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The map label for this gene is fadE24

Identifier: 41409286

GI number: 41409286

Start: 3538133

End: 3539524

Strand: Direct

Name: fadE24

Synonym: MAP3188

Alternate gene names: 41409286

Gene position: 3538133-3539524 (Clockwise)

Preceding gene: 41409285

Following gene: 41409287

Centisome position: 73.26

GC content: 70.62

Gene sequence:

>1392_bases
ATGACCGATTCCGGTTCCACCAAGACCCCCGCCCGCGTCAAACGGCGTGACCGCCAGTCCGGCGTCGGGCTGCAACCGCA
CAAACGCACGGGCATCGACATCGCCATCGCGCTGCTCACCCCGTTGGTCGGGCAGGAGTTCCTGGACAAATACCATCTGC
GCGACCCGCTCAACCGGGGCCTGCGGTACGGCACCAAGACCATCTTCTCCACCGGCGCCGCCACGTCCCGGCAGTTCAAG
CGGGTACAGAACCTGCGCGGCGGGCCGACCCGGCTCAAGTCCAGCGGCAAGGACTACTTCGACCTGACCCCCGACGACGA
GCAGAAGATGATCGTCGAGACGCTCGACGAATTCGCCGCCGAGGTGCTGCGGCCCGCCGCCCACGACGCCGACGAGGCGG
CGACCTACCCGCGCGACCTGATCGCCAAGGCCGCCGAGCTGGGCATCACCGCGATCAACATCCCCGAGGACTTCGACGGC
ATCGCCGCGCACCGCTCCAGCGTGACCAACGTGCTGGTCGCCGAGGCGCTGGCGTACGGCGACATGGGCCTGGCGCTGCC
GCTGCTGGCCCCGGGCGGCGTGGCCTCCGCGCTGACCCATTGGGGCAGCGCCGAGCAGCAGGCCACCTATCTGCCGGAGT
TCGCCGGCGAGAACGTGCCACAGGCCTGCGTGGCCATCGCCGAACCGCAACCGCTGTTCGACCCCACCCGGCTGAAGACC
ACCGCGGTGCGCACCCCGAGCGGATACCGCCTCGACGGGGTGAAGTCCCTGGTGCCCGCCGCCGCCGACGCCGAGCTGTT
CATCGTCGGCGCGCAGCTGGACGGCAAGCCGGCCCTGTTCATCGTCGAATCCTCGACGAAAGGCCTTACCGTGAAAGCGG
ATCCGAGCATGGGAATCCGGGCGGCGGAGCTGGGCCACGTCGAACTGTCCGGGGTGACGGTGCCGCTGGGTGCCCGGCTC
GGCGAGGACGAGGCCACCGACGACGACTACTCCGAGGCGATCGCCCTGTCCCGGCTGGGCTGGGCGGCGCTGACCGTCGG
GACGTCGCACGCGGTGCTCGACTATGTGGTGCCCTACGTGAAGGAACGCGAGGCCTTCGGCGAGCCGATCGCGCGCCGGC
AGGCGGTCGCCTTCATGTGCGCCAACATCGCCATCGAGTTGGACGGGCTGCGGCTGATCACCTGGCGCGGCGCGGCGCGC
GCCGAACAGGGCCTGCCGTTCGCCCGCGAGGCGGCGCTGGCCAAACGGCTCGGCGCCGACAAGGGCATGCAGATCGGCTC
CGACGGCGTCCAGCTGCTCGGCGGCCACGGCTACACCAAGGAGCACCCGGTCGAACGCTGGTACCGCGACCTGCGGGCCA
TCGGCGTCGCCGAGGGCGTCGTGGTCATCTGA

Upstream 100 bases:

>100_bases
CGCCTCGCACTGTGAATTAGTTAACAAGTGTTCTCCATGATCTTACTCCGGAGTAAGATCGGCTCTATCCGCACTGCCCA
TCAACCTGAGGCTGCTGAAA

Downstream 100 bases:

>100_bases
GTCGTTAATGCAAGAACCGAGCTGAAAGTTCAATCATGGCAATCAATCTGGAACTTCCCCGCAAGATGCAGGCGGTGACC
ACGAAGACGCATCAGGGCGC

Product: FadE24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTDSGSTKTPARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQEFLDKYHLRDPLNRGLRYGTKTIFSTGAATSRQFK
RVQNLRGGPTRLKSSGKDYFDLTPDDEQKMIVETLDEFAAEVLRPAAHDADEAATYPRDLIAKAAELGITAINIPEDFDG
IAAHRSSVTNVLVAEALAYGDMGLALPLLAPGGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKT
TAVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTVKADPSMGIRAAELGHVELSGVTVPLGARL
GEDEATDDDYSEAIALSRLGWAALTVGTSHAVLDYVVPYVKEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGAAR
AEQGLPFAREAALAKRLGADKGMQIGSDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI

Sequences:

