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The map label for this gene is mreB [H]

Identifier: 42521840

GI number: 42521840

Start: 201075

End: 202166

Strand: Direct

Name: mreB [H]

Synonym: Bd0211

Alternate gene names: 42521840

Gene position: 201075-202166 (Clockwise)

Preceding gene: 42521839

Following gene: 42521841

Centisome position: 5.32

GC content: 49.54

Gene sequence:

>1092_bases
TTGAACTGTTTAAAGCCCGATGAATATTACACTGAAGTGAGATTCAGCATGAGTTTTTTTGACAAAGTTCAAGATTATTT
TTCTAACGACATCGCCATTGACCTTGGCACCGCCAACACACTTGTTTACGTAAAAGGCCGCGGAATCATCCTTGATGAAC
CTTCCGTGGTTGCGGTCCAAAAGAATTATCGTGGGATGCAAAACCGCGTTCTTGCCGTAGGTAAAGAAGCCAAAGACATG
TTGGGACGTACACCTGGCAGCATCGTGGCGATCCGCCCGATCAAAGATGGTGTTATCGCTGACTTCGAAGTCACCCAGTC
CATGCTGAAGTACTTCATCGGCAAATCCCTTGGCGAGAAAAAATCCTTCATCCGTCCTCGTATCATCATCTGCGTTCCTT
ACGGAATCACTCAGGTTGAAAAACGTGCGGTGAAAGAGGCGGCTCAATCCGCAGGGGCTCGTGAGGTTTATCTGATCGAG
GAACCAATGGCAGCGGCGATCGGTGCCGGCCTTCCGATCACTGAACCATCCGGCAACATGGTTGTCGACATGGGCGGTGG
TACTACGGGTGTGGCGGTGATTTCTTTGGGTGGTATTGTTTACTGCAAATCCATCAAAGTTGCCGGTGACAAGTTTGACG
AGGCGATCGTGAACTATGTTCGTCGTCAGTTCAACCTTCTGATCGGTGAAAGAACCGCAGAAAACATCAAAATCCAAATC
GGTAACGCTTATCCGTTTGAAGAAGAAAAATCCATGGAGATCAAAGGCCGTGACCTTGTGGCCGGTGCTCCAAAAACCAT
CGAAATCACTTCTTCTCAAGTGAACGATGCTTTGATGGATCCTTTGTCTGAAGTGGTGGATGCAGTTCGTACCGCTCTGG
AAAAAACTCCACCGGAACTGGCTTCTGATATCGTGGACAACGGGATCGTTCTGACGGGCGGGGGCGCTTTGCTGGCGAAC
CTGGACGTGCTTCTGAGAGAAAGAACTGGACTGCCGGTTTCTATCGCGGAAGACCCACTTTCCTGCGTGGTGATGGGTTC
CGGTAAAGTTCTCGACCAGCTTGACCTTCTCAGACAGCTTACAGTCGATTAG

Upstream 100 bases:

>100_bases
GACGGGCACCGACCTTACGATCCAGTGTGCACCTGCGTCAAAATAAACTCAAAAAAGGCCTAAATATCAGTATTGACTCC
GGTTTTTATAGAACCTAGAC

Downstream 100 bases:

>100_bases
TATAGTAAGGGCATCCACAAACGGATGCCCTCGAACGCACGAATGGACTTAAAGGTGCTATGACCGAAGCTGACGTACAA
TCTATCGCTTTGTTTTTCTA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNCLKPDEYYTEVRFSMSFFDKVQDYFSNDIAIDLGTANTLVYVKGRGIILDEPSVVAVQKNYRGMQNRVLAVGKEAKDM
LGRTPGSIVAIRPIKDGVIADFEVTQSMLKYFIGKSLGEKKSFIRPRIIICVPYGITQVEKRAVKEAAQSAGAREVYLIE
EPMAAAIGAGLPITEPSGNMVVDMGGGTTGVAVISLGGIVYCKSIKVAGDKFDEAIVNYVRRQFNLLIGERTAENIKIQI
GNAYPFEEEKSMEIKGRDLVAGAPKTIEITSSQVNDALMDPLSEVVDAVRTALEKTPPELASDIVDNGIVLTGGGALLAN
LDVLLRERTGLPVSIAEDPLSCVVMGSGKVLDQLDLLRQLTVD

