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The map label for this gene is senX3

Identifier: 41410080

GI number: 41410080

Start: 4440671

End: 4441900

Strand: Direct

Name: senX3

Synonym: MAP3982

Alternate gene names: 41410080

Gene position: 4440671-4441900 (Clockwise)

Preceding gene: 41410079

Following gene: 41410081

Centisome position: 91.94

GC content: 69.59

Gene sequence:

>1230_bases
GTGACTGTGTTCTCGGCACTGTTGCTGGCCGGGGTCTTGTCCGTGCTGGCACTGGCCGCAGGTGTGGCGGTCGGGACCCG
GTTGTCCCCGCGGGCGGCGCAGCGCCGCCAGCGAATCAGCACCGAATGGACCGGGATCACCGTCGCGCAGATGCTGGAAC
GCATCGTGGCGCTGATGCCGCTGGGCGCGGCGGTGGTGGACGCCCACCGCGACGTCGTCTACCTCAACGACCGGGCCAAG
GAGCTGGGCCTGGTGCGCGACCGCCAGCTCGATGACCAGGCCTGGGAGGCCGCGCAGCAGGCGCTGACCGGTGTCGACGT
GGAATTCGACCTGCGGCCGGCGAAACGGTCCGGGGGCCGGGCCGGCCTGTCGGTGCACGGGCAGGCGCGGTTGCTCAGCG
AGGAAGACCGCCGGTTCGCCGTGGTGTTCGCCCACGACCAGTCCGACTATGCCCGGATGGAGGCGACCCGGCGCGACTTC
GTGGCCAACGTCAGCCACGAGCTCAAGACGCCGGTGGGGGCCATGGCGCTGCTCGCCGAGGCGCTGCTGGCGTCGGCCGA
CGACTCCGAGACCGTGCGCCGGTTCGCCGAGAAGGTGCTGGTCGAGGCCAACCGGCTGGGCGACATGGTTGCCGAGCTGA
TCGAGCTGTCCCGGCTGCAGGGCGCCGAGCGGTTGACCAACGTCACCGAGGTCAACGTGGATAGTGTTGTGAACGAAGCG
ATTTCGCGCCACAAGGTGGCGGCCGACAACGCCAACATCGAGGTCCGGACCGACGCCCCCAGCGGTTTGCGGGTGCTGGG
CGACGAGACGCTGTTGGTCACGGCGTTGGCGAACCTGGTGTCCAATGCCATCGCCTATTCGCCGCCGGGCTCGCCGGTGT
CGATCAGCCGTCGCCGCCGCGGCGACAACATCGAGATCGCCGTCACCGACCGCGGCATCGGCATCGCGCTGGAGGATCAG
GAGCGGGTTTTCGAGCGGTTCTTCCGGGGGGACAAGGCGCGCTCACGCGCCACCGGCGGCAGCGGCCTGGGCCTGGCCAT
CGTCAAGCACGTCGCGGCCAATCACAACGGCACCATCGGGGTGTGGAGCAAGCCGGGCACCGGATCGACATTCACCCTGT
CCATTCCGGCGGCCGTGGCGTCGCATCGGGGCGACGGCGAATCCGAGCAGCCGCAGGGTCGTGACGTGCGGCCCAACCGT
TCCCAACGAGAGGAAGAACTAAGCCGATGA

Upstream 100 bases:

>100_bases
GTGAACGGAAGCAGAACACCTGTTACGCAAGGTGTGACTTGTCCGATTTTGGCCTCGTTCCGCTAGGGCAGCGTTCAGGA
AGATTTGTAGGATTTGCTAT

Downstream 100 bases:

>100_bases
CTCGCGCGTATGACGATGCAGAGCGTAGCGATGAGGAGGAATCGCGCCGATGACCCGCGCGTATGACGATGCAGAGCGTA
GCGATGAGGAGGAATCGCGC

Product: SenX3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMPLGAAVVDAHRDVVYLNDRAK
ELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSGGRAGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDF
VANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNEA
ISRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRGDNIEIAVTDRGIGIALEDQ
ERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGVWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNR
SQREEELSR

Sequences:

>Translated_409_residues
MTVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMPLGAAVVDAHRDVVYLNDRAK
ELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSGGRAGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDF
VANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNEA
ISRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRGDNIEIAVTDRGIGIALEDQ
ERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGVWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNR
SQREEELSR
>Mature_408_residues
TVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMPLGAAVVDAHRDVVYLNDRAKE
LGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSGGRAGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFV
ANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNEAI
SRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRGDNIEIAVTDRGIGIALEDQE
RVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIGVWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNRS
QREEELSR

Specific function: Probably forms part of a two-component regulatory system senX3/regX3. Phosphorylates regX3 (Probable) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=265, Percent_Identity=33.2075471698113, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=29.2237442922374, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=30.0884955752212, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=27.5720164609054, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=29.1845493562232, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=273, Percent_Identity=27.4725274725275, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693157, Length=405, Percent_Identity=25.9259259259259, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=30.2127659574468, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=25.1028806584362, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=27.0386266094421, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787894, Length=242, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=28.5087719298246, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=26.890756302521, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=200, Percent_Identity=30, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=204, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788279, Length=231, Percent_Identity=24.6753246753247, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790551, Length=222, Percent_Identity=29.2792792792793, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=27.1317829457364, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=27.734375, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=106, Percent_Identity=37.7358490566038, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44125; Mature: 43994

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMP
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
LGAAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSGGR
CCHHHHHCCCCEEEECCCHHHHCCHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCC
AGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAE
CCEEECCCHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNEA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
ISRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRR
HHHHEEECCCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHCC
GDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIG
CCCEEEEEECCCCEEEECCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCCCEEE
VWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNRSQREEELSR
EECCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
TVFSALLLAGVLSVLALAAGVAVGTRLSPRAAQRRQRISTEWTGITVAQMLERIVALMP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
LGAAVVDAHRDVVYLNDRAKELGLVRDRQLDDQAWEAAQQALTGVDVEFDLRPAKRSGGR
CCHHHHHCCCCEEEECCCHHHHCCHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCC
AGLSVHGQARLLSEEDRRFAVVFAHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAE
CCEEECCCHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLTNVTEVNVDSVVNEA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
ISRHKVAADNANIEVRTDAPSGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRR
HHHHEEECCCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHCC
GDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGTIG
CCCEEEEEECCCCEEEECCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCCCEEE
VWSKPGTGSTFTLSIPAAVASHRGDGESEQPQGRDVRPNRSQREEELSR
EECCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9426136; 12788972 [H]