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The map label for this gene is plsC [H]

Identifier: 42521968

GI number: 42521968

Start: 330113

End: 330877

Strand: Direct

Name: plsC [H]

Synonym: Bd0348

Alternate gene names: 42521968

Gene position: 330113-330877 (Clockwise)

Preceding gene: 42521967

Following gene: 42521969

Centisome position: 8.73

GC content: 53.59

Gene sequence:

>765_bases
ATGTTGTGGTCGTATATCTGCCATCTGGTGGTGCGCGACCCGCAGAAAAGGCTTCAGCGCTTTTCAAATAACTCGCGCTT
TTTCTCGGGCCTGATTCTGAAGGTTTTCAATCTGGATCTGACGGTCATCAACAAGCCGGCAAGTGATCAGAAATGTCTGA
TTGTTTCCAATCACATGGGTTTCGTCGATATTCTGATGCTGGCGTCCTGTCACCCGATGCTGTTTGTGACTTCCAATGAA
ATGCGTGAAACCCCGTTCCTGGGTCTTTTGACCGAGATGGGTGGTTGCATTTACGTCGAGCGCCGCAGCCGCACAAAAAT
TCTGGATGAAATGAAGTCCATCGTGAATGCCCTGCGCGCCGGCTTCCGTGTGGTGCTTTATCCGGAAGCGACGTCCACCA
ATGGCGAGCGTGTGTTGCCGTTCAAAAAGACCCTGATGATGGCGGCGGCTCAGGCTGGCGTGCCGATTCAGCCGGTGGTG
ATCAACTTCCGTGAGGTGAATGGTGAAGAGTTCAGCCTTAAATGGCGTGATCATCTTTGTTGGTATGGTGATATTCCCTT
CGCGACGTCGATGTGGAAGTCTGCGATCCTGAAGTCTGTGAAAGGTGAGATCGAATTCCTGGAGCCGATTTACGCGACCC
CGGATGATGATCGGGGCCTGATTGCCGACAAAGCCCACGCGGCCATTTCGGCTAAGTTCGTTCCGGTCAAAGGTCTTCCG
GCAGAGCCCCAGCCTCCGGCCGAGATGCAGGCAGATCCCACTTGA

Upstream 100 bases:

>100_bases
TCCATCGGGAAGATTTAAATAGGACCCTGTGGAAGCGATTCAAGCTGGACTCCGCGGAGTCCTAAAACTTACTGTCTTTG
TTCTGATTATCCTGACATTC

Downstream 100 bases:

>100_bases
TTTAGTCCGTCCGATATGTAAATAATGTGTAAATGAGGAAGATCATTCACATCGACATGGACTGCTTTTACGCGGCTGTG
GAAGTGAAGTACCGTCCCGA

Product: acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLWSYICHLVVRDPQKRLQRFSNNSRFFSGLILKVFNLDLTVINKPASDQKCLIVSNHMGFVDILMLASCHPMLFVTSNE
MRETPFLGLLTEMGGCIYVERRSRTKILDEMKSIVNALRAGFRVVLYPEATSTNGERVLPFKKTLMMAAAQAGVPIQPVV
INFREVNGEEFSLKWRDHLCWYGDIPFATSMWKSAILKSVKGEIEFLEPIYATPDDDRGLIADKAHAAISAKFVPVKGLP
AEPQPPAEMQADPT

Sequences:

>Translated_254_residues
MLWSYICHLVVRDPQKRLQRFSNNSRFFSGLILKVFNLDLTVINKPASDQKCLIVSNHMGFVDILMLASCHPMLFVTSNE
MRETPFLGLLTEMGGCIYVERRSRTKILDEMKSIVNALRAGFRVVLYPEATSTNGERVLPFKKTLMMAAAQAGVPIQPVV
INFREVNGEEFSLKWRDHLCWYGDIPFATSMWKSAILKSVKGEIEFLEPIYATPDDDRGLIADKAHAAISAKFVPVKGLP
AEPQPPAEMQADPT
>Mature_254_residues
MLWSYICHLVVRDPQKRLQRFSNNSRFFSGLILKVFNLDLTVINKPASDQKCLIVSNHMGFVDILMLASCHPMLFVTSNE
MRETPFLGLLTEMGGCIYVERRSRTKILDEMKSIVNALRAGFRVVLYPEATSTNGERVLPFKKTLMMAAAQAGVPIQPVV
INFREVNGEEFSLKWRDHLCWYGDIPFATSMWKSAILKSVKGEIEFLEPIYATPDDDRGLIADKAHAAISAKFVPVKGLP
AEPQPPAEMQADPT

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Drosophila melanogaster, GI281364648, Length=119, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582856, Length=119, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582854, Length=119, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28592; Mature: 28592

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSYICHLVVRDPQKRLQRFSNNSRFFSGLILKVFNLDLTVINKPASDQKCLIVSNHMG
CHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCC
FVDILMLASCHPMLFVTSNEMRETPFLGLLTEMGGCIYVERRSRTKILDEMKSIVNALRA
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHC
GFRVVLYPEATSTNGERVLPFKKTLMMAAAQAGVPIQPVVINFREVNGEEFSLKWRDHLC
CCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCEE
WYGDIPFATSMWKSAILKSVKGEIEFLEPIYATPDDDRGLIADKAHAAISAKFVPVKGLP
EECCCCHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCCCEECCCCCEEEEEEEEECCCC
AEPQPPAEMQADPT
CCCCCCCCCCCCCC
>Mature Secondary Structure
MLWSYICHLVVRDPQKRLQRFSNNSRFFSGLILKVFNLDLTVINKPASDQKCLIVSNHMG
CHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCC
FVDILMLASCHPMLFVTSNEMRETPFLGLLTEMGGCIYVERRSRTKILDEMKSIVNALRA
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHC
GFRVVLYPEATSTNGERVLPFKKTLMMAAAQAGVPIQPVVINFREVNGEEFSLKWRDHLC
CCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCEE
WYGDIPFATSMWKSAILKSVKGEIEFLEPIYATPDDDRGLIADKAHAAISAKFVPVKGLP
EECCCCHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCCCEECCCCCEEEEEEEEECCCC
AEPQPPAEMQADPT
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8748025 [H]