BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is fabG [H]

Identifier: 41409605

GI number: 41409605

Start: 3904021

End: 3904869

Strand: Direct

Name: fabG [H]

Synonym: MAP3507

Alternate gene names: 41409605

Gene position: 3904021-3904869 (Clockwise)

Preceding gene: 41409600

Following gene: 41409606

Centisome position: 80.83

GC content: 70.91

Gene sequence:

>849_bases
ATGGACGACGATCTCCTCAGGCTCGAGGGCCGCGTGGTGGTGGTGTCCGGCGCCGGTGGCGGCGGCATCGGCACCACCGT
CACGGCCATGGCCGCCCGGGCCGGGGCCACCGTGATCGCGGTGAGCCGGTCGAAGGAGAACCTCGACGAGCACATCGCCC
CGCTGGCCGCCCGGGGGCTGGCCGTCCTGCCCGTCGCCGCCGATGCCTCCACCGACGAGGGCATCGCCGCGGTGATCGAC
CAGGCGCGCCGGGCGGACGGGCGGCTGTACGGACTGGTCAACGTCGCCGGCGGTGCGGAACCGTCGACCTGGATGCCGTC
GACCCGGGTGTCGCGCACCGACTGGCGCAAGATCTTCGCCGATAACCTCGAAACGGCGTTCTTCATGAGCCAGGCCGTCG
CAGCCGAGCTCCTCGCACGGCGACTGCCCGGGTCGATCGTGTCGATCTCCTCGATCAGCGGCATGAACACCGCGCCGTTC
CACATCGCCTACGGGACGGCCAAATCCGCCATCGCGGCGATGACCCGCACCATGGCGCTGGAGCTGGCGCAGTCCGCGAT
CCGGGTGAACGCCGTGGCGCCCGGCGTCACCGAGACGGCCGCTTCCCGCACCTACGTCGCCGACGACCCGGATCGGGATC
GACGGGCGATCGCGATGGGCCGCCGCGGCCGGCCCGAGGAGCAGGCCGGCGCCATCCTGTTTCTGCTCTCCGAGCTGTCG
AGCTACGTCACCGGCCAGACGCTGCTCGTCGACGGCGGGCTGGACCTGCGATGGAGTCACCTCGGCGCCGACAACACGTC
GCTGTTCCTGCATGACGAATCCTTCCGCGCAACGATCAGGAGGATGTGA

Upstream 100 bases:

>100_bases
GTGTTCTCCACGGGACAGAATGCGATATTTTGTCCGGACAAAAATCGGGTGAACCTCGCCGCCGCCGGCCCGCCGGTGTC
CGGGCAGCAGAAAGCAGGTC

Downstream 100 bases:

>100_bases
TGACCGACGTTGCCAAGGACGCGAATTCCGCGGTGGCAGAAGAACTCTCCACGCCGATGACGATCGGGGTGGAGGCGTAC
ATCAGCGAGGACTATGCCCG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MDDDLLRLEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGLAVLPVAADASTDEGIAAVID
QARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAFFMSQAVAAELLARRLPGSIVSISSISGMNTAPF
HIAYGTAKSAIAAMTRTMALELAQSAIRVNAVAPGVTETAASRTYVADDPDRDRRAIAMGRRGRPEEQAGAILFLLSELS
SYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRATIRRM

Sequences:

>Translated_282_residues
MDDDLLRLEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGLAVLPVAADASTDEGIAAVID
QARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAFFMSQAVAAELLARRLPGSIVSISSISGMNTAPF
HIAYGTAKSAIAAMTRTMALELAQSAIRVNAVAPGVTETAASRTYVADDPDRDRRAIAMGRRGRPEEQAGAILFLLSELS
SYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRATIRRM
>Mature_282_residues
MDDDLLRLEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGLAVLPVAADASTDEGIAAVID
QARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFADNLETAFFMSQAVAAELLARRLPGSIVSISSISGMNTAPF
HIAYGTAKSAIAAMTRTMALELAQSAIRVNAVAPGVTETAASRTYVADDPDRDRRAIAMGRRGRPEEQAGAILFLLSELS
SYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRATIRRM

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.6612903225806, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=31.9230769230769, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=36.1111111111111, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=31.7647058823529, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=31.2, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI126723750, Length=234, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=32.2834645669291, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=29.6747967479675, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=27.3109243697479, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=32.1608040201005, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=34.1269841269841, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.852140077821, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=30.7392996108949, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=32.8301886792453, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.6274509803922, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788459, Length=170, Percent_Identity=37.0588235294118, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=30.3030303030303, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=31.5589353612167, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.8897637795276, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=184, Percent_Identity=32.0652173913043, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1786701, Length=202, Percent_Identity=29.2079207920792, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=32.319391634981, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=32.9588014981273, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=33.7349397590361, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=33.0612244897959, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.5555555555556, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=30.7692307692308, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=31.9852941176471, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=29.8507462686567, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=31.2267657992565, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=31.1023622047244, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.0861423220974, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=31.0756972111554, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=283, Percent_Identity=30.7420494699647, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=31.3432835820896, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=29.2592592592593, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=29.8507462686567, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=29.9625468164794, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=276, Percent_Identity=28.9855072463768, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.1992619926199, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=27.5092936802974, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=273, Percent_Identity=26.7399267399267, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=273, Percent_Identity=26.007326007326, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=217, Percent_Identity=26.7281105990783, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=155, Percent_Identity=33.5483870967742, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=283, Percent_Identity=26.8551236749117, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=32.4110671936759, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32.4, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24644337, Length=234, Percent_Identity=32.0512820512821, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=32.2709163346614, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=34.6303501945525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=32.3076923076923, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=30.952380952381, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=31.8897637795276, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29739; Mature: 29739

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDDLLRLEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGL
CCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCE
AVLPVAADASTDEGIAAVIDQARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFA
EEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
DNLETAFFMSQAVAAELLARRLPGSIVSISSISGMNTAPFHIAYGTAKSAIAAMTRTMAL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHH
ELAQSAIRVNAVAPGVTETAASRTYVADDPDRDRRAIAMGRRGRPEEQAGAILFLLSELS
HHHHHHHEEEECCCCCHHHHCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
SYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRATIRRM
HHHCCCEEEEECCCCEEEEECCCCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MDDDLLRLEGRVVVVSGAGGGGIGTTVTAMAARAGATVIAVSRSKENLDEHIAPLAARGL
CCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCE
AVLPVAADASTDEGIAAVIDQARRADGRLYGLVNVAGGAEPSTWMPSTRVSRTDWRKIFA
EEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
DNLETAFFMSQAVAAELLARRLPGSIVSISSISGMNTAPFHIAYGTAKSAIAAMTRTMAL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHH
ELAQSAIRVNAVAPGVTETAASRTYVADDPDRDRRAIAMGRRGRPEEQAGAILFLLSELS
HHHHHHHEEEECCCCCHHHHCCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHH
SYVTGQTLLVDGGLDLRWSHLGADNTSLFLHDESFRATIRRM
HHHCCCEEEEECCCCEEEEECCCCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]