| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is pks2 [H]
Identifier: 41408701
GI number: 41408701
Start: 2929382
End: 2933392
Strand: Reverse
Name: pks2 [H]
Synonym: MAP2603c
Alternate gene names: 41408701
Gene position: 2933392-2929382 (Counterclockwise)
Preceding gene: 41408702
Following gene: 41408697
Centisome position: 60.74
GC content: 73.2
Gene sequence:
>4011_bases GTGCGATTCGCGGCGGCCGTGCAGGCCGCGCTCAAGGACGGATTCCGTGTGTTCGGTGAGCTGGCGCCGCATCCGTTGCT CACCCATGCCGTCGAGCAGAACGCCGCCAGCCTGGACGTGCCGATCGCCGCGCTGGCCGCGATGCGCCGCGAGCAGGAGC TGCCACTGGGGTTGCGCGGCTTCGTCGGTGACCTGCACAGTGCCGGCGCCCTGGTCGACTTCTCGGTGCAGTACCCCGCC GGGCGATTGGTGGATGCGCCGCTGCCCACCTGGTCGCACCGGCGGCTGATGCTTCGCCGCGAGTCGGTGCAGCGGGCGCA CGGCTCGTCGGTCCAGGCGGTGCACCCGCTGCTCGGGGCGCACGTGCACCTGCGGGAGGAACCGGAACGGCACGTGTGGC AGGGCGAGGTCGGCACCGACGCCCACCCCTGGCTCGCCGATCACCAAATCCACGGTGTCGCAGCGTTTCCCGGCGCCGGC TACTGCGAGATGGCGCTGGCGGCCGCCGCCGCGACGCTCGGTGAGCGCGCCGAGGTGCGCGACGTCACGTTCGAGCAGAC CCTGCTGCTGGCCGGCCGGACGGAGGTCTCCTCGACGGCGACGGTGACCGGGCCCGGGCGGCTCGAGTTCACCGTGGACA CCCACGAAGACGGCGAGCGCATCCGGCGGGCCGGCGCGGTCCTGCACGCCTTGCCGCCAGAGCACGGCGGCGAGACCGGG CCGCCCGCGCACGACGTGGCAACGCTGATCGCCGACCACCCGTCCCGCATTGAGGGCGCCGAGTTGCGAAAGGCGTTCGG CGCCATAGGTATTCAGTACGGCCCGGCCTTTTCGGGTCTGGCCGCGGTGCTGGTCGGCGACCGGGACGTCGGCACCGTGC TCGCCGAGGTGGCGCTGCCGGGCGCGATCCGCTCACAGCAGTCGGGTTATGGCGCGCACCCGGCCCTGCTGGACGCGTGC TTGCAGTCCGTCATCGCCGCGCCCGAGCTGCAGCGGGCGGCAGCCGGCGGTCTGCTGCTGCCGGTGGGGGTGCGCCGGCT GCGCAACTATCACTCGACGCGCAACGCGCACTACTGCCTCACCCGGATCACGTCCTCGCGTCCCGGTGAGTGCGAGGCCG ACGTCGACGTGCTGGACCAATCCGGGACGGTGCTGCTGACGGTCGAGGGGCTGCGGCTGGCCGGCGCGGCCTCCGAACAC GAACACGCCCAACGGCTGCTCGACGAGCGGCTGTTGACCATCGAGTGGGAAGCCCGGGAATTGCCCGAGGCGCCGCAGGG CGAGCCGGGCTCCTGGTTGCTGCTCAGCGCGTGCGACGCGGCGTCCAACGGCGATGACGCGTTGACGACGCAACTCGCCG ACGTCCTGAAAACCGATGGCGCGCAATGCCGTACCGTGTCCCTGCCGCCGGGGGCGGTGGGTACCGAAGAGCTGCGTTCG CTGCTGTCCGGCGGCGAGCCGGGCGGCAACGGTCACCGGCCGCTGCAGCGGCTCACCGGTGTCGTGGTGGTGGCCGCCGC CTCCGAGGCCGGCCACCCGGCCGCGCCGCGGCGCGGCCGGGACTACGTGTCGCACCTCGCGACCGTCGCCCGCGAGCTCT CGGAGCTACCCGGCGAATCGCCCCGGTTGTTCGTGCTGACCCGCAATGCCGCGGTAGTCGTCGCCGGCGATGCGCCCAAC CTGACCCAGGCCGGGCTGCGGGGGCTGATGCGGGTGATCGACGCCGAGCATCCGCACCTGAGCGCCACCCAGATCGACGT CGACGACGCCACCGACCCCGGACACGTTGCGCGGCAACTACAAAGCCGCTCCGGAGAAGACGAGACCGCCTGGCGCGACG GGCAGTGGTACACCGCGCGGCTGCGCCCCGGCCCGCTGCGGCCGGCCGACCGGCGAACCACCGTCGTCGATCACGGGCGC GACGGCATGCGGTTGCACATCCGCACGCCCGGCGACCTGGAATCGCTGGAACTCACCGCGTTCGACCGGGTGCCGCCCGG GCCGGGGGAGATCGAGGTGGCGGTCGCCTCGTCGACCATCAACTTCGCCGACGTCCTGGTGGCCTTCGGGCGCTACCCGA TGTTCGAGGGCTACCAGCAGCAATTGGGCGGCGACTTCGCCGGGGTGGTGACCGCCGTCGGACCGGGCGTCACCGAGCAC CGGGTCGGCGACCGCGTCGGCGGCCTGTCCGGGAACGGATGCTGGGGCACCTTCGTGCTCGCCGATGCCCGGCACGCGGT