Click here to switch to the map view.

The map label for this gene is pepA

Identifier: 41409625

GI number: 41409625

Start: 3929882

End: 3930967

Strand: Direct

Name: pepA

Synonym: MAP3527

Alternate gene names: 41409625

Gene position: 3929882-3930967 (Clockwise)

Preceding gene: 41409622

Following gene: 41409626

Centisome position: 81.37

GC content: 72.1

Gene sequence:

>1086_bases
ATGAGCAAATCGCACCACCACCGCTCGGTCTGGTGGTCATGGTTGGTCGGTGTGCTGACCGTGGTCGGGCTGGGCCTCGG
GCTGGGGTCCGGCGTGGGGCTGGCGCCGGCGTCCGCGGCACCGTCGGGCCTGGCGCTGGACCGGTTCGCCGATCGCCCCC
TGGCGCCGATCGACCCGTCGGCCATGGTCGGTCAGGTGGGGCCGCAAGTGGTCAACATCGACACCAAGTTCGGCTACAAC
AACGCGGTGGGCGCCGGTACCGGCATCGTGATCGACCCGAACGGCGTGGTGCTCACCAACAACCACGTCATCTCGGGCGC
CACCGAAATCAGCGCGTTCGACGTCGGCAACGGGCAGACCTACGCCGTCGACGTGGTCGGCTATGACCGCACCCAGGACA
TCGCCGTGCTGCAGCTGCGCGGCGCGGCCGGCCTGCCCACCGCCACCATCGGCGGCGAGGCCACGGTGGGCGAGCCCATC
GTCGCGCTTGGCAACGTCGGCGGCCAGGGCGGCACCCCCAACGCGGTGGCCGGCAAGGTCGTCGCGCTCAACCAGAGCGT
CTCGGCGACCGACACGCTGACCGGCGCGCAGGAGAACCTCGGCGGCCTGATCCAGGCCGACGCGCCGATCAAGCCGGGCG
ACTCCGGTGGCCCGATGGTGAACAGCGCCGGGCAGGTGATCGGCGTGGACACCGCCGCCACCGACAGCTACAAGATGTCC
GGCGGGCAGGGCTTCGCCATCCCGATCGGCCGCGCCATGGCCGTCGCCAACCAGATCCGCTCCGGCGCCGGCTCCAACAC
CGTGCACATCGGGCCCACCGCATTCCTCGGGCTGGGCGTGACGGACAACAACGGCAACGGCGCGCGGGTGCAGCGGGTGG
TCAACACCGGCCCGGCCGCGGCCGCGGGCATCGCGCCCGGCGACGTCATCACCGGCGTCGACACCGTCCCGATCAACGGG
GCGACGTCGATGACCGAGGTGCTCGTCCCGCACCACCCCGGTGACACCATCGCGGTGCACTTCCGGTCCGTCGACGGCGG
CGAGCGCACCGCGAACATCACCCTGGCGGAGGGGCCGCCGGCCTGA

Upstream 100 bases:

>100_bases
GCATAGCTACCTGCATTACGGTTATATACACAAAATTGTGCCGCCAGGATCCTCAGGCCGGGACAGTTTGGTGTTTACCG
CGACGCAGGAGGGTGACGGG

Downstream 100 bases:

>100_bases
CATCCGCGCCGGTGAGAGCGGGTCGGTGGCCAATTCGCTTGGCACCGGGCGTGATTCGTCGCGGCCGGGCGAGGGGGGTT
CCGAAACTCGCACTCAGGGT

Product: PepA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPSAMVGQVGPQVVNIDTKFGYN
NAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQTYAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPI
VALGNVGGQGGTPNAVAGKVVALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS
GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAAAAGIAPGDVITGVDTVPING
ATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPPA

Sequences:

>Translated_361_residues
MSKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPSAMVGQVGPQVVNIDTKFGYN
NAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQTYAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPI
VALGNVGGQGGTPNAVAGKVVALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS
GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAAAAGIAPGDVITGVDTVPING
ATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPPA
>Mature_360_residues
SKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPSAMVGQVGPQVVNIDTKFGYNN
AVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQTYAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPIV
ALGNVGGQGGTPNAVAGKVVALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMSG
GQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAAAAGIAPGDVITGVDTVPINGA
TSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPPA

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=297, Percent_Identity=26.5993265993266, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI24308541, Length=293, Percent_Identity=28.6689419795222, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4506141, Length=290, Percent_Identity=26.8965517241379, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI7019477, Length=289, Percent_Identity=29.757785467128, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789630, Length=370, Percent_Identity=29.1891891891892, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789629, Length=272, Percent_Identity=31.9852941176471, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786356, Length=242, Percent_Identity=33.4710743801653, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646839, Length=269, Percent_Identity=27.8810408921933, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35709; Mature: 35578

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPS
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
AMVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQT
HHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEECCEEECCCCEEEEEECCCCCE
YAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPIVALGNVGGQGGTPNAVAGKV
EEEEEEECCCCCCEEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCHHCCEE
VALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS
EEECCCCCCCHHCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEC
GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAA
CCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCCCCEEEEEECCCCCC
AAGIAPGDVITGVDTVPINGATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPP
CCCCCCCCEECCCCEECCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCC
A
C
>Mature Secondary Structure 
SKSHHHRSVWWSWLVGVLTVVGLGLGLGSGVGLAPASAAPSGLALDRFADRPLAPIDPS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
AMVGQVGPQVVNIDTKFGYNNAVGAGTGIVIDPNGVVLTNNHVISGATEISAFDVGNGQT
HHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEECCEEECCCCEEEEEECCCCCE
YAVDVVGYDRTQDIAVLQLRGAAGLPTATIGGEATVGEPIVALGNVGGQGGTPNAVAGKV
EEEEEEECCCCCCEEEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCHHCCEE
VALNQSVSATDTLTGAQENLGGLIQADAPIKPGDSGGPMVNSAGQVIGVDTAATDSYKMS
EEECCCCCCCHHCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEC
GGQGFAIPIGRAMAVANQIRSGAGSNTVHIGPTAFLGLGVTDNNGNGARVQRVVNTGPAA
CCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCCCCEEEEEECCCCCC
AAGIAPGDVITGVDTVPINGATSMTEVLVPHHPGDTIAVHFRSVDGGERTANITLAEGPP
CCCCCCCCEECCCCEECCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9829922 [H]