Sequences:

>Translated_363_residues
MNCLKPDEYYTEVRFSMSFFDKVQDYFSNDIAIDLGTANTLVYVKGRGIILDEPSVVAVQKNYRGMQNRVLAVGKEAKDM
LGRTPGSIVAIRPIKDGVIADFEVTQSMLKYFIGKSLGEKKSFIRPRIIICVPYGITQVEKRAVKEAAQSAGAREVYLIE
EPMAAAIGAGLPITEPSGNMVVDMGGGTTGVAVISLGGIVYCKSIKVAGDKFDEAIVNYVRRQFNLLIGERTAENIKIQI
GNAYPFEEEKSMEIKGRDLVAGAPKTIEITSSQVNDALMDPLSEVVDAVRTALEKTPPELASDIVDNGIVLTGGGALLAN
LDVLLRERTGLPVSIAEDPLSCVVMGSGKVLDQLDLLRQLTVD
>Mature_363_residues
MNCLKPDEYYTEVRFSMSFFDKVQDYFSNDIAIDLGTANTLVYVKGRGIILDEPSVVAVQKNYRGMQNRVLAVGKEAKDM
LGRTPGSIVAIRPIKDGVIADFEVTQSMLKYFIGKSLGEKKSFIRPRIIICVPYGITQVEKRAVKEAAQSAGAREVYLIE
EPMAAAIGAGLPITEPSGNMVVDMGGGTTGVAVISLGGIVYCKSIKVAGDKFDEAIVNYVRRQFNLLIGERTAENIKIQI
GNAYPFEEEKSMEIKGRDLVAGAPKTIEITSSQVNDALMDPLSEVVDAVRTALEKTPPELASDIVDNGIVLTGGGALLAN
LDVLLRERTGLPVSIAEDPLSCVVMGSGKVLDQLDLLRQLTVD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=340, Percent_Identity=60, Blast_Score=423, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17507981, Length=379, Percent_Identity=26.3852242744063, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320805, Length=256, Percent_Identity=28.515625, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 39253; Mature: 39253

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCLKPDEYYTEVRFSMSFFDKVQDYFSNDIAIDLGTANTLVYVKGRGIILDEPSVVAVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEECCCCEEEEE
KNYRGMQNRVLAVGKEAKDMLGRTPGSIVAIRPIKDGVIADFEVTQSMLKYFIGKSLGEK
CCCCCHHHHEEEECCHHHHHHCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHCCCCCCH
KSFIRPRIIICVPYGITQVEKRAVKEAAQSAGAREVYLIEEPMAAAIGAGLPITEPSGNM
HHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCE
VVDMGGGTTGVAVISLGGIVYCKSIKVAGDKFDEAIVNYVRRQFNLLIGERTAENIKIQI
EEECCCCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
GNAYPFEEEKSMEIKGRDLVAGAPKTIEITSSQVNDALMDPLSEVVDAVRTALEKTPPEL
CCCCCCCCCCCCEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ASDIVDNGIVLTGGGALLANLDVLLRERTGLPVSIAEDPLSCVVMGSGKVLDQLDLLRQL
HHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHH
TVD
CCC
>Mature Secondary Structure
MNCLKPDEYYTEVRFSMSFFDKVQDYFSNDIAIDLGTANTLVYVKGRGIILDEPSVVAVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEECCCCEEEEE
KNYRGMQNRVLAVGKEAKDMLGRTPGSIVAIRPIKDGVIADFEVTQSMLKYFIGKSLGEK
CCCCCHHHHEEEECCHHHHHHCCCCCCEEEEEECCCCCEECHHHHHHHHHHHHCCCCCCH
KSFIRPRIIICVPYGITQVEKRAVKEAAQSAGAREVYLIEEPMAAAIGAGLPITEPSGNM
HHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCE
VVDMGGGTTGVAVISLGGIVYCKSIKVAGDKFDEAIVNYVRRQFNLLIGERTAENIKIQI
EEECCCCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
GNAYPFEEEKSMEIKGRDLVAGAPKTIEITSSQVNDALMDPLSEVVDAVRTALEKTPPEL
CCCCCCCCCCCCEECCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ASDIVDNGIVLTGGGALLANLDVLLRERTGLPVSIAEDPLSCVVMGSGKVLDQLDLLRQL
HHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHH
TVD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]