CACCCTGCCGCCGGAGATTCCGCTTCGGGACGCCGCCGCGGTGCCGACCGCATCGGCCACCGCCTGGTACGGCCTGCACG ACCTGGCCCGCATCGCGCCGACCGACAAGGTGCTGATCCACTCCGGGACCGGCGGCGTCGGGCAGGCGGCCATCGCCATC GCCCGGGCGGCAGGTTGCGAGATCTTCGCCACCGCGGGCAGCCCGCAACGCCGGCAACTGTTGCGCGACATGGGAATTGA GCACGTGTACGACTCGCGCAGCCTCGAGTTCGCCGAGCAGATTCGCCGTGACACCGACGGGTACGGCGTCGACGTGGTGC TCAACTCGCTGCCCGGCGCCGCGCAGCGCGCCGGGATCGAACTGCTGGCCCTGGGCGGGCGCTTCATCGAGCTGGGCAAG CGCGACATCTACCGCGACAGCCAGCTGGGGCTGTTCCCGTTCCGCCGCAACCTCTCGCTGTTCGCCGTCGACCTGGCGCT GCTGACCCACAGCCACCCGCACACCGTCCGGCGGCTGCTGACCACCGTGTACCAGCGCACCGCGGCCGGCGAGCTGCCGA TGCCGCGCACCACGCACTATCCGCTGCAGGACGCCGCCGCCGCGGTGCGCCTGGTCGCCGCGGCCGGGCACACCGGCAAG GTGGTGCTGCAGGTGCCGCGGACCGCCAGCAGCGTGGCCGCCCTGCCGCCGGAGAAGGTGCGGCCGTTCCGCGCGGACGG CGCCTACATCATCACCGGCGGCCTCGGCGGCCTGGGCCTGTTCCTGGCCGGCGAAATGGCTTGCCGCGACGGCGATGTGG GCGCCGGGCGGATCGTGCTCAACTCCCGCTCGCAACCCGGCGAGCAGGCCCGCCGGGCCATCGAGCGGCTGCGCGCCGCC GGGGCCGACATCGCGGTCGAGTGCGGCGACATCGCCGAGCCGGACACGGCCGAACGTCTGGTGACATGCGCGACCGCCAC CGGGCTGCCGGTTCGCGGGGTGCTGCACGCCGCGGCCGTCGTCGAGGACGCCACCCTGACCAACGTCACCGATGACCTCA TCGACCGGTGCTGGGCGCCAAAGGTGTACGGCGCGTGGAACCTTCACCAGGCCACCGCGGGGCAGCCGCTGGAGTGGTTC TGCCTGTTCTCCTCGGCCGCCGCGCTGGTGGGGTCTCCCGGGCAGGGGGCCTACGCGGCGGCCAACAGCTGGCTGGACGC GTTCGCCCGCTGGCGGCACGCCCGCGGCGCACCGGCCACCGCGATCGCGTGGGGGGCGTGGTCGCAGGTGGGCCGCGCCA CCGCCCTGGCCGAAGACGCCGGCGTCGCGATCACACCGGCCGAGGGGTTCCGCGCCTTCGAAACGCTGCTGCGCCACGAC CGCCCGTATGCGGGCTACGCGCCGATCATGGGCACGCCGTGGCTGACCTCCTTCGCGCAACGCAGCCCGTTCGCCGAGGC GTTCCGGTCGGCGGGGCAGGGCCGGCCGGACGCCGGCAAGTTCCTCGCCGAGCTGCGGGCGCTGCCGCGCGAAGAATGGC CGTCGGCCATCCGTCGGCTGGTGTCCGGGCAGCTCAGCCTCTTGCTGCGCCGCACAATCGATCCCGATCGGCCGCTGTCG GACTACGGCTTGGATTCGCTGGGCAACCTGGAGCTGCGCACCCGCATCGAAACCGAGACCGGGGTGCGCATCAGCCCCGC CACGATCACAACCGTGCGCGGTCTGGCGGAGCATTTGTGTGACGAGCTGGCCGATCTGCCAGCCGCGCCGCCGGCTGGTG CCCCGCGCTAG
Upstream 100 bases:
>100_bases GACGGCACCCGAGGTGCCGTACTACTCGGCGACCCTGTGAAATCCGCGCGAGCGACCGTCGTTCGGCGGCGACTACTGGG CCGAAAACCTGCGCCACACC
Downstream 100 bases:
>100_bases CCGGCCGCGCCGCGATCGCTGACGTCGTGATTGCCGGCCTGCCGGGCGCAGTGCGCGCCGCAGAACATCGCGCCGCCCGA TTCGACCCCGTGACCCAGGA
Product: hypothetical protein
Products: NADP(+); Semiquinone. [C]
Alternate protein names: Polyketide synthase pks2 [H]
Number of amino acids: Translated: 1336; Mature: 1336
Protein sequence:
