMSKSVIEKFGGTIEFRNVDPHGTCFTIVLPQRNAP
CCCHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]