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The map label for this gene is arcA [H]

Identifier: 42521988

GI number: 42521988

Start: 349213

End: 349710

Strand: Direct

Name: arcA [H]

Synonym: Bd0374

Alternate gene names: 42521988

Gene position: 349213-349710 (Clockwise)

Preceding gene: 42521987

Following gene: 42521989

Centisome position: 9.23

GC content: 47.39

Gene sequence:

>498_bases
ATGAAGGACAAAAGAATCAACACCAAGGATTTGATCGAAAAGATCGAGAAAATGACCAAGGCCCGCATTGCTTCTCAGGA
AGTGGTGCCTTTGGATCAGTTCCGTGAAGCCAAGAAAAAGCTGGATCCAAAGATCATTCTGGTGATCGAGGATGACGAAA
CCATGCGCCTGGCGATGAAAAGAATCCTTGAGAGTGAAGGTTACGTGACGAAGCTTGCGGCCGATGGCACCGAGCTTTCC
ACAGTGCTGGATGATCACTCGGTGGATCTGATTCTGATGGACGTTGGATTGCCTTGGATCAACGGTTTTGAATTGGCGCA
GTTGCTGAAAGAACACCGCGATCTGAAGAAAATCCCATTGGTGTTCGTGTCCGGCAAAGCTTCTGAAGAAGACATGAAAA
AGGCCTTCGAGATCGGCGCGGATGACTACATCAAAAAGCCATTCGACGTTGAAAAGCTGAAAAAAACCGTGGAAACGCTT
TTGAAGCTGAATCCGTAA

Upstream 100 bases:

>100_bases
CACGTATATCGTCAGGCGATCACGGCAGCCGGTACAGGTTGTATGGCGGCGATCGATGCTGAAAGATGGCTGGAAGCCCA
GGAAGCTCACTAAGGAAGAT

Downstream 100 bases:

>100_bases
CCGGAACGAAAATAGCTTAAAAAATTGGGACCCCTCAGTGAGTGATTGCTGAGGGTTTTTTTATTACAGACCAAAGTTCT
GTCTCAATTCGGGAACACAG

Product: putative transcriptional regulator PhoB-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKDKRINTKDLIEKIEKMTKARIASQEVVPLDQFREAKKKLDPKIILVIEDDETMRLAMKRILESEGYVTKLAADGTELS
TVLDDHSVDLILMDVGLPWINGFELAQLLKEHRDLKKIPLVFVSGKASEEDMKKAFEIGADDYIKKPFDVEKLKKTVETL
LKLNP

Sequences:

>Translated_165_residues
MKDKRINTKDLIEKIEKMTKARIASQEVVPLDQFREAKKKLDPKIILVIEDDETMRLAMKRILESEGYVTKLAADGTELS
TVLDDHSVDLILMDVGLPWINGFELAQLLKEHRDLKKIPLVFVSGKASEEDMKKAFEIGADDYIKKPFDVEKLKKTVETL
LKLNP
>Mature_165_residues
MKDKRINTKDLIEKIEKMTKARIASQEVVPLDQFREAKKKLDPKIILVIEDDETMRLAMKRILESEGYVTKLAADGTELS
TVLDDHSVDLILMDVGLPWINGFELAQLLKEHRDLKKIPLVFVSGKASEEDMKKAFEIGADDYIKKPFDVEKLKKTVETL
LKLNP

Specific function: Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=39.3162393162393, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=119, Percent_Identity=32.7731092436975, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790860, Length=118, Percent_Identity=33.0508474576271, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=30.2521008403361, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=27.1186440677966, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=116, Percent_Identity=30.1724137931034, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=26.3157894736842, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=31.9327731092437, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 18880; Mature: 18880

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKRINTKDLIEKIEKMTKARIASQEVVPLDQFREAKKKLDPKIILVIEDDETMRLAMK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RILESEGYVTKLAADGTELSTVLDDHSVDLILMDVGLPWINGFELAQLLKEHRDLKKIPL
HHHHCCCCEEEEECCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCE
VFVSGKASEEDMKKAFEIGADDYIKKPFDVEKLKKTVETLLKLNP
EEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDKRINTKDLIEKIEKMTKARIASQEVVPLDQFREAKKKLDPKIILVIEDDETMRLAMK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RILESEGYVTKLAADGTELSTVLDDHSVDLILMDVGLPWINGFELAQLLKEHRDLKKIPL
HHHHCCCCEEEEECCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCE
VFVSGKASEEDMKKAFEIGADDYIKKPFDVEKLKKTVETLLKLNP
EEEECCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]