>1336_residues MRFAAAVQAALKDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGFVGDLHSAGALVDFSVQYPA GRLVDAPLPTWSHRRLMLRRESVQRAHGSSVQAVHPLLGAHVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAG YCEMALAAAAATLGERAEVRDVTFEQTLLLAGRTEVSSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETG PPAHDVATLIADHPSRIEGAELRKAFGAIGIQYGPAFSGLAAVLVGDRDVGTVLAEVALPGAIRSQQSGYGAHPALLDAC LQSVIAAPELQRAAAGGLLLPVGVRRLRNYHSTRNAHYCLTRITSSRPGECEADVDVLDQSGTVLLTVEGLRLAGAASEH EHAQRLLDERLLTIEWEARELPEAPQGEPGSWLLLSACDAASNGDDALTTQLADVLKTDGAQCRTVSLPPGAVGTEELRS LLSGGEPGGNGHRPLQRLTGVVVVAAASEAGHPAAPRRGRDYVSHLATVARELSELPGESPRLFVLTRNAAVVVAGDAPN LTQAGLRGLMRVIDAEHPHLSATQIDVDDATDPGHVARQLQSRSGEDETAWRDGQWYTARLRPGPLRPADRRTTVVDHGR DGMRLHIRTPGDLESLELTAFDRVPPGPGEIEVAVASSTINFADVLVAFGRYPMFEGYQQQLGGDFAGVVTAVGPGVTEH RVGDRVGGLSGNGCWGTFVLADARHAVTLPPEIPLRDAAAVPTASATAWYGLHDLARIAPTDKVLIHSGTGGVGQAAIAI ARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQIRRDTDGYGVDVVLNSLPGAAQRAGIELLALGGRFIELGK RDIYRDSQLGLFPFRRNLSLFAVDLALLTHSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAAAAVRLVAAAGHTGK VVLQVPRTASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMACRDGDVGAGRIVLNSRSQPGEQARRAIERLRAA GADIAVECGDIAEPDTAERLVTCATATGLPVRGVLHAAAVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQATAGQPLEWF CLFSSAAALVGSPGQGAYAAANSWLDAFARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPAEGFRAFETLLRHD RPYAGYAPIMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLVSGQLSLLLRRTIDPDRPLS DYGLDSLGNLELRTRIETETGVRISPATITTVRGLAEHLCDELADLPAAPPAGAPR
Sequences:
>Translated_1336_residues MRFAAAVQAALKDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGFVGDLHSAGALVDFSVQYPA GRLVDAPLPTWSHRRLMLRRESVQRAHGSSVQAVHPLLGAHVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAG YCEMALAAAAATLGERAEVRDVTFEQTLLLAGRTEVSSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETG PPAHDVATLIADHPSRIEGAELRKAFGAIGIQYGPAFSGLAAVLVGDRDVGTVLAEVALPGAIRSQQSGYGAHPALLDAC LQSVIAAPELQRAAAGGLLLPVGVRRLRNYHSTRNAHYCLTRITSSRPGECEADVDVLDQSGTVLLTVEGLRLAGAASEH EHAQRLLDERLLTIEWEARELPEAPQGEPGSWLLLSACDAASNGDDALTTQLADVLKTDGAQCRTVSLPPGAVGTEELRS LLSGGEPGGNGHRPLQRLTGVVVVAAASEAGHPAAPRRGRDYVSHLATVARELSELPGESPRLFVLTRNAAVVVAGDAPN LTQAGLRGLMRVIDAEHPHLSATQIDVDDATDPGHVARQLQSRSGEDETAWRDGQWYTARLRPGPLRPADRRTTVVDHGR DGMRLHIRTPGDLESLELTAFDRVPPGPGEIEVAVASSTINFADVLVAFGRYPMFEGYQQQLGGDFAGVVTAVGPGVTEH RVGDRVGGLSGNGCWGTFVLADARHAVTLPPEIPLRDAAAVPTASATAWYGLHDLARIAPTDKVLIHSGTGGVGQAAIAI ARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQIRRDTDGYGVDVVLNSLPGAAQRAGIELLALGGRFIELGK RDIYRDSQLGLFPFRRNLSLFAVDLALLTHSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAAAAVRLVAAAGHTGK VVLQVPRTASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMACRDGDVGAGRIVLNSRSQPGEQARRAIERLRAA GADIAVECGDIAEPDTAERLVTCATATGLPVRGVLHAAAVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQATAGQPLEWF CLFSSAAALVGSPGQGAYAAANSWLDAFARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPAEGFRAFETLLRHD RPYAGYAPIMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLVSGQLSLLLRRTIDPDRPLS DYGLDSLGNLELRTRIETETGVRISPATITTVRGLAEHLCDELADLPAAPPAGAPR >Mature_1336_residues MRFAAAVQAALKDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGFVGDLHSAGALVDFSVQYPA GRLVDAPLPTWSHRRLMLRRESVQRAHGSSVQAVHPLLGAHVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAG YCEMALAAAAATLGERAEVRDVTFEQTLLLAGRTEVSSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETG PPAHDVATLIADHPSRIEGAELRKAFGAIGIQYGPAFSGLAAVLVGDRDVGTVLAEVALPGAIRSQQSGYGAHPALLDAC LQSVIAAPELQRAAAGGLLLPVGVRRLRNYHSTRNAHYCLTRITSSRPGECEADVDVLDQSGTVLLTVEGLRLAGAASEH EHAQRLLDERLLTIEWEARELPEAPQGEPGSWLLLSACDAASNGDDALTTQLADVLKTDGAQCRTVSLPPGAVGTEELRS LLSGGEPGGNGHRPLQRLTGVVVVAAASEAGHPAAPRRGRDYVSHLATVARELSELPGESPRLFVLTRNAAVVVAGDAPN LTQAGLRGLMRVIDAEHPHLSATQIDVDDATDPGHVARQLQSRSGEDETAWRDGQWYTARLRPGPLRPADRRTTVVDHGR DGMRLHIRTPGDLESLELTAFDRVPPGPGEIEVAVASSTINFADVLVAFGRYPMFEGYQQQLGGDFAGVVTAVGPGVTEH RVGDRVGGLSGNGCWGTFVLADARHAVTLPPEIPLRDAAAVPTASATAWYGLHDLARIAPTDKVLIHSGTGGVGQAAIAI ARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQIRRDTDGYGVDVVLNSLPGAAQRAGIELLALGGRFIELGK RDIYRDSQLGLFPFRRNLSLFAVDLALLTHSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAAAAVRLVAAAGHTGK VVLQVPRTASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMACRDGDVGAGRIVLNSRSQPGEQARRAIERLRAA GADIAVECGDIAEPDTAERLVTCATATGLPVRGVLHAAAVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQATAGQPLEWF CLFSSAAALVGSPGQGAYAAANSWLDAFARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPAEGFRAFETLLRHD RPYAGYAPIMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLVSGQLSLLLRRTIDPDRPLS DYGLDSLGNLELRTRIETETGVRISPATITTVRGLAEHLCDELADLPAAPPAGAPR
Specific function: Catalyzes the synthesis of methyl phthioceranic acids and/or hydroxyphthioceranic acids that are the major acyl constituents of cell wall lipids [H]
COG id: COG3321
COG function: function code Q; Polyketide synthase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 acyl carrier domain [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=779, Percent_Identity=29.6534017971759, Blast_Score=209, Evalue=2e-53, Organism=Homo sapiens, GI22538446, Length=337, Percent_Identity=28.7833827893175, Blast_Score=124, Evalue=9e-28, Organism=Homo sapiens, GI22538444, Length=337, Percent_Identity=28.7833827893175, Blast_Score=124, Evalue=9e-28, Organism=Homo sapiens, GI18379349, Length=218, Percent_Identity=29.8165137614679, Blast_Score=102, Evalue=2e-21, Organism=Homo sapiens, GI194239674, Length=320, Percent_Identity=26.875, Blast_Score=100, Evalue=1e-20, Organism=Homo sapiens, GI13236495, Length=320, Percent_Identity=26.875, Blast_Score=100, Evalue=1e-20, Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=23.6467236467236, Blast_Score=97, Evalue=9e-20, Organism=Homo