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The map label for this gene is fixB

Identifier: 41409158

GI number: 41409158

Start: 3404899

End: 3405855

Strand: Reverse

Name: fixB

Synonym: MAP3060c

Alternate gene names: 41409158

Gene position: 3405855-3404899 (Counterclockwise)

Preceding gene: 41409159

Following gene: 41409157

Centisome position: 70.52

GC content: 71.68

Gene sequence:

>957_bases
ATGGCTGAAGTATTGGTGCTCGTGGAGCACGCCGAGGGTGCACTGAAGAAGGTCACCTCCGAACTGATCACCGCCGCCCG
GGCGCTGGGCGAGCCGTCGGCCGTCGTGGTCGGCACGCCGGGAACGGCCGCGCCGCTGGTCGACGGGCTGAAGGAGGCCG
GCGCCGCCAAGATCTACGTCGCCGAGTCCGACGACGTCGACAAGTACCTGATCACCCCGGTGGTCGACGTGCTGGCGTCG
CTGGCCGAGTCGAACGCCCCGGCCGCCGTGCTGCTGGCCGCCAACGCCGACGGCAAGGAGATCGCCGGCCGGCTCGCCGC
CTGGATCGGCTCCGGGCTGCTGGTCGACGTGGTCGAGGTCAAGGAGGGCGCCAAGGCCGTGCACTCCATCTTCGGTGGCG
CGTTCACCGTCGAGGCGCAGGCCAACGGCGACACCCCGGTGATCACGCTGCGCGCCGGTGCCGTCGACGCCGAGCCGGCC
GCCGGCGCGGGCGAGCAGGTCACCGTCGAGGTCCCGGCCGCCGCCGAGAACGCCACCAAGATCACCGCCCGCGAGCCCGC
GGTCGCCGGTGACCGCCCCGAGTTGACCGAGGCCAGCATCGTGGTCTCCGGTGGCCGCGGCGTGGGCAGCGCGGAGAACT
TCAAGGTGGTCGAGGAGCTGGCCGACGCGCTCGGCGCGGCCGTCGGCGCCTCGCGTGCCGCCGTCGACTCCGGCTACTAC
CCGGGCCAGTTCCAGGTGGGCCAGACCGGTAAGACGGTGTCGCCGCAGCTCTACATCGCGCTGGGCATCTCCGGCGCGAT
CCAGCACCGCGCGGGCATGCAGACGTCCAAGACCATCGTCGCGGTCAACAAGGACGAAGAGGCGCCGATCTTCGAGATCG
CCGACTACGGCGTGGTGGGCGACCTGTTCAAGGTCGCCCCGCAGCTGACCGAGGCGATCAAGGCCCGCAAGGGCTGA

Upstream 100 bases:

>100_bases
CGACGAGGGCGAGGGCGGCAACCAGATCGCCCAGTACCTGGTCGGCCAGAAGATCATCTAAGACGAGCCCACATCCCACA
GACGAGAAGAGCGATAAACC

Downstream 100 bases:

>100_bases
TAGCCGCGCGAGCAGACGCAAAAGCCCCCGACTCCCCGGCGTGTCGGGGGCTTTTGCGTCTGCTGGGCCCGAGGTAACGG
CGGTCACGCTTTTCGCCACA

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAEVLVLVEHAEGALKKVTSELITAARALGEPSAVVVGTPGTAAPLVDGLKEAGAAKIYVAESDDVDKYLITPVVDVLAS
LAESNAPAAVLLAANADGKEIAGRLAAWIGSGLLVDVVEVKEGAKAVHSIFGGAFTVEAQANGDTPVITLRAGAVDAEPA
AGAGEQVTVEVPAAAENATKITAREPAVAGDRPELTEASIVVSGGRGVGSAENFKVVEELADALGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG

Sequences:

>Translated_318_residues
MAEVLVLVEHAEGALKKVTSELITAARALGEPSAVVVGTPGTAAPLVDGLKEAGAAKIYVAESDDVDKYLITPVVDVLAS
LAESNAPAAVLLAANADGKEIAGRLAAWIGSGLLVDVVEVKEGAKAVHSIFGGAFTVEAQANGDTPVITLRAGAVDAEPA
AGAGEQVTVEVPAAAENATKITAREPAVAGDRPELTEASIVVSGGRGVGSAENFKVVEELADALGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG
>Mature_317_residues
AEVLVLVEHAEGALKKVTSELITAARALGEPSAVVVGTPGTAAPLVDGLKEAGAAKIYVAESDDVDKYLITPVVDVLASL
AESNAPAAVLLAANADGKEIAGRLAAWIGSGLLVDVVEVKEGAKAVHSIFGGAFTVEAQANGDTPVITLRAGAVDAEPAA
GAGEQVTVEVPAAAENATKITAREPAVAGDRPELTEASIVVSGGRGVGSAENFKVVEELADALGAAVGASRAAVDSGYYP
GQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=323, Percent_Identity=43.9628482972136, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI189181759, Length=274, Percent_Identity=45.6204379562044, Blast_Score=211, Evalue=8e-55,
Organism=Escherichia coli, GI1786226, Length=256, Percent_Identity=37.5, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787990, Length=240, Percent_Identity=35.4166666666667, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082157, Length=245, Percent_Identity=31.0204081632653, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=319, Percent_Identity=40.1253918495298, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6325261, Length=323, Percent_Identity=35.6037151702786, Blast_Score=177, Evalue=2e-45,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=42.1725239616613, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=42.1725239616613, Blast_Score=212, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32086; Mature: 31954

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVLVEHAEGALKKVTSELITAARALGEPSAVVVGTPGTAAPLVDGLKEAGAAKIYV
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
AESDDVDKYLITPVVDVLASLAESNAPAAVLLAANADGKEIAGRLAAWIGSGLLVDVVEV
ECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHH
KEGAKAVHSIFGGAFTVEAQANGDTPVITLRAGAVDAEPAAGAGEQVTVEVPAAAENATK
HHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEE
ITAREPAVAGDRPELTEASIVVSGGRGVGSAENFKVVEELADALGAAVGASRAAVDSGYY
EEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCCCHHH
DLFKVAPQLTEAIKARKG
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLVLVEHAEGALKKVTSELITAARALGEPSAVVVGTPGTAAPLVDGLKEAGAAKIYV
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
AESDDVDKYLITPVVDVLASLAESNAPAAVLLAANADGKEIAGRLAAWIGSGLLVDVVEV
ECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHH
KEGAKAVHSIFGGAFTVEAQANGDTPVITLRAGAVDAEPAAGAGEQVTVEVPAAAENATK
HHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEE
ITAREPAVAGDRPELTEASIVVSGGRGVGSAENFKVVEELADALGAAVGASRAAVDSGYY
EEECCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCCCHHH
DLFKVAPQLTEAIKARKG
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]