| Definition | Bdellovibrio bacteriovorus HD100, complete genome. |
|---|---|
| Accession | NC_005363 |
| Length | 3,782,950 |
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The map label for this gene is fabG [H]
Identifier: 42521904
GI number: 42521904
Start: 267462
End: 268211
Strand: Direct
Name: fabG [H]
Synonym: Bd0281
Alternate gene names: 42521904
Gene position: 267462-268211 (Clockwise)
Preceding gene: 42521898
Following gene: 42521905
Centisome position: 7.07
GC content: 48.13
Gene sequence:
>750_bases ATGACAAATATTAATTTCGATTTCAAAAACAAAAATGCCATCGTGACCGGCGGAGCTTCCGGTATCGGTTTTCAAATCAC CAAAAGCTTTTTGGAAGCCGGTGGAAATGTTTCCATCTGGGATTATTCTGAAGCAGCTTTGCAAACGGCGAAATCTGAAT TTGCAAAGTACGGATCGCAGATTCACATCGCGCAAGTCGATGTGGGCAATCGTGACTCGGTAGCAAAAGCCGCGGCGTCC CTGCCGTGGACTGTGGATATTCTTGTGAACAACGCAGGTATCACCCGCGATAAGTCTTTTGCAAAAATGTCACCCGAGGA CTGGGATGCCGTCATCAGTACCAATCTGACAGGTTTGTTCAACGTCACGAAATCTGTTTTGGAAAAATTCAATCCAAACT CCAACAGCAAACGCATCATCAATATCGCGTCTGTTGTGGCGCTTTATGGAAACTTCGGTCAGACCAATTACGTGGCGGCA AAAGCCGGCGTGATCGGAATGTCCAAGACATGGGCGAAAGAACTGGGTCGCAAAGGCTTCACCTCCAATGCAATTGCTCC GGGCTTTATTGCAACAGCAATGACCAAGGCGATGCCTGCTGAAGTGCTGGATGGCATGAAAGCAAAAGTTCCAGTGGCAT GTTTGGGGGAAGTGGACGACATCGCCAATACATGTCTGTTCCTGTCCAGCGAGCAAGCGGGTTATATCAACGGCGCTGTG ATCAGCGTTGATGGTGGTTTGGTTCTATAA
Upstream 100 bases:
>100_bases TTTGGCAAGAAAAGAAATTTAGAGCATTCACTCTATACTCCGAGCGAAAAAGTGCTTTTTCCTTTGACGGACCGGGGGCC TGTCGGGGTACTTCAAGTGC
Downstream 100 bases:
>100_bases ATGATCTGACAACTTTTTTATAAGGAGTGACTTCGATGAGATTTCTGTTCTTGGCTTTGAGTGTCTTGGTATCAGGTTTC TTTGTGTCCTTGGAATCTTT
Product: 3-oxoacyl-(acyl carrier protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MTNINFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQIHIAQVDVGNRDSVAKAAAS LPWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLFNVTKSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAA KAGVIGMSKTWAKELGRKGFTSNAIAPGFIATAMTKAMPAEVLDGMKAKVPVACLGEVDDIANTCLFLSSEQAGYINGAV ISVDGGLVL
Sequences:
>Translated_249_residues MTNINFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQIHIAQVDVGNRDSVAKAAAS LPWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLFNVTKSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAA KAGVIGMSKTWAKELGRKGFTSNAIAPGFIATAMTKAMPAEVLDGMKAKVPVACLGEVDDIANTCLFLSSEQAGYINGAV ISVDGGLVL >Mature_248_residues TNINFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQIHIAQVDVGNRDSVAKAAASL PWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLFNVTKSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAAK AGVIGMSKTWAKELGRKGFTSNAIAPGFIATAMTKAMPAEVLDGMKAKVPVACLGEVDDIANTCLFLSSEQAGYINGAVI SVDGGLVL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=39.1634980988593, Blast_Score=174, Evalue=7e-44, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=33.6065573770492, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI4504505, Length=251, Percent_Identity=31.0756972111554, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=30.4, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=31.25, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=30.4878048780488, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI83715985, Length=251, Percent_Identity=29.4820717131474, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=26.1410788381743, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=26.1061946902655, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=26.6409266409266, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=26.4550264550265, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI31542939, Length=249, Percent_Identity=28.9156626506024, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI31543615, Length=213, Percent_Identity=30.0469483568075, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=39.7540983606557, Blast_Score=172, Evalue=1e-44, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.2834645669291, Blast_Score=127, Evalue=1e-30, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=33.201581027668, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.718875502008, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=30.7086614173228, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=31.1203319502075, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=29.5719844357977, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=36.4640883977901, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=26.2295081967213, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