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The map label for this gene is galE [H]

Identifier: 41410129

GI number: 41410129

Start: 4491995

End: 4492465

Strand: Direct

Name: galE [H]

Synonym: MAP4031

Alternate gene names: 41410129

Gene position: 4491995-4492465 (Clockwise)

Preceding gene: 41410128

Following gene: 41410130

Centisome position: 93.01

GC content: 77.07

Gene sequence:

>471_bases
ATGAGGGTGCTGGTGACGGGGGCGGCCGGGTTCATCGGCTCGCGGGTGGCCGCCGCGCTGCGGGCGGCGGGCCACGACGT
CGTCGCCGTCGACGCGTTACTGGCCGCCGCGCACGGACCGAACCCGCTGCCGCCCAACGGGTGTCACCGCGTCGACGTGC
GCGACGCCGACGCGCTGGCCCCGCTGCTGGCCGGGGTGGACGTGGTGTGCCACCAGGCGGCGATGGTGGGGGCGGGGGTC
GACGCCGCCGACGCCCCGGCCTACGGCGGCCACAACGACCTGGCCACCACGGTGCTGCTGGCCCAGATGTTCGCCGCCGG
GGTGCGCCGGCTGGTGCTGGCCTCGTCGATGGTCGTGTACGGGCAGGGCGGTTACCGCTGCGAGCGGCACGGGCCGGTGC
ACCCCGCTGCCGCGGCGGCGTGCGGACCTGGACGCCGGGGTCTTCGAGCACCGGTGCCCGATCGGCGGTGA

Upstream 100 bases:

>100_bases
TCAAGAAGCTGGTGCGCGACGCCATCGGCCGGGTCGCCGCCGAGCGCAGCTGTACGCAGTGCTCACCGCACACCGGGGTG
AGCCTGCCGATCGAGCTGCC

Downstream 100 bases:

>100_bases
GGAGCTGCGCTGGCAGCTGGTCGACGAGGACGCCTGCCTGCGGCCTCGCAGCCTGTACGCCGCCAGCAAGACCGCCCAGG
AGCATTACGCGCTGGCCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALAPLLAGVDVVCHQAAMVGAGV
DAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVYGQGGYRCERHGPVHPAAAAACGPGRRGLRAPVPDRR

Sequences:

>Translated_156_residues
MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALAPLLAGVDVVCHQAAMVGAGV
DAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVYGQGGYRCERHGPVHPAAAAACGPGRRGLRAPVPDRR
>Mature_156_residues
MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALAPLLAGVDVVCHQAAMVGAGV
DAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVYGQGGYRCERHGPVHPAAAAACGPGRRGLRAPVPDRR

Specific function: Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=129, Percent_Identity=32.5581395348837, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 15706; Mature: 15706

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALA
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
PLLAGVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
GQGGYRCERHGPVHPAAAAACGPGRRGLRAPVPDRR
CCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLVTGAAGFIGSRVAAALRAAGHDVVAVDALLAAAHGPNPLPPNGCHRVDVRDADALA
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
PLLAGVDVVCHQAAMVGAGVDAADAPAYGGHNDLATTVLLAQMFAAGVRRLVLASSMVVY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
GQGGYRCERHGPVHPAAAAACGPGRRGLRAPVPDRR
CCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8355614 [H]