sapiens, GI67078404, Length=331, Percent_Identity=27.4924471299094, Blast_Score=91, Evalue=6e-18, Organism=Homo sapiens, GI67078406, Length=279, Percent_Identity=28.3154121863799, Blast_Score=85, Evalue=4e-16, Organism=Homo sapiens, GI194239676, Length=194, Percent_Identity=29.3814432989691, Blast_Score=80, Evalue=1e-14, Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-11, Organism=Homo sapiens, GI28557745, Length=339, Percent_Identity=22.7138643067847, Blast_Score=69, Evalue=3e-11, Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=27.4390243902439, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI212642053, Length=753, Percent_Identity=30.2788844621514, Blast_Score=206, Evalue=9e-53, Organism=Caenorhabditis elegans, GI17507255, Length=205, Percent_Identity=26.3414634146341, Blast_Score=68, Evalue=3e-11, Organism=Drosophila melanogaster, GI24581345, Length=617, Percent_Identity=30.1458670988655, Blast_Score=207, Evalue=6e-53, Organism=Drosophila melanogaster, GI19920632, Length=634, Percent_Identity=30.1261829652997, Blast_Score=195, Evalue=2e-49, Organism=Drosophila melanogaster, GI221330659, Length=634, Percent_Identity=30.1261829652997, Blast_Score=194, Evalue=4e-49,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR013149 - InterPro: IPR013154 - InterPro: IPR000794 - InterPro: IPR002198 - InterPro: IPR011032 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020842 - InterPro: IPR020801 - InterPro: IPR020807 - InterPro: IPR020843 - InterPro: IPR006162 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]
EC number: 1.6.5.5 [C]
Molecular weight: Translated: 141951; Mature: 141951
Theoretical pI: Translated: 6.38; Mature: 6.38
Prosite motif: PS50075 ACP_DOMAIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRFAAAVQAALKDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRG CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHH FVGDLHSAGALVDFSVQYPAGRLVDAPLPTWSHRRLMLRRESVQRAHGSSVQAVHPLLGA HHHHHHCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC HVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAGYCEMALAAAAATLGERAEVR EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHH DVTFEQTLLLAGRTEVSSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETG HCHHHHHEEEECCCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCC PPAHDVATLIADHPSRIEGAELRKAFGAIGIQYGPAFSGLAAVLVGDRDVGTVLAEVALP CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHCCEEEEECCCHHHHHHHHHHCC GAIRSQQSGYGAHPALLDACLQSVIAAPELQRAAAGGLLLPVGVRRLRNYHSTRNAHYCL CHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCEEHHHHHHHHHHHHHCCCCEEEE TRITSSRPGECEADVDVLDQSGTVLLTVEGLRLAGAASEHEHAQRLLDERLLTIEWEARE EECCCCCCCCCCCCHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHCCEEEEEECHHH LPEAPQGEPGSWLLLSACDAASNGDDALTTQLADVLKTDGAQCRTVSLPPGAVGTEELRS CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH LLSGGEPGGNGHRPLQRLTGVVVVAAASEAGHPAAPRRGRDYVSHLATVARELSELPGES HHCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC PRLFVLTRNAAVVVAGDAPNLTQAGLRGLMRVIDAEHPHLSATQIDVDDATDPGHVARQL CEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHH QSRSGEDETAWRDGQWYTARLRPGPLRPADRRTTVVDHGRDGMRLHIRTPGDLESLELTA HHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCEEEEE FDRVPPGPGEIEVAVASSTINFADVLVAFGRYPMFEGYQQQLGGDFAGVVTAVGPGVTEH ECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCCHHH RVGDRVGGLSGNGCWGTFVLADARHAVTLPPEIPLRDAAAVPTASATAWYGLHDLARIAP HHCHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC TDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQ CCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCHHHHHCCCHHHHHHH IRRDTDGYGVDVVLNSLPGAAQRAGIELLALGGRFIELGKRDIYRDSQLGLFPFRRNLSL HHHCCCCCCEEEHEECCCCHHHHCCEEEEEECCHHHHHCCHHHCCCCCCCCCCHHCCCCH FAVDLALLTHSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAAAAVRLVAAAGHTGK HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE VVLQVPRTASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMACRDGDVGAGRIVL EEEEECCCCHHHCCCCHHHCCCEECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEE NSRSQPGEQARRAIERLRAAGADIAVECGDIAEPDTAERLVTCATATGLPVRGVLHAAAV CCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH VEDATLTNVTDDLIDRCWAPKVYGAWNLHQATAGQPLEWFCLFSSAAALVGSPGQGAYAA HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCHHH ANSWLDAFARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPAEGFRAFETLLRHD HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCC RPYAGYAPIMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRL CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH VSGQLSLLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGVRISPATITTVRGLAEHLC HHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHH DELADLPAAPPAGAPR HHHHHCCCCCCCCCCC >Mature Secondary Structure MRFAAAVQAALKDGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRG CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHH FVGDLHSAGALVDFSVQYPAGRLVDAPLPTWSHRRLMLRRESVQRAHGSSVQAVHPLLGA HHHHHHCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCC HVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAGYCEMALAAAAATLGERAEVR EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHH DVTFEQTLLLAGRTEVSSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETG HCHHHHHEEEECCCCCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCC PPAHDVATLIADHPSRIEGAELRKAFGAIGIQYGPAFSGLAAVLVGDRDVGTVLAEVALP CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHCCEEEEECCCHHHHHHHHHHCC GAIRSQQSGYGAHPALLDACLQSVIAAPELQRAAAGGLLLPVGVRRLRNYHSTRNAHYCL CHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCEEHHHHHHHHHHHHHCCCCEEEE TRITSSRPGECEADVDVLDQSGTVLLTVEGLRLAGAASEHEHAQRLLDERLLTIEWEARE EECCCCCCCCCCCCHHHCCCCCCEEEEECCEEEECCCCHHHHHHHHHHCCEEEEEECHHH LPEAPQGEPGSWLLLSACDAASNGDDALTTQLADVLKTDGAQCRTVSLPPGAVGTEELRS CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH LLSGGEPGGNGHRPLQRLTGVVVVAAASEAGHPAAPRRGRDYVSHLATVARELSELPGES HHCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC PRLFVLTRNAAVVVAGDAPNLTQAGLRGLMRVIDAEHPHLSATQIDVDDATDPGHVARQL CEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHH QSRSGEDETAWRDGQWYTARLRPGPLRPADRRTTVVDHGRDGMRLHIRTPGDLESLELTA HHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCEEEEE FDRVPPGPGEIEVAVASSTINFADVLVAFGRYPMFEGYQQQLGGDFAGVVTAVGPGVTEH ECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCCHHH RVGDRVGGLSGNGCWGTFVLADARHAVTLPPEIPLRDAAAVPTASATAWYGLHDLARIAP HHCHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC TDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQ CCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCHHHHHCCCHHHHHHH IRRDTDGYGVDVVLNSLPGAAQRAGIELLALGGRFIELGKRDIYRDSQLGLFPFRRNLSL HHHCCCCCCEEEHEECCCCHHHHCCEEEEEECCHHHHHCCHHHCCCCCCCCCCHHCCCCH FAVDLALLTHSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAAAAVRLVAAAGHTGK HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE VVLQVPRTASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMACRDGDVGAGRIVL EEEEECCCCHHHCCCCHHHCCCEECCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEE NSRSQPGEQARRAIERLRAAGADIAVECGDIAEPDTAERLVTCATATGLPVRGVLHAAAV CCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH VEDATLTNVTDDLIDRCWAPKVYGAWNLHQATAGQPLEWFCLFSSAAALVGSPGQGAYAA HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCHHH ANSWLDAFARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPAEGFRAFETLLRHD HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCC RPYAGYAPIMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRL CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH VSGQLSLLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGVRISPATITTVRGLAEHLC HHHHHHHHHHHHCCCCCCCHHCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHH DELADLPAAPPAGAPR HHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.0024 {1,2-naphthoquinone}} 0.26 {1,4-naphthoquinone}} 0.065 {1,4-benzoquinone}} [C]
Substrates: NADPH; Quinone [C]
Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]
General reaction: Oxidation; Reduction [C]
Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]