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The map label for this gene is dinP [H]

Identifier: 42521969

GI number: 42521969

Start: 330910

End: 331980

Strand: Direct

Name: dinP [H]

Synonym: Bd0349

Alternate gene names: 42521969

Gene position: 330910-331980 (Clockwise)

Preceding gene: 42521968

Following gene: 42521970

Centisome position: 8.75

GC content: 52.66

Gene sequence:

>1071_bases
ATGAGGAAGATCATTCACATCGACATGGACTGCTTTTACGCGGCTGTGGAAGTGAAGTACCGTCCCGAACTCAAAGGCAA
ACCTTTGGGGATCGGCGGTCCACCGAACACCCGCAGCGTGCTGTGCACCGCGAGCTATGAAGCCCGCAAGTTCGGCGTGC
GTTCGGCAATGCCCTCTTCGCAAGCGGTACGTCTGTGCCCGCAGCTGGTTTTGATTCCTCCACATTTTGACTTATATAAA
GCTGAAAGCCGCAAAGTCCGTGAAATCATGGAAAGATTCACAAACAAGATTGAGCCTTTGTCCCTGGATGAAGCCTATCT
GGATGTGACCGATTGTGAGCAGTTCGGTGGCAGTGCCACCCTGATTGCGCAGGAAATCCGTCGTTTGATCTTTACCGAAC
TGAACCTGACGGCGTCCGCCGGGGTGGCGCCGAACAAGTTTCTGGCCAAGATCGCCAGTGACTGGAAAAAGCCCAACGGG
CAGTTCGTGGTCAGACCTCAGGATGTGGAAACTTTTGTGAAAGACCTGCCGGTTGAAAAGATCTTCGGAGTGGGCAAAGT
CACCGCCCAGAAGATGCATGATCTGGGGCTTCGCACGTGTGGTGATATTCAGAAATACACCGTTCTTGAATTGTCGCATT
GGTTTGGATCGCGCGCGGCGGAGCTTTATGATTTTTCCCGCGGCATAGATCATCGCGAAGTGATCACCGAGTGGGAGCGC
AAATCGCTGACGGTGGAGGAAACTTACAACAAGGATCTTCCCACGTTGCAGGATTGTTTAAAGACGTTGCCGTCACTTTA
CGAGGACTTTGTGCGCCGGATGGATCGTGGGCAGTATCACGATCGCATCAAGGGTCTGGTGATCAAGCTGAAGTTCTTCG
ATTTCAAACAAACCACGCATGAAGAAGTCATCAGCGAGCTTCCCACGTTGCAGGATTTTGAACGCCTGCTGGAAAAGGCC
TGGAATCGCCGGGGTGTGCCGGTGCGCCTGGTGGGCTTGGGGGTTCGCTTGGGCACACAAAAGAAATTTTCCTCGGAATC
CGATTCTTCTCAGTTGAAGTTTGCCATTTAG

Upstream 100 bases:

>100_bases
TCGTTCCGGTCAAAGGTCTTCCGGCAGAGCCCCAGCCTCCGGCCGAGATGCAGGCAGATCCCACTTGATTTAGTCCGTCC
GATATGTAAATAATGTGTAA

Downstream 100 bases:

>100_bases
TTGTAAATCACGGTTGGAAACAGGTGGTGCATTTTTTTCTGGCATCACTGTTGCTTTAACAGTCCTTTGCCCACCAGCGG
GGCCACAACGGCTTCGTTTG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRKIIHIDMDCFYAAVEVKYRPELKGKPLGIGGPPNTRSVLCTASYEARKFGVRSAMPSSQAVRLCPQLVLIPPHFDLYK
AESRKVREIMERFTNKIEPLSLDEAYLDVTDCEQFGGSATLIAQEIRRLIFTELNLTASAGVAPNKFLAKIASDWKKPNG
QFVVRPQDVETFVKDLPVEKIFGVGKVTAQKMHDLGLRTCGDIQKYTVLELSHWFGSRAAELYDFSRGIDHREVITEWER
KSLTVEETYNKDLPTLQDCLKTLPSLYEDFVRRMDRGQYHDRIKGLVIKLKFFDFKQTTHEEVISELPTLQDFERLLEKA
WNRRGVPVRLVGLGVRLGTQKKFSSESDSSQLKFAI

Sequences:

