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The map label for this gene is trxB [H]

Identifier: 42521987

GI number: 42521987

Start: 348261

End: 349205

Strand: Direct

Name: trxB [H]

Synonym: Bd0373

Alternate gene names: 42521987

Gene position: 348261-349205 (Clockwise)

Preceding gene: 42521985

Following gene: 42521988

Centisome position: 9.21

GC content: 51.85

Gene sequence:

>945_bases
ATGACTCAGGATCAAAAAGTTGAAAACGTCATCATCATCGGTTCCGGCCCTGCAGGCCTGACTTCCGCTATCTATTCTTC
CCGCGCCAATCTGGAGCCTTTGATGATCGAAGGTGAAGAGGCCGGCGGTCAGCTGATGACCACGACCGAAGTTGAAAACT
TCCCGGGCTTTGACCACGGGATCACGGGTCCTGACCTGATCACGGTCATGAGAAAACAGGCTGAAAGATTCGGCACGCGT
TTTATCACTCGTAACGTGACGAAAGTGGATTTTTCCCAGCGTCCGTTCAAAGTGTGGATCGGTGACAAACTTCACCTGGC
AAAATCCATCATCATCTCTACCGGCGCCAGCGCGAAGTATCTGGGCCTGCCTTCTGAAAAAGTTTACGCCAACCGCGGTG
TTTCCGCGTGTGCAACGTGTGATGGTGCCTTCTTCCGCAATCAGGAAATCGGCGTTGTTGGCGGTGGTGACACGGCGATG
GAAGAAGCTCAGTTCCTGACTCGTTTTGCGACCAAAGTGTATCTGATCCACAGACGTGACCATTTCCGTGCTTCCAAGAT
CATGGTGGACCGTGCTTTGAAGAACCCAAAAATCGAAGTGCTTTACAACACTGAGGTGATCGAGGTTCTGGGGGACGGCA
AGGGTATGACCGGCGCAAAAATCAAAGGCACTCTTGATGGCGCTGTCAAAGAACTTCCGATCACAGGTCTATTCCTGGCC
ATTGGCCATAAGCCGAACACCGACCTTTTTAAAGGTGTTTTGGATATGAATGAGACAGGCTATTTGATCACCCAGCCCAA
CACCACGTATACTAACATTCCAGGTGTCTTTGCGGCGGGAGACGTGCAAGATCACGTATATCGTCAGGCGATCACGGCAG
CCGGTACAGGTTGTATGGCGGCGATCGATGCTGAAAGATGGCTGGAAGCCCAGGAAGCTCACTAA

Upstream 100 bases:

>100_bases
TGTAGCTGACGCAGTCCAAAACGTGCAAAGAAGTAATGAAAACGGGGCTATTTGTGGTAGCCTTGATCCGTTATTGTCCC
GACCAATTGTGAGGTAATCT

Downstream 100 bases:

>100_bases
GGAAGATATGAAGGACAAAAGAATCAACACCAAGGATTTGATCGAAAAGATCGAGAAAATGACCAAGGCCCGCATTGCTT
CTCAGGAAGTGGTGCCTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTQDQKVENVIIIGSGPAGLTSAIYSSRANLEPLMIEGEEAGGQLMTTTEVENFPGFDHGITGPDLITVMRKQAERFGTR
FITRNVTKVDFSQRPFKVWIGDKLHLAKSIIISTGASAKYLGLPSEKVYANRGVSACATCDGAFFRNQEIGVVGGGDTAM
EEAQFLTRFATKVYLIHRRDHFRASKIMVDRALKNPKIEVLYNTEVIEVLGDGKGMTGAKIKGTLDGAVKELPITGLFLA
IGHKPNTDLFKGVLDMNETGYLITQPNTTYTNIPGVFAAGDVQDHVYRQAITAAGTGCMAAIDAERWLEAQEAH

Sequences:

>Translated_314_residues
MTQDQKVENVIIIGSGPAGLTSAIYSSRANLEPLMIEGEEAGGQLMTTTEVENFPGFDHGITGPDLITVMRKQAERFGTR
FITRNVTKVDFSQRPFKVWIGDKLHLAKSIIISTGASAKYLGLPSEKVYANRGVSACATCDGAFFRNQEIGVVGGGDTAM
EEAQFLTRFATKVYLIHRRDHFRASKIMVDRALKNPKIEVLYNTEVIEVLGDGKGMTGAKIKGTLDGAVKELPITGLFLA
IGHKPNTDLFKGVLDMNETGYLITQPNTTYTNIPGVFAAGDVQDHVYRQAITAAGTGCMAAIDAERWLEAQEAH
>Mature_313_residues
TQDQKVENVIIIGSGPAGLTSAIYSSRANLEPLMIEGEEAGGQLMTTTEVENFPGFDHGITGPDLITVMRKQAERFGTRF
ITRNVTKVDFSQRPFKVWIGDKLHLAKSIIISTGASAKYLGLPSEKVYANRGVSACATCDGAFFRNQEIGVVGGGDTAME
EAQFLTRFATKVYLIHRRDHFRASKIMVDRALKNPKIEVLYNTEVIEVLGDGKGMTGAKIKGTLDGAVKELPITGLFLAI
GHKPNTDLFKGVLDMNETGYLITQPNTTYTNIPGVFAAGDVQDHVYRQAITAAGTGCMAAIDAERWLEAQEAH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=52.2435897435897, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=31.4935064935065, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=52.6984126984127, Blast_Score=339, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=52.8662420382166, Blast_Score=337, Evalue=2e-93,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34117; Mature: 33986

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDQKVENVIIIGSGPAGLTSAIYSSRANLEPLMIEGEEAGGQLMTTTEVENFPGFDHG
CCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCC
ITGPDLITVMRKQAERFGTRFITRNVTKVDFSQRPFKVWIGDKLHLAKSIIISTGASAKY
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHHEEEEECCCCEEE
LGLPSEKVYANRGVSACATCDGAFFRNQEIGVVGGGDTAMEEAQFLTRFATKVYLIHRRD
ECCCCHHHHHCCCCCCEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHEEEEEECCC
HFRASKIMVDRALKNPKIEVLYNTEVIEVLGDGKGMTGAKIKGTLDGAVKELPITGLFLA
CCHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCEEEECCCCHHHHCCCEEEEEE
IGHKPNTDLFKGVLDMNETGYLITQPNTTYTNIPGVFAAGDVQDHVYRQAITAAGTGCMA
ECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEE
AIDAERWLEAQEAH
EECHHHHHHHHCCC
>Mature Secondary Structure 
TQDQKVENVIIIGSGPAGLTSAIYSSRANLEPLMIEGEEAGGQLMTTTEVENFPGFDHG
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCC
ITGPDLITVMRKQAERFGTRFITRNVTKVDFSQRPFKVWIGDKLHLAKSIIISTGASAKY
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHHEEEEECCCCEEE
LGLPSEKVYANRGVSACATCDGAFFRNQEIGVVGGGDTAMEEAQFLTRFATKVYLIHRRD
ECCCCHHHHHCCCCCCEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHEEEEEECCC
HFRASKIMVDRALKNPKIEVLYNTEVIEVLGDGKGMTGAKIKGTLDGAVKELPITGLFLA
CCHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCEEEECCCCHHHHCCCEEEEEE
IGHKPNTDLFKGVLDMNETGYLITQPNTTYTNIPGVFAAGDVQDHVYRQAITAAGTGCMA
ECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEE
AIDAERWLEAQEAH
EECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]