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The map label for this gene is ywlC [H]

Identifier: 42521964

GI number: 42521964

Start: 326676

End: 327692

Strand: Direct

Name: ywlC [H]

Synonym: Bd0344

Alternate gene names: 42521964

Gene position: 326676-327692 (Clockwise)

Preceding gene: 42521963

Following gene: 42521967

Centisome position: 8.64

GC content: 53.59

Gene sequence:

>1017_bases
ATGATGTCGCCAAACGAGGCCTTGGCCAAAGCCAAAATCATACTTGAAGAAGGGGGAGTCATCGGCTTCCCCACCGAGAC
CGTTTACGGTCTGGCGGCCCGTATTGATATCCCTTCGGCCATCGAAAAGATTTTTACCACCAAAGAGCGTCCGTTCTTTG
ATCCCTTGATTGTGCATGTGGCGTCCATTGAACAGGCCAAGAAGGTCACGGCCTTCTGGGGACCGGCTTCTCAGGCGCTG
GCGGAAGCTTTCTGGCCGGGTCCGCTGACCATGGTGCTGCCACGGGATCCTTCCGTAAATGCGATGATCACGTCGGGTCT
TGAATCCGTGGGCATTCGCATGCCAAATCACCCGCTGGCTTTGGAACTGTTGCAGCAGGTGGGTGTGCCTTTGGCGGCGC
CAAGTGCCAACAAGTTCGGTCGCACCTCCCCGACGTCCGCGTCCCATGTGCGGGTGGAATTTAAAAATGAAAACGTTTTC
GTGGTTGATGGTGGCGATTGTGAAATCGGCATCGAATCCACGGTCTTGCTGGTTCGTCACCGTCCTGAAGGTGTGATGCT
GTCGATTCTTCGCCGCGGGCATATTCTGAAATCAGATCTTGCGCGTGTGCTGGAAGAAAAGGGCCTGGCTTATGAATTCA
TCGAGCAGGTGGATAAGCGCGAATCCCCAGGCCATATGAAACATCACTATATGCCGCCAGTTCCGCTGGTGGTGTGTCTG
GATCCGTCCCGCAGCCCGGAAAGTGTGCTGAAAGAAGTGAATGAAAAGATCGGCGAACTGCCGGATGAAATTGAAAGCAT
CAAGATCATCAAACCTAAAGCGGGCATTCATTCCTACGAGGTTTTAAAACTTTCCGAAGACCCGTTGCTGGCAACACGTG
AATTCTATGGTCACTTGCGTGACGTGGCTGCGCGCGGGAAAGATTGCATTCTGTTTTACCGTGAAGCCCACCAAACCGGT
GAGCGCTGGGAATCCCTGTTTGACCGCCTGAATAAAGCGGCCTCTCTTATTGTCTGA

Upstream 100 bases:

>100_bases
AGTCTGGATATCGTGCGTGAAAGCGCCCTGAGCATCCTGCGGGAAGAAAAATAGACGGGAAACCTTTCAATCCCGTCTGC
TTTGATGTACAAAAGTATCC

Downstream 100 bases:

>100_bases
GTTTTCTTTGCAAACGGAAAGTCAAAGCCGGAACCATGGAGGTGATTATCGCCATGGCAACAAGGCTTGTGAACAAAGTC
ATGTCAATCAGTCCGGCCTT

Product: putative translation factor related to Sua5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMSPNEALAKAKIILEEGGVIGFPTETVYGLAARIDIPSAIEKIFTTKERPFFDPLIVHVASIEQAKKVTAFWGPASQAL
AEAFWPGPLTMVLPRDPSVNAMITSGLESVGIRMPNHPLALELLQQVGVPLAAPSANKFGRTSPTSASHVRVEFKNENVF
VVDGGDCEIGIESTVLLVRHRPEGVMLSILRRGHILKSDLARVLEEKGLAYEFIEQVDKRESPGHMKHHYMPPVPLVVCL
DPSRSPESVLKEVNEKIGELPDEIESIKIIKPKAGIHSYEVLKLSEDPLLATREFYGHLRDVAARGKDCILFYREAHQTG
ERWESLFDRLNKAASLIV

