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The map label for this gene is gpmA

Identifier: 41410079

GI number: 41410079

Start: 4439757

End: 4440506

Strand: Direct

Name: gpmA

Synonym: MAP3981

Alternate gene names: 41410079

Gene position: 4439757-4440506 (Clockwise)

Preceding gene: 41410078

Following gene: 41410080

Centisome position: 91.92

GC content: 71.73

Gene sequence:

>750_bases
ATGGGTGAGACTGCCACGCTGGTACTGCTGCGCCACGGCGAAAGCGAATGGAACTCGCTGAACCTGTTCACCGGTTGGGT
GGACGTCGGGCTGACCGACAAGGGCCGCGCCGAGGCGGTGCGCAGCGGCGAGCTGCTGGCCGAGCAGGGCCTGCTGCCCG
ACGCGCTCTACACGTCGCTGCTGCGCCGCGCGATCACCACCGCGCATCTGGCCCTGGACGCCGCGGACCGGCTGTGGATC
CCGGTGCGGCGCAGCTGGCGGCTCAACGAACGCCACTACGGGGCGCTGCAGGGCCTGGACAAGGCCGAGACGAAGGCGCG
CTACGGCGAGGAGCAGTTCATGGCCTGGCGACGCAGCTATGACACGCCGCCGCCGCCGATCGAGCGGGGCAGCACCTACA
GCCAGGACGCCGATCCGCGCTACGCCGACATCGGCGGCGGGCCGCTGACCGAGTGCCTGGCCGACGTGGTCGTCCGGTTC
CTGCCGTACTTCACCGACGTCATCGTCCCGGACCTGCGCAGCGGCAAGACGGTGCTGATCGTCGCGCACGGCAACTCGCT
GCGCGCCCTGGTCAAGCACCTCGATCAGATGTCCGACGACGACGTCGTGGGGCTGAACATCCCGACCGGCATCCCGCTGC
GCTACGACTTGGACGCCCGGCTGCGGCCGCTGGTTCCCGGCGGCACCTACCTCGACCCCGAGGCGGCCGCCGCCGGCGCC
GCCGCGGTTGCCAGCCAGGGGCGCGGCTGA

Upstream 100 bases:

>100_bases
GAAGAACCTGCAGGCCTTTGCTCATCTGATCGACGACGACGAGGGTTAGCCCGGGGCCACGCCCGGCAGCGCTTTTCGGG
TGCGTGAGAGACTAACCGGC

Downstream 100 bases:

>100_bases
GGCGTCGAACCCCGCCGGGAGGCTGCCCAGGGGGGCGCCGAAAGCCCCATTTGCCAAACAGCACGTGAACGGAAGCAGAA
CACCTGTTACGCAAGGTGTG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSLLRRAITTAHLALDAADRLWI
PVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRF
LPYFTDVIVPDLRSGKTVLIVAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGA
AAVASQGRG

Sequences:

>Translated_249_residues
MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSLLRRAITTAHLALDAADRLWI
PVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRF
LPYFTDVIVPDLRSGKTVLIVAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGA
AAVASQGRG
>Mature_248_residues
GETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSLLRRAITTAHLALDAADRLWIP
VRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRFL
PYFTDVIVPDLRSGKTVLIVAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGAA
AVASQGRG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=48.4, Blast_Score=247, Evalue=6e-66,
Organism=Homo sapiens, GI4505753, Length=247, Percent_Identity=48.9878542510121, Blast_Score=229, Evalue=1e-60,
Organism=Homo sapiens, GI4502445, Length=249, Percent_Identity=44.578313253012, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI40353764, Length=249, Percent_Identity=44.578313253012, Blast_Score=218, Evalue=4e-57,
Organism=Homo sapiens, GI71274132, Length=247, Percent_Identity=46.5587044534413, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=50.625, Blast_Score=144, Evalue=9e-35,
Organism=Escherichia coli, GI1786970, Length=220, Percent_Identity=52.7272727272727, Blast_Score=244, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=64.7540983606557, Blast_Score=296, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=33.445945945946, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324516, Length=295, Percent_Identity=33.2203389830508, Blast_Score=154, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24646216, Length=248, Percent_Identity=47.9838709677419, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI85725270, Length=253, Percent_Identity=48.2213438735178, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI85725272, Length=253, Percent_Identity=48.2213438735178, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24650981, Length=253, Percent_Identity=48.2213438735178, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28571817, Length=253, Percent_Identity=38.3399209486166, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28571815, Length=253, Percent_Identity=38.3399209486166, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24648979, Length=253, Percent_Identity=38.3399209486166, Blast_Score=160, Evalue=7e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27231; Mature: 27100

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSL
CCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHCHHHHHCCCCCHHHHHHH
LRRAITTAHLALDAADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHCC
DTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRFLPYFTDVIVPDLRSGKTVLI
CCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGA
EECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCEECHHHHHHHH
AAVASQGRG
HHHHCCCCC
>Mature Secondary Structure 
GETATLVLLRHGESEWNSLNLFTGWVDVGLTDKGRAEAVRSGELLAEQGLLPDALYTSL
CCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHCHHHHHCCCCCHHHHHHH
LRRAITTAHLALDAADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSY
HHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHCC
DTPPPPIERGSTYSQDADPRYADIGGGPLTECLADVVVRFLPYFTDVIVPDLRSGKTVLI
CCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VAHGNSLRALVKHLDQMSDDDVVGLNIPTGIPLRYDLDARLRPLVPGGTYLDPEAAAAGA
EECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCEECHHHHHHHH
AAVASQGRG
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA