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The map label for this gene is serB2

Identifier: 41409188

GI number: 41409188

Start: 3437140

End: 3438375

Strand: Reverse

Name: serB2

Synonym: MAP3090c

Alternate gene names: 41409188

Gene position: 3438375-3437140 (Counterclockwise)

Preceding gene: 41409189

Following gene: 41409187

Centisome position: 71.19

GC content: 71.84

Gene sequence:

>1236_bases
GTGAACTCACCACCCAAGGTGTCGGTGCTGATCACCGTCACCGGCGTGGACCAGCCGGGCGTGACGGCGACCCTGTTCGA
GGTGCTGTCGCGGCACGGGGTCGAGCTGCTCAACGTCGAACAGGTGGTGATCCGGCACCGGCTGACGCTGGGGGTGCTGG
TGTGCTGCCCCGCCGACGTCGCCGACGGGCCCGCGCTGCGCCACGACGTGGAGGCGGCCATCCGCAAGGTCGGCCTGGAC
GTCAGCATCGAACGCAGCGACGACGTGCCGATCATCCGGGAGCCCTCGACGCACACCATCTTCGTGCTGGGCCGGCCCAT
CACCGCGGCCGCGTTCGGTGCGGTGGCCCGCGAGGTGGCCGCGCTGGGCGTCAACATCGACCTGATCCGTGGCGTGTCCG
ACTATCCGGTGATCGGGCTGGAGCTGCGGGTCTCGGTGCCGCCGGGGGCCGACGGGGCGCTGCGCACCGCGCTGAACCGG
GTGTCCAGCGAGGAGCACGTCGACGTCGCCGTCGAGGACTACACCCTGGAACGGCGGGCCAAGCGGCTCATCGTGTTCGA
CGTGGACTCGACGCTGGTGCAGGGCGAGGTCATCGAGATGCTGGCGGCCAAGGCGGGCGCCGAGGGCCAGGTCGCCGCGA
TCACCGACGCCGCGATGCGTGGCGAGCTGGACTTCGCGCAGTCGCTGCAGCAGCGGGTGGCCACGCTCGCCGGCCTGCCC
GCCACGGTGATCGACGAGGTGGCCGGCCAGCTGGAGCTGATGCCCGGCGCCCGGACCACGCTGCGCACGCTGCGCCGGCT
GGGGTATGCCTGCGGCGTGGTGTCCGGGGGCTTCCGCCGGATCATCGAGCCGCTGGCCGAGGAGCTGATGCTGGACTACG
TGGCGGCCAATGAGCTGGAGATCGTGGACGGCACACTCACCGGCCGGGTGGTCGGTCCCATCATCGATCGGGCCGGAAAG
GCCACGGCGCTAAGGGAATTCGCGCAGCGGGCCGGGGTGCCCATGGCGCAGACCGTCGCCGTGGGCGACGGCGCCAACGA
CATCGACATGCTGGCCGCGGCCGGGCTGGGCATCGCGTTCAACGCCAAGCCGGCGCTGCGCGAGGTCGCCGACGCGTCGC
TGAGCCACCCGTATCTGGACACGGTGCTGTTCCTGCTGGGGGTGACCCGCGGCGAGATCGAGGCCGCCGACGCGATCGAC
GGCGAGGTGCGCCGGGTGGAGATCCCGCCGGAGTAA

Upstream 100 bases:

>100_bases
GGCGCACGTGGGTCGCGCGCACGGCCCGGCGGACAAGGACGTCACCCGGCTGGACGACGTCCAGGTTCGCAGCTGATGGC
CTGACGGGCGGCTGCCGGGC

Downstream 100 bases:

>100_bases
GCGCGGCGAGTAATCGCGGCGACCCGGCAGGTGTGCGGGCGTCGCGGTACGGCACGATGGTCGGGTGCCCGAAAACGACA
GTGCGGCAGCCGACCCTGAT

Product: SerB2

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNSPPKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLD
VSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNR
VSSEEHVDVAVEDYTLERRAKRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLP
ATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRIIEPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGK
ATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAID
GEVRRVEIPPE

Sequences:

>Translated_411_residues
MNSPPKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLD
VSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNR
VSSEEHVDVAVEDYTLERRAKRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLP
ATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRIIEPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGK
ATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAID
GEVRRVEIPPE
>Mature_411_residues
MNSPPKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLD
VSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNR
VSSEEHVDVAVEDYTLERRAKRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLP
ATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRIIEPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGK
ATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAID
GEVRRVEIPPE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=212, Percent_Identity=28.7735849056604, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790849, Length=255, Percent_Identity=43.921568627451, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321647, Length=237, Percent_Identity=41.7721518987342, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43439; Mature: 43439

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPPKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADV
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHHHEEEEECCCCC
ADGPALRHDVEAAIRKVGLDVSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVA
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHH
ALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNRVSSEEHVDVAVEDYTLERRA
HHCCCCEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHC
KRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLP
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCC
ATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRIIEPLAEELMLDYVAANELE
HHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IVDGTLTGRVVGPIIDRAGKATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAF
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCEEE
NAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAIDGEVRRVEIPPE
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MNSPPKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADV
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECHHHHHHHHHHHHEEEEECCCCC
ADGPALRHDVEAAIRKVGLDVSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVA
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHH
ALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNRVSSEEHVDVAVEDYTLERRA
HHCCCCEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHC
KRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLP
CEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHCCC
ATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVSGGFRRIIEPLAEELMLDYVAANELE
HHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IVDGTLTGRVVGPIIDRAGKATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAF
EEECCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCEEE
NAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAIDGEVRRVEIPPE
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA