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The map label for this gene is cysC [H]

Identifier: 41408697

GI number: 41408697

Start: 2924956

End: 2925648

Strand: Reverse

Name: cysC [H]

Synonym: MAP2599c

Alternate gene names: 41408697

Gene position: 2925648-2924956 (Counterclockwise)

Preceding gene: 41408701

Following gene: 41408696

Centisome position: 60.58

GC content: 66.67

Gene sequence:

>693_bases
ATGTCGAACAACATCACCTGGCACGAACACAAGATCAGCCGCGGCGAACGCGAGCAACTCAACGGCCACAAGGGCTGCGT
CATCTGGTTCACCGGGCTCAGCGGCAGCGGCAAGAGCACGGTCGCCAACGTGGTCGAGCAGAAGCTCTACGAGCGGGGCA
TCCGCAGCTACCTGCTGGACGGCGACAACGTCCGCTACGGGCTCAACGCCGGCCCGGATCTGCTCGAGGAGCGGCACGGA
CCCGAGTTCGCCCAGCGGTTCGGACTGGGATTCTCCGCCCAGGACCGCGAGGAGAACATCCGCCGGATCGGCGCGGTGGC
GAAGTTGTTCTGCGAGGCCGGCATCATCGCGCTGACGGCCTTCATCAGCCCCTACGTCCGCGACCGGGACGCGATTCGGG
CCACCCTCGACGACGGCGATTTCCAGGAGATCTTCATCGACACCCCGATCGAGATCTGCGAAAAGCGGGATCCCAAAGGG
CTTTACAAGAAGGCGCGGGCCGGTGAGATCAAGGGATTCACCGGGATCGACGACCCCTACGAGGCCCCGCCGCGGCCCGA
ATTGCGGCTCGACGGCGCCGCCAAGGACGCCGAGACGCTGGCCGAGGAGGTGATCGCCCACCTGGAGCGGGTCGGCGTGA
TCGCCACCGACGGTCTTGCGCACACCCGGGGACGCGACGAGGTGACCGCATGA

Upstream 100 bases:

>100_bases
CGAGCCAGGCTCCACCCGGAGCGGGCGCGGCATCCGGTGACGCACAGGTGGTAAGCGGCCGTTGGGGTTTCGCTGCCGTC
CGGGAATACAGGAGTCGGAA

Downstream 100 bases:

>100_bases
ACTACACCGGCCACAACGGCAAGCCGCTGGTGGAGCGGGTGTCCACCGAGAACGCGGCGGCCCGCATCGAGGGCCTGCCG
CGGGTGCCGATCTCGAAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSNNITWHEHKISRGEREQLNGHKGCVIWFTGLSGSGKSTVANVVEQKLYERGIRSYLLDGDNVRYGLNAGPDLLEERHG
PEFAQRFGLGFSAQDREENIRRIGAVAKLFCEAGIIALTAFISPYVRDRDAIRATLDDGDFQEIFIDTPIEICEKRDPKG
LYKKARAGEIKGFTGIDDPYEAPPRPELRLDGAAKDAETLAEEVIAHLERVGVIATDGLAHTRGRDEVTA

Sequences:

>Translated_230_residues
MSNNITWHEHKISRGEREQLNGHKGCVIWFTGLSGSGKSTVANVVEQKLYERGIRSYLLDGDNVRYGLNAGPDLLEERHG
PEFAQRFGLGFSAQDREENIRRIGAVAKLFCEAGIIALTAFISPYVRDRDAIRATLDDGDFQEIFIDTPIEICEKRDPKG
LYKKARAGEIKGFTGIDDPYEAPPRPELRLDGAAKDAETLAEEVIAHLERVGVIATDGLAHTRGRDEVTA
>Mature_229_residues
SNNITWHEHKISRGEREQLNGHKGCVIWFTGLSGSGKSTVANVVEQKLYERGIRSYLLDGDNVRYGLNAGPDLLEERHGP
EFAQRFGLGFSAQDREENIRRIGAVAKLFCEAGIIALTAFISPYVRDRDAIRATLDDGDFQEIFIDTPIEICEKRDPKGL
YKKARAGEIKGFTGIDDPYEAPPRPELRLDGAAKDAETLAEEVIAHLERVGVIATDGLAHTRGRDEVTA

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=223, Percent_Identity=45.2914798206278, Blast_Score=200, Evalue=1e-51,
Organism=Homo sapiens, GI62912492, Length=219, Percent_Identity=44.7488584474886, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI34447231, Length=219, Percent_Identity=44.7488584474886, Blast_Score=188, Evalue=3e-48,
Organism=Escherichia coli, GI1789107, Length=189, Percent_Identity=53.4391534391534, Blast_Score=214, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17542422, Length=219, Percent_Identity=46.1187214611872, Blast_Score=189, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6322852, Length=210, Percent_Identity=48.5714285714286, Blast_Score=194, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24667032, Length=220, Percent_Identity=43.1818181818182, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24667028, Length=220, Percent_Identity=43.1818181818182, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24667036, Length=220, Percent_Identity=43.1818181818182, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24667040, Length=220, Percent_Identity=43.1818181818182, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI116007838, Length=220, Percent_Identity=43.1818181818182, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24667044, Length=220, Percent_Identity=43.1818181818182, Blast_Score=184, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 25508; Mature: 25377

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNITWHEHKISRGEREQLNGHKGCVIWFTGLSGSGKSTVANVVEQKLYERGIRSYLLD
CCCCCCCHHHHHCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GDNVRYGLNAGPDLLEERHGPEFAQRFGLGFSAQDREENIRRIGAVAKLFCEAGIIALTA
CCCEEECCCCCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FISPYVRDRDAIRATLDDGDFQEIFIDTPIEICEKRDPKGLYKKARAGEIKGFTGIDDPY
HHHHHHCCCHHHEEECCCCCCEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC
EAPPRPELRLDGAAKDAETLAEEVIAHLERVGVIATDGLAHTRGRDEVTA
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEECCCHHCCCCCCCCC
>Mature Secondary Structure 
SNNITWHEHKISRGEREQLNGHKGCVIWFTGLSGSGKSTVANVVEQKLYERGIRSYLLD
CCCCCCHHHHHCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GDNVRYGLNAGPDLLEERHGPEFAQRFGLGFSAQDREENIRRIGAVAKLFCEAGIIALTA
CCCEEECCCCCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FISPYVRDRDAIRATLDDGDFQEIFIDTPIEICEKRDPKGLYKKARAGEIKGFTGIDDPY
HHHHHHCCCHHHEEECCCCCCEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCC
EAPPRPELRLDGAAKDAETLAEEVIAHLERVGVIATDGLAHTRGRDEVTA
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEECCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]