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The map label for this gene is ltp1

Identifier: 41408995

GI number: 41408995

Start: 3227077

End: 3228267

Strand: Reverse

Name: ltp1

Synonym: MAP2897c

Alternate gene names: 41408995

Gene position: 3228267-3227077 (Counterclockwise)

Preceding gene: 41408996

Following gene: 41408994

Centisome position: 66.84

GC content: 67.0

Gene sequence:

>1191_bases
ATGTCCAACAAGGTTTACGTCGTCGGCGTCGGCATGACGAAATTCGAGAAGCCCGGTCGCCGCGAGGGCTGGGACTATCC
GGACATGGCGCGCGAGTCGGGGACCAACGCGCTGGCCGACGCCGGCATCGACTACCGCGAGGTGCAGCAAGGCTACGTCG
GCTACGTCGCCGGCGACTCGACGTCCGGCCAGCGCGCACTCTACGAGCTGGGCATGACCGGCATCCCGATCGTCAACGTC
AACAACAACTGCTCCACCGGTTCGACCGCGCTCTTCCTGGCCGCCCAGGCCATCCGCGGCGGGCTCGTCGACTGCGCGAT
CGCGCTGGGTTTCGAGAAGATGCAACCGGGCTCGCTGGGCGGCGGCGCCCAGGACCGCGAATCGCCGATGGGCAGGCACG
TCAAGGCGATGGCCGAGATCGACGAGTTCGCCATGCCCGTCGCGCCCTGGATGTTCGGCGCCGCCGGCCGCGAGCACATG
CGCCAATACGGCAGCACCGCAGAGCATTTCGCCAAGATCGGCTATAAGAACCACAAGCATTCGGTGAACAACCCGTTCGC
CCAGTTCCAGGAGTCCTACACGCTCGAGGACATCCTGGCCGCGCGGATGATCTCCGACCCGCTGACCAAGCTGCAGTGCT
CGCCCACCTCGGACGGCTCGGGCGCGGCGATCCTGGCCAGCGAGGCGTTCGTCGACAAGCACGGGCTGGCCGGCCAGGCG
GTGGAGATCGTCGGCCAGGCCATGACGACGGACTTCGCCTCGACGTTCGACGGCAGCGCGAAGAACCTCATCGGCTACGA
CATGAATGTGCAAGCGGCGCAACAGGTTTACAACCAATGCGGGTTGGGGCCGCAGGATTTCCAGGTGATCGAGCTGCACG
ACTGCTTCTCGGCCAACGAACTTCTGCTCTATGAAGCCCTCGGCTTGTGCGGCCCGGGCGAGGCGCCCAAGCTGATCGAC
AACGGCGACACCACCTACGGCGGGCGCTGGGTGGTCAACCCGTCCGGCGGCCTGATCTCCAAGGGGCACCCGCTGGGCGC
CACCGGGCTGGCGCAATGCGCCGAGCTGACCTGGCAGCTGCGCGGCACCGCGGACAAACGTCAGGTCGAAAACGTCAGCG
CCGCACTGCAACACAACATCGGGCTGGGCGGCGCGGCCGTCGTCACCGCCTACCAGCGCGCCGAACGCTAA

Upstream 100 bases:

>100_bases
ACGCTTTAGCCGCCGGGCCCACGCTTTAGCTGCCCCGGCCCAACGGTTGGTCGGGCCACGTTGCACACTGAGAGCCTGAG
CCGTTGGGAAGGGGACAAAG

Downstream 100 bases:

>100_bases
GCGCGCCATGATCGAATGGTCCGACACCGACCTGATGGTCCGCGACGCCGTCCGGCAATTCGTGGACAAGGAGATCCGGC
CGCACCTGGACGAATTGGAA

Product: lipid-transfer protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSNKVYVVGVGMTKFEKPGRREGWDYPDMARESGTNALADAGIDYREVQQGYVGYVAGDSTSGQRALYELGMTGIPIVNV
NNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGGAQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHM
RQYGSTAEHFAKIGYKNHKHSVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTSDGSGAAILASEAFVDKHGLAGQA
VEIVGQAMTTDFASTFDGSAKNLIGYDMNVQAAQQVYNQCGLGPQDFQVIELHDCFSANELLLYEALGLCGPGEAPKLID
NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTADKRQVENVSAALQHNIGLGGAAVVTAYQRAER

Sequences:

>Translated_396_residues
MSNKVYVVGVGMTKFEKPGRREGWDYPDMARESGTNALADAGIDYREVQQGYVGYVAGDSTSGQRALYELGMTGIPIVNV
NNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGGAQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHM
RQYGSTAEHFAKIGYKNHKHSVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTSDGSGAAILASEAFVDKHGLAGQA
VEIVGQAMTTDFASTFDGSAKNLIGYDMNVQAAQQVYNQCGLGPQDFQVIELHDCFSANELLLYEALGLCGPGEAPKLID
NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTADKRQVENVSAALQHNIGLGGAAVVTAYQRAER
>Mature_395_residues
SNKVYVVGVGMTKFEKPGRREGWDYPDMARESGTNALADAGIDYREVQQGYVGYVAGDSTSGQRALYELGMTGIPIVNVN
NNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGGAQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHMR
QYGSTAEHFAKIGYKNHKHSVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTSDGSGAAILASEAFVDKHGLAGQAV
EIVGQAMTTDFASTFDGSAKNLIGYDMNVQAAQQVYNQCGLGPQDFQVIELHDCFSANELLLYEALGLCGPGEAPKLIDN
GDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTADKRQVENVSAALQHNIGLGGAAVVTAYQRAER

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=394, Percent_Identity=62.6903553299492, Blast_Score=494, Evalue=1e-140,
Organism=Homo sapiens, GI302344760, Length=394, Percent_Identity=59.3908629441624, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI302344767, Length=325, Percent_Identity=62.4615384615385, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI302344762, Length=393, Percent_Identity=54.1984732824427, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI55956775, Length=355, Percent_Identity=51.830985915493, Blast_Score=344, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI17537653, Length=382, Percent_Identity=53.1413612565445, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24585051, Length=394, Percent_Identity=64.7208121827411, Blast_Score=519, Evalue=1e-147,
Organism=Drosophila melanogaster, GI19921506, Length=394, Percent_Identity=63.7055837563452, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 42130; Mature: 41999

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKVYVVGVGMTKFEKPGRREGWDYPDMARESGTNALADAGIDYREVQQGYVGYVAGDS
CCCCEEEEEECHHHCCCCCCCCCCCCCHHHHHCCCCHHHHCCCCHHHHHCCCEEEEECCC
TSGQRALYELGMTGIPIVNVNNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLG
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHCCCCCCC
GGAQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHMRQYGSTAEHFAKIGYKNHKH
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCC
SVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTSDGSGAAILASEAFVDKHGLAGQA
CCCCHHHHHHHCCCHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEHHHHHHHCCCCHHH
VEIVGQAMTTDFASTFDGSAKNLIGYDMNVQAAQQVYNQCGLGPQDFQVIELHDCFSANE
HHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
LLLYEALGLCGPGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
HHHHHHHCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGTADKRQVENVSAALQHNIGLGGAAVVTAYQRAER
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNKVYVVGVGMTKFEKPGRREGWDYPDMARESGTNALADAGIDYREVQQGYVGYVAGDS
CCCEEEEEECHHHCCCCCCCCCCCCCHHHHHCCCCHHHHCCCCHHHHHCCCEEEEECCC
TSGQRALYELGMTGIPIVNVNNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLG
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHCCCCCCC
GGAQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHMRQYGSTAEHFAKIGYKNHKH
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCC
SVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTSDGSGAAILASEAFVDKHGLAGQA
CCCCHHHHHHHCCCHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEHHHHHHHCCCCHHH
VEIVGQAMTTDFASTFDGSAKNLIGYDMNVQAAQQVYNQCGLGPQDFQVIELHDCFSANE
HHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
LLLYEALGLCGPGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQL
HHHHHHHCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGTADKRQVENVSAALQHNIGLGGAAVVTAYQRAER
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]