Sequences:

>Translated_338_residues
MMSPNEALAKAKIILEEGGVIGFPTETVYGLAARIDIPSAIEKIFTTKERPFFDPLIVHVASIEQAKKVTAFWGPASQAL
AEAFWPGPLTMVLPRDPSVNAMITSGLESVGIRMPNHPLALELLQQVGVPLAAPSANKFGRTSPTSASHVRVEFKNENVF
VVDGGDCEIGIESTVLLVRHRPEGVMLSILRRGHILKSDLARVLEEKGLAYEFIEQVDKRESPGHMKHHYMPPVPLVVCL
DPSRSPESVLKEVNEKIGELPDEIESIKIIKPKAGIHSYEVLKLSEDPLLATREFYGHLRDVAARGKDCILFYREAHQTG
ERWESLFDRLNKAASLIV
>Mature_338_residues
MMSPNEALAKAKIILEEGGVIGFPTETVYGLAARIDIPSAIEKIFTTKERPFFDPLIVHVASIEQAKKVTAFWGPASQAL
AEAFWPGPLTMVLPRDPSVNAMITSGLESVGIRMPNHPLALELLQQVGVPLAAPSANKFGRTSPTSASHVRVEFKNENVF
VVDGGDCEIGIESTVLLVRHRPEGVMLSILRRGHILKSDLARVLEEKGLAYEFIEQVDKRESPGHMKHHYMPPVPLVVCL
DPSRSPESVLKEVNEKIGELPDEIESIKIIKPKAGIHSYEVLKLSEDPLLATREFYGHLRDVAARGKDCILFYREAHQTG
ERWESLFDRLNKAASLIV

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=151, Percent_Identity=31.7880794701987, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537239, Length=161, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=372, Percent_Identity=29.0322580645161, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 37406; Mature: 37406

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPNEALAKAKIILEEGGVIGFPTETVYGLAARIDIPSAIEKIFTTKERPFFDPLIVHV
CCCCHHHHHHHEEEEECCCEEECCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHH
ASIEQAKKVTAFWGPASQALAEAFWPGPLTMVLPRDPSVNAMITSGLESVGIRMPNHPLA
HHHHHHHHEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCHHHHCCCCCCCCHH
LELLQQVGVPLAAPSANKFGRTSPTSASHVRVEFKNENVFVVDGGDCEIGIESTVLLVRH
HHHHHHCCCCEECCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEECCCCEEEEEEE
RPEGVMLSILRRGHILKSDLARVLEEKGLAYEFIEQVDKRESPGHMKHHYMPPVPLVVCL
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
DPSRSPESVLKEVNEKIGELPDEIESIKIIKPKAGIHSYEVLKLSEDPLLATREFYGHLR
CCCCCHHHHHHHHHHHHCCCCHHHHCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHH
DVAARGKDCILFYREAHQTGERWESLFDRLNKAASLIV
HHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSPNEALAKAKIILEEGGVIGFPTETVYGLAARIDIPSAIEKIFTTKERPFFDPLIVHV
CCCCHHHHHHHEEEEECCCEEECCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHH
ASIEQAKKVTAFWGPASQALAEAFWPGPLTMVLPRDPSVNAMITSGLESVGIRMPNHPLA
HHHHHHHHEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCHHHHCCCCCCCCHH
LELLQQVGVPLAAPSANKFGRTSPTSASHVRVEFKNENVFVVDGGDCEIGIESTVLLVRH
HHHHHHCCCCEECCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEECCCCEEEEEEE
RPEGVMLSILRRGHILKSDLARVLEEKGLAYEFIEQVDKRESPGHMKHHYMPPVPLVVCL
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
DPSRSPESVLKEVNEKIGELPDEIESIKIIKPKAGIHSYEVLKLSEDPLLATREFYGHLR
CCCCCHHHHHHHHHHHHCCCCHHHHCEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHH
DVAARGKDCILFYREAHQTGERWESLFDRLNKAASLIV
HHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]