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The map label for this gene is crt [H]

Identifier: 41408488

GI number: 41408488

Start: 2686647

End: 2687474

Strand: Reverse

Name: crt [H]

Synonym: MAP2390c

Alternate gene names: 41408488

Gene position: 2687474-2686647 (Counterclockwise)

Preceding gene: 41408490

Following gene: 41408487

Centisome position: 55.64

GC content: 69.81

Gene sequence:

>828_bases
TTGATGAGTGCCGCCGACCATGTGGTCACCGACGAGGCGGTGCTGTACCAGACCACGGAAACCGGCGTTGCGGTCGTGAC
GTTCAACCGGCCCGGGCGGCTCAACGCCTGGGGACCCGACATCTCGAGCGGCTTCTACGCGTGCATCGACCGTGCCGAGG
CGGACCCCGCGGTCCGGGTGATCGTGTTGACGGGCGCCGGTCGGGGCTTCTGCGCGGGCGCCAACCTGGGCGGCGCGGGA
TCCATCGACGCGAAGCTGGGCGACGGCGACACCGACGTCACCGCGTTGGTCGGCGATCGCCATCCCCACTTCCTGACCGC
ACTGCGCAAACCGATCATCGCCGCGATCAACGGCGCCTGCGTCGGCATCGGGCTGACCCACGCCCTGATGTGCGACGTGC
GGTTCGCGGCCGCCGGCGCCAAGTTCGCCACCGCGTTCACCCGCCGGGGACTGGTCGCCGAGTACGGCATCACCTGGATC
CTGCCGCGGCTGGCCGGCTGGGGCGCGGCGATGGACCTGCTGTTGAGCGGGCGCACCTTCTTCGCCGAGGAGGCCGCAAA
ACTCGGGCTGGTCAACGAGATCGTCGCACCCGACGAGCTGATGACCCGCGCCCTGACCTACGCCGACGACATCGCCCGCA
ATTGTTCGCCGGCGTCGCTGGCGGTGATCAAGCGGCAGGCCTACGACGACGCGCTGCGCGACATCGTCGACGTCAGCGCC
CGCGCCGAAACCCTCATGCACGAGTCGCTGCAGCGCCCCGACGTCATCGAGGGCATCACCAGCTTCCTGGAGAAGCGGCC
GCCACGGTTTCCACCCCTGGCCACCTGA

Upstream 100 bases:

>100_bases
CGCCATACCGCAGTTGTGGAATGCGCTACCGATAGGTATACAGTATGGGTACAAACTTGCCTGCTGGGTCAGCCTGCCGG
GTCAGCTGTGAGGGGACGCC

Downstream 100 bases:

>100_bases
CCCGCCGGAAAGGATCATCATGACCGCCCTGAACTATCGCGTGATCGACGTCGACAACCACTATTACGAGCCGCTGGACT
CGTTCACCCGCCACCTCGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MMSAADHVVTDEAVLYQTTETGVAVVTFNRPGRLNAWGPDISSGFYACIDRAEADPAVRVIVLTGAGRGFCAGANLGGAG
SIDAKLGDGDTDVTALVGDRHPHFLTALRKPIIAAINGACVGIGLTHALMCDVRFAAAGAKFATAFTRRGLVAEYGITWI
LPRLAGWGAAMDLLLSGRTFFAEEAAKLGLVNEIVAPDELMTRALTYADDIARNCSPASLAVIKRQAYDDALRDIVDVSA
RAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT

Sequences:

>Translated_275_residues
MMSAADHVVTDEAVLYQTTETGVAVVTFNRPGRLNAWGPDISSGFYACIDRAEADPAVRVIVLTGAGRGFCAGANLGGAG
SIDAKLGDGDTDVTALVGDRHPHFLTALRKPIIAAINGACVGIGLTHALMCDVRFAAAGAKFATAFTRRGLVAEYGITWI
LPRLAGWGAAMDLLLSGRTFFAEEAAKLGLVNEIVAPDELMTRALTYADDIARNCSPASLAVIKRQAYDDALRDIVDVSA
RAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT
>Mature_275_residues
MMSAADHVVTDEAVLYQTTETGVAVVTFNRPGRLNAWGPDISSGFYACIDRAEADPAVRVIVLTGAGRGFCAGANLGGAG
SIDAKLGDGDTDVTALVGDRHPHFLTALRKPIIAAINGACVGIGLTHALMCDVRFAAAGAKFATAFTRRGLVAEYGITWI
LPRLAGWGAAMDLLLSGRTFFAEEAAKLGLVNEIVAPDELMTRALTYADDIARNCSPASLAVIKRQAYDDALRDIVDVSA
RAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=31.4516129032258, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=29.3436293436293, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI70995211, Length=206, Percent_Identity=29.126213592233, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=33.7016574585635, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI221136756, Length=189, Percent_Identity=26.984126984127, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI221136753, Length=189, Percent_Identity=26.984126984127, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260274832, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45643119, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI260275230, Length=213, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4757968, Length=194, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI49355787, Length=194, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI116235487, Length=220, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI25453481, Length=173, Percent_Identity=24.8554913294798, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI51538573, Length=173, Percent_Identity=24.8554913294798, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=35.8778625954198, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=32.1969696969697, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=31.0606060606061, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788597, Length=264, Percent_Identity=26.8939393939394, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082183, Length=274, Percent_Identity=27.3722627737226, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=256, Percent_Identity=30.078125, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=207, Percent_Identity=29.951690821256, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=255, Percent_Identity=26.2745098039216, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=181, Percent_Identity=31.4917127071823, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=262, Percent_Identity=27.0992366412214, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=263, Percent_Identity=28.1368821292776, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=32.295719844358, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=32.295719844358, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=31.0077519379845, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654903, Length=248, Percent_Identity=26.2096774193548, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650670, Length=249, Percent_Identity=29.3172690763052, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357171, Length=197, Percent_Identity=31.9796954314721, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922422, Length=255, Percent_Identity=24.3137254901961, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921000, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583077, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583079, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29157; Mature: 29157

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSAADHVVTDEAVLYQTTETGVAVVTFNRPGRLNAWGPDISSGFYACIDRAEADPAVRV
CCCCCCCEECCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEE
IVLTGAGRGFCAGANLGGAGSIDAKLGDGDTDVTALVGDRHPHFLTALRKPIIAAINGAC
EEEECCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCH
VGIGLTHALMCDVRFAAAGAKFATAFTRRGLVAEYGITWILPRLAGWGAAMDLLLSGRTF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCHH
FAEEAAKLGLVNEIVAPDELMTRALTYADDIARNCSPASLAVIKRQAYDDALRDIVDVSA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMSAADHVVTDEAVLYQTTETGVAVVTFNRPGRLNAWGPDISSGFYACIDRAEADPAVRV
CCCCCCCEECCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEE
IVLTGAGRGFCAGANLGGAGSIDAKLGDGDTDVTALVGDRHPHFLTALRKPIIAAINGAC
EEEECCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCH
VGIGLTHALMCDVRFAAAGAKFATAFTRRGLVAEYGITWILPRLAGWGAAMDLLLSGRTF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCHH
FAEEAAKLGLVNEIVAPDELMTRALTYADDIARNCSPASLAVIKRQAYDDALRDIVDVSA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]