>Translated_356_residues
MRKIIHIDMDCFYAAVEVKYRPELKGKPLGIGGPPNTRSVLCTASYEARKFGVRSAMPSSQAVRLCPQLVLIPPHFDLYK
AESRKVREIMERFTNKIEPLSLDEAYLDVTDCEQFGGSATLIAQEIRRLIFTELNLTASAGVAPNKFLAKIASDWKKPNG
QFVVRPQDVETFVKDLPVEKIFGVGKVTAQKMHDLGLRTCGDIQKYTVLELSHWFGSRAAELYDFSRGIDHREVITEWER
KSLTVEETYNKDLPTLQDCLKTLPSLYEDFVRRMDRGQYHDRIKGLVIKLKFFDFKQTTHEEVISELPTLQDFERLLEKA
WNRRGVPVRLVGLGVRLGTQKKFSSESDSSQLKFAI
>Mature_356_residues
MRKIIHIDMDCFYAAVEVKYRPELKGKPLGIGGPPNTRSVLCTASYEARKFGVRSAMPSSQAVRLCPQLVLIPPHFDLYK
AESRKVREIMERFTNKIEPLSLDEAYLDVTDCEQFGGSATLIAQEIRRLIFTELNLTASAGVAPNKFLAKIASDWKKPNG
QFVVRPQDVETFVKDLPVEKIFGVGKVTAQKMHDLGLRTCGDIQKYTVLELSHWFGSRAAELYDFSRGIDHREVITEWER
KSLTVEETYNKDLPTLQDCLKTLPSLYEDFVRRMDRGQYHDRIKGLVIKLKFFDFKQTTHEEVISELPTLQDFERLLEKA
WNRRGVPVRLVGLGVRLGTQKKFSSESDSSQLKFAI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=325, Percent_Identity=30.4615384615385, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI7706681, Length=326, Percent_Identity=30.3680981595092, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI154350220, Length=288, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=53.2710280373832, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI5729982, Length=128, Percent_Identity=36.71875, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786425, Length=339, Percent_Identity=53.3923303834808, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1787432, Length=209, Percent_Identity=28.7081339712919, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=401, Percent_Identity=29.6758104738155, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=257, Percent_Identity=30.7392996108949, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=346, Percent_Identity=28.0346820809249, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324921, Length=271, Percent_Identity=27.3062730627306, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=28.1733746130031, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355641, Length=351, Percent_Identity=28.7749287749288, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=351, Percent_Identity=28.7749287749288, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40738; Mature: 40738

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCFYAAVEVKYRPELKGKPLGIGGPPNTRSVLCTASYEARKFGVRSAMPSS
CCEEEEECHHHEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCH
QAVRLCPQLVLIPPHFDLYKAESRKVREIMERFTNKIEPLSLDEAYLDVTDCEQFGGSAT
HHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHCCCCHH
LIAQEIRRLIFTELNLTASAGVAPNKFLAKIASDWKKPNGQFVVRPQDVETFVKDLPVEK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCHHH
IFGVGKVTAQKMHDLGLRTCGDIQKYTVLELSHWFGSRAAELYDFSRGIDHREVITEWER
HHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
KSLTVEETYNKDLPTLQDCLKTLPSLYEDFVRRMDRGQYHDRIKGLVIKLKFFDFKQTTH
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEEEEEECCHHHHH
EEVISELPTLQDFERLLEKAWNRRGVPVRLVGLGVRLGTQKKFSSESDSSQLKFAI
HHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECEEECCCHHCCCCCCCCCEEEEC
>Mature Secondary Structure
MRKIIHIDMDCFYAAVEVKYRPELKGKPLGIGGPPNTRSVLCTASYEARKFGVRSAMPSS
CCEEEEECHHHEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCH
QAVRLCPQLVLIPPHFDLYKAESRKVREIMERFTNKIEPLSLDEAYLDVTDCEQFGGSAT
HHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHCCCCHH
LIAQEIRRLIFTELNLTASAGVAPNKFLAKIASDWKKPNGQFVVRPQDVETFVKDLPVEK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCHHH
IFGVGKVTAQKMHDLGLRTCGDIQKYTVLELSHWFGSRAAELYDFSRGIDHREVITEWER
HHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
KSLTVEETYNKDLPTLQDCLKTLPSLYEDFVRRMDRGQYHDRIKGLVIKLKFFDFKQTTH
HCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEEEEEECCHHHHH
EEVISELPTLQDFERLLEKAWNRRGVPVRLVGLGVRLGTQKKFSSESDSSQLKFAI
HHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECEEECCCHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA