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The map label for this gene is thcR [H]

Identifier: 41409328

GI number: 41409328

Start: 3583772

End: 3584848

Strand: Reverse

Name: thcR [H]

Synonym: MAP3230c

Alternate gene names: 41409328

Gene position: 3584848-3583772 (Counterclockwise)

Preceding gene: 41409329

Following gene: 41409327

Centisome position: 74.22

GC content: 71.12

Gene sequence:

>1077_bases
ATGGGCCTGACCACCATGACGGTCCGCGACGACGGCGCGCCGGTCGGTGCGCCGGCCGAGGCGGTCCGGTCCGATTACGG
TCCGGTCGATCCGGTGCTCGCGGTCAACGGCGAGCGCCGGGCCCGGCCGGTTGCGGTGGAATACAAGCAGTTTCACGGCG
CCGACGCGCAGTCGGCGCGCCGGTTCTTCGCCACGGCCTATGACCCGGGCTGGCGGATCGCCGGGGTGACCAACCACTGC
GTCGTGTCGCATCGGCGCAGCGACACCGGATCGATGACGGTCGACGAGGTGGCCATCCAGGGCAGGATGACCCTCGAGAT
CCCGGCGGGCGACACCGTCGTCGTGATCCAGCCGCGGGCCGGTGCGCTCAACGTGGCCGGCGGCCCGCTGGCCACCCCCG
ACTTCCCGCTCCTCGTCGCCCACGGCATGGCCTGCGTATTGCATTGCCACGGAGCGCGTTTCGATGTGGTGACCATCGCG
GCGGAGGTGCTGCAGAAAGTCGCCGCGGAATGGCACACCGCGTTGTCGCAACAGACCCAGTTCCTGAACTGGCGGCCGCG
CTCGCGGGCCGCGGTGCGGGCCTGGCATCGCGCGCTGGACTACGCGATGGCGACGCTCGCCTCGCCCGACACCGCCCGGC
AACCGCTGATCGCCGCCGGGATGGCCGGCCTGCTGGCCGGCGCGCTGCTCGAGTGCTATCCGTCCAACCTGACCGAGCAG
GATCCGGTCAGCGATCTCGCCCTGCCCGAAACCCTCAAGGAGGCGGTGTCTTTCATCCACCGCCACGCCACCGAGGACAT
CGGCATCAACGATGTCGCGGCCGCGGTGCACCTGACGCCCCGCGCGGTGCAGTACCTGTTCCGCCGCCAGCTCGACACCA
CCCCGACCGAGTACATGCGCCGGGTCCGGCTCAGCCGCGCGCACCAGGAGCTGGTGGCCGCGACGACCGCCTCCTCGACG
GTCACCGAAATCGCCCAGCGCTGGGGGTTCGCGCACACCGGACGGTTCGCGGTGCTCTACCGGCAGACCTACGGACAGAG
CCCGCACACCACGCTGCGGCAACAGACGGCGGTGTGA

Upstream 100 bases:

>100_bases
ATCTACCAAAGCCTCGGGGTGCACGAGCCGGCCGCGCCCCTCGACGGCGACGCGGTGCTGCGATGACGCGCCCGCCCACG
GTCTTCCCCCCGGGCCGGTC

Downstream 100 bases:

>100_bases
CGGAAGCGCGAGAGATAAGAATCGTTTGCCCGATTTACCAAAAGCGAACCGAACTTGGCGATAAGATCGTCTGATCCTTT
AGCTGCGGCGACGGGGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MGLTTMTVRDDGAPVGAPAEAVRSDYGPVDPVLAVNGERRARPVAVEYKQFHGADAQSARRFFATAYDPGWRIAGVTNHC
VVSHRRSDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRAGALNVAGGPLATPDFPLLVAHGMACVLHCHGARFDVVTIA
AEVLQKVAAEWHTALSQQTQFLNWRPRSRAAVRAWHRALDYAMATLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQ
DPVSDLALPETLKEAVSFIHRHATEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAATTASST
VTEIAQRWGFAHTGRFAVLYRQTYGQSPHTTLRQQTAV

Sequences:

>Translated_358_residues
MGLTTMTVRDDGAPVGAPAEAVRSDYGPVDPVLAVNGERRARPVAVEYKQFHGADAQSARRFFATAYDPGWRIAGVTNHC
VVSHRRSDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRAGALNVAGGPLATPDFPLLVAHGMACVLHCHGARFDVVTIA
AEVLQKVAAEWHTALSQQTQFLNWRPRSRAAVRAWHRALDYAMATLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQ
DPVSDLALPETLKEAVSFIHRHATEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAATTASST
VTEIAQRWGFAHTGRFAVLYRQTYGQSPHTTLRQQTAV
>Mature_357_residues
GLTTMTVRDDGAPVGAPAEAVRSDYGPVDPVLAVNGERRARPVAVEYKQFHGADAQSARRFFATAYDPGWRIAGVTNHCV
VSHRRSDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRAGALNVAGGPLATPDFPLLVAHGMACVLHCHGARFDVVTIAA
EVLQKVAAEWHTALSQQTQFLNWRPRSRAAVRAWHRALDYAMATLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQD
PVSDLALPETLKEAVSFIHRHATEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAATTASSTV
TEIAQRWGFAHTGRFAVLYRQTYGQSPHTTLRQQTAV

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=180, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38886; Mature: 38754

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTTMTVRDDGAPVGAPAEAVRSDYGPVDPVLAVNGERRARPVAVEYKQFHGADAQSAR
CCCEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEECCCCCCCCEEEEHHHHCCCCHHHHH
RFFATAYDPGWRIAGVTNHCVVSHRRSDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRA
HHHHEECCCCCEEECCCCHHEEECCCCCCCCEEHHHHHCCCEEEEEECCCCEEEEEECCC
GALNVAGGPLATPDFPLLVAHGMACVLHCHGARFDVVTIAAEVLQKVAAEWHTALSQQTQ
CEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNWRPRSRAAVRAWHRALDYAMATLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQ
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DPVSDLALPETLKEAVSFIHRHATEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMR
CCCHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
RVRLSRAHQELVAATTASSTVTEIAQRWGFAHTGRFAVLYRQTYGQSPHTTLRQQTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCHHHHHHCCC
>Mature Secondary Structure 
GLTTMTVRDDGAPVGAPAEAVRSDYGPVDPVLAVNGERRARPVAVEYKQFHGADAQSAR
CCEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEECCCCCCCCEEEEHHHHCCCCHHHHH
RFFATAYDPGWRIAGVTNHCVVSHRRSDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRA
HHHHEECCCCCEEECCCCHHEEECCCCCCCCEEHHHHHCCCEEEEEECCCCEEEEEECCC
GALNVAGGPLATPDFPLLVAHGMACVLHCHGARFDVVTIAAEVLQKVAAEWHTALSQQTQ
CEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNWRPRSRAAVRAWHRALDYAMATLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQ
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DPVSDLALPETLKEAVSFIHRHATEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMR
CCCHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
RVRLSRAHQELVAATTASSTVTEIAQRWGFAHTGRFAVLYRQTYGQSPHTTLRQQTAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]