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The map label for this gene is hbhA [H]

Identifier: 41410066

GI number: 41410066

Start: 4428497

End: 4429084

Strand: Direct

Name: hbhA [H]

Synonym: MAP3968

Alternate gene names: 41410066

Gene position: 4428497-4429084 (Clockwise)

Preceding gene: 41410065

Following gene: 41410067

Centisome position: 91.69

GC content: 71.77

Gene sequence:

>588_bases
ATGAAAGGAACAACCATGGCGGAAAACCCGAACATCGACGACTTGCGAGCCCCGCTGCTCGCGGCCCTGGGCGCGGCCGA
CCTGGCCCTGGCCACGGTCAACGACCTGATCGCCAACCTGCGCGAGCGGGCCGAGGAGACCCGCGCCGAGACCCGCACCC
GGGTCGAGGAGCGCCGCGCCCGGCTGACCAAGTTCCAGGAGGACCTGCCCGAGCAGTTCACCGAGCTGCGCGACAAGTTC
ACCACCGAGGAGCTGCGCAAGGCGGCCGAGGGCTACCTGGAGGCGGCGACCAACCGGTACAACGAGCTGGTCGAGCGCGG
CGAGGCGGCCCTGCAGCGGCTGCGCAGCCAGACCGCCTTCGAGGACGCCTCCGCGCGCGCCGAGGGCTACGTGGACCAGG
CCGTCGAGCTGACCCAGGAGGCGCTGGGCACCGTCGCGTCGCAGACCCGCGCGGTCGGTGAGCGCGCCGCCAAGCTGGTG
GGCATCGAGCTGCCGGGCAAGGCCGAGGCCGCCGGCAAGAAGGCCCAGAAGGCCATCGCCAAGGCCCCCGCCAAGAAGGC
GCCGGCCAAGAAGGTCACCCAGAAGTAG

Upstream 100 bases:

>100_bases
CATGACGAACGACCGACGCTCCGCGCGGCCCCAGTTGCGAAGGAGACGTTTGCACCTAATTTCCCGACCAGACACCTGAC
AAACACACAGAGCAGAAACC

Downstream 100 bases:

>100_bases
CACCGCAGTTCCCACGACGCTCGACTCCGAGTTGCCTTCGGGTGACTCGGAGTCGACGTTGCGGACGCCGCCCGCCTACG
CTTGAGGCGTGAACCACCTC

Product: hypothetical protein

Products: NA

Alternate protein names: Adhesin [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKGTTMAENPNIDDLRAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRARLTKFQEDLPEQFTELRDKF
TTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLV
GIELPGKAEAAGKKAQKAIAKAPAKKAPAKKVTQK

Sequences:

>Translated_195_residues
MKGTTMAENPNIDDLRAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRARLTKFQEDLPEQFTELRDKF
TTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLV
GIELPGKAEAAGKKAQKAIAKAPAKKAPAKKVTQK
>Mature_195_residues
MKGTTMAENPNIDDLRAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRARLTKFQEDLPEQFTELRDKF
TTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLV
GIELPGKAEAAGKKAQKAIAKAPAKKAPAKKVTQK

Specific function: Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells; binds heparin, dextran sulfate, fucoidan and chondroitin sulfate. Promotes hemagglutination of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae hbhA [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020340
- ProDom:   PD082580 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21291; Mature: 21291

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTTMAENPNIDDLRAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTKFQEDLPEQFTELRDKFTTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPGKAEAAGKKAQKAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KAPAKKAPAKKVTQK
HCCHHCCCHHHHCCC
>Mature Secondary Structure
MKGTTMAENPNIDDLRAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLTKFQEDLPEQFTELRDKFTTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELPGKAEAAGKKAQKAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KAPAKKAPAKKVTQK
HCCHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972; 11449276 [H]