>Translated_463_residues
MTDSGSTKTPARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQEFLDKYHLRDPLNRGLRYGTKTIFSTGAATSRQFK
RVQNLRGGPTRLKSSGKDYFDLTPDDEQKMIVETLDEFAAEVLRPAAHDADEAATYPRDLIAKAAELGITAINIPEDFDG
IAAHRSSVTNVLVAEALAYGDMGLALPLLAPGGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKT
TAVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTVKADPSMGIRAAELGHVELSGVTVPLGARL
GEDEATDDDYSEAIALSRLGWAALTVGTSHAVLDYVVPYVKEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGAAR
AEQGLPFAREAALAKRLGADKGMQIGSDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
>Mature_462_residues
TDSGSTKTPARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQEFLDKYHLRDPLNRGLRYGTKTIFSTGAATSRQFKR
VQNLRGGPTRLKSSGKDYFDLTPDDEQKMIVETLDEFAAEVLRPAAHDADEAATYPRDLIAKAAELGITAINIPEDFDGI
AAHRSSVTNVLVAEALAYGDMGLALPLLAPGGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKTT
AVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTVKADPSMGIRAAELGHVELSGVTVPLGARLG
EDEATDDDYSEAIALSRLGWAALTVGTSHAVLDYVVPYVKEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGAARA
EQGLPFAREAALAKRLGADKGMQIGSDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=31.7073170731707, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4557233, Length=367, Percent_Identity=28.8828337874659, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4557231, Length=400, Percent_Identity=28.5, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI187960098, Length=400, Percent_Identity=28.5, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=26.775956284153, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=26.1707988980716, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI76496475, Length=375, Percent_Identity=27.7333333333333, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4557235, Length=375, Percent_Identity=27.7333333333333, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI226958414, Length=332, Percent_Identity=26.5060240963855, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=26.3157894736842, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4503943, Length=398, Percent_Identity=27.8894472361809, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI7669494, Length=398, Percent_Identity=27.8894472361809, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=25.2873563218391, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=27.3224043715847, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786223, Length=368, Percent_Identity=26.6304347826087, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=31.9034852546917, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=32.4396782841823, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=30.1939058171745, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570075, Length=397, Percent_Identity=28.9672544080605, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17506239, Length=361, Percent_Identity=27.9778393351801, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17533517, Length=359, Percent_Identity=23.6768802228412, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=289, Percent_Identity=28.3737024221453, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=25.1322751322751, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=24.5231607629428, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=23.4666666666667, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=28.0172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=22.0108695652174, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=335, Percent_Identity=24.1791044776119, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=21.7391304347826, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=30.8743169398907, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=32.620320855615, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=29.1553133514986, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=28.4552845528455, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=26.0752688172043, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=26.0526315789474, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920834, Length=365, Percent_Identity=25.7534246575342, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 49540; Mature: 49409

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSGSTKTPARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQEFLDKYHLRDPLNRG
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LRYGTKTIFSTGAATSRQFKRVQNLRGGPTRLKSSGKDYFDLTPDDEQKMIVETLDEFAA
HHHCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
EVLRPAAHDADEAATYPRDLIAKAAELGITAINIPEDFDGIAAHRSSVTNVLVAEALAYG
HHHHHCCCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
DMGLALPLLAPGGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKT
CCCCCHHHCCCCHHHHHHHHCCCCCHHHHHCHHHCCCCCCHHHHEECCCCCCCCCCCCEE
TAVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTVKADPSMGIR
EEEECCCCCEECCHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCCE
AAELGHVELSGVTVPLGARLGEDEATDDDYSEAIALSRLGWAALTVGTSHAVLDYVVPYV
EECCCCEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
KEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGAARAEQGLPFAREAALAKRLGAD
HHHHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCC
KGMQIGSDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
CCCEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure 
TDSGSTKTPARVKRRDRQSGVGLQPHKRTGIDIAIALLTPLVGQEFLDKYHLRDPLNRG
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LRYGTKTIFSTGAATSRQFKRVQNLRGGPTRLKSSGKDYFDLTPDDEQKMIVETLDEFAA
HHHCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
EVLRPAAHDADEAATYPRDLIAKAAELGITAINIPEDFDGIAAHRSSVTNVLVAEALAYG
HHHHHCCCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
DMGLALPLLAPGGVASALTHWGSAEQQATYLPEFAGENVPQACVAIAEPQPLFDPTRLKT
CCCCCHHHCCCCHHHHHHHHCCCCCHHHHHCHHHCCCCCCHHHHEECCCCCCCCCCCCEE
TAVRTPSGYRLDGVKSLVPAAADAELFIVGAQLDGKPALFIVESSTKGLTVKADPSMGIR
EEEECCCCCEECCHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCCE
AAELGHVELSGVTVPLGARLGEDEATDDDYSEAIALSRLGWAALTVGTSHAVLDYVVPYV
EECCCCEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
KEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGAARAEQGLPFAREAALAKRLGAD
HHHHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCC
KGMQIGSDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
CCCEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]