.0700389105058, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=3e-12, Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=44.2148760330579, Blast_Score=180, Evalue=7e-46, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=40.1639344262295, Blast_Score=172, Evalue=1e-43, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.1632653061224, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=31.3084112149533, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=29.7619047619048, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=29.1187739463602, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.1960784313725, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17564282, Length=243, Percent_Identity=28.3950617283951, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=29.3172690763052, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=26, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=27.9693486590038, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI193203117, Length=206, Percent_Identity=29.126213592233, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=27.9527559055118, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=26.7657992565056, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.8199233716475, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=25.2830188679245, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=23.5772357723577, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=25.5639097744361, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=24.7148288973384, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=213, Percent_Identity=31.4553990610329, Blast_Score=100, Evalue=2e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=32.5301204819277, Blast_Score=96, Evalue=5e-21, Organism=Saccharomyces cerevisiae, GI6323882, Length=238, Percent_Identity=26.890756302521, Blast_Score=72, Evalue=6e-14, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=38.2113821138211, Blast_Score=141, Evalue=4e-34, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=32.7868852459016, Blast_Score=100, Evalue=6e-22, Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=33.0739299610895, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.7269076305221, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=29.6747967479675, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=32.8358208955224, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI221331218, Length=194, Percent_Identity=34.020618556701, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=32.6732673267327, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI221331216, Length=195, Percent_Identity=33.8461538461538, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=29.0196078431373, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24581726, Length=210, Percent_Identity=25.2380952380952, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=27.843137254902, Blast_Score=67, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26244; Mature: 26113
Theoretical pI: Translated: 8.18; Mature: 8.18
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNINFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQ CCCCCEEECCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCE IHIAQVDVGNRDSVAKAAASLPWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLF EEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCHHCCCCCHHHHHHHCCCHHHH NVTKSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAAKAGVIGMSKTWAKELGRKGF HHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCCEEEECCCEECCCHHHHHHHCCCCC TSNAIAPGFIATAMTKAMPAEVLDGMKAKVPVACLGEVDDIANTCLFLSSEQAGYINGAV CCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCEEECCCHHHHHHHEEEEECCCCCEECCEE ISVDGGLVL EEECCCEEC >Mature Secondary Structure TNINFDFKNKNAIVTGGASGIGFQITKSFLEAGGNVSIWDYSEAALQTAKSEFAKYGSQ CCCCEEECCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCE IHIAQVDVGNRDSVAKAAASLPWTVDILVNNAGITRDKSFAKMSPEDWDAVISTNLTGLF EEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCHHCCCCCHHHHHHHCCCHHHH NVTKSVLEKFNPNSNSKRIINIASVVALYGNFGQTNYVAAKAGVIGMSKTWAKELGRKGF HHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCCCEEEECCCEECCCHHHHHHHCCCCC TSNAIAPGFIATAMTKAMPAEVLDGMKAKVPVACLGEVDDIANTCLFLSSEQAGYINGAV CCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCEEECCCHHHHHHHEEEEECCCCCEECCEE ISVDGGLVL